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5 Cards in this Set
- Front
- Back
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Genetic Linkage |
Unlike Mendel's experiments, genes can be linked to each other or reside on the same chromosome. If 2 genes are close together on the same chromosome pair, they do not assort independently. |
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Genetic Distance |
The distance between gene loci on a chromosome can be measured in terms of the recombination frequency (RF), produced by crossing over between two loci during meiosis. Roughly 1% recombination = 1 map unit (m.u.) for short distances. |
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Gene Order/ 3-factor cross (trihybrid cross) |
Interlocks map distances based on recombination measurements are roughly additive and can be used to determine gene order. |
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Interference |
One crossover can influence the occurrence of a second crossover in an adjacent region. Interference distorts map distance. |
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Mapping Function |
For RFs larger than 15%, the 1 to 1 relationship between RF and m.u. breaks down. (ex. an RF of 27.5% actually equals 40 m.u.) |
