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16 Cards in this Set
- Front
- Back
What is Corynebacterium diphtheriae called?
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Diphtheria: gram positive anerobe
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What effects does Coryn. Diphteriae have on the human body?
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-colonization and growth forms lesions on the upper respiratory tract.
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How can the lesions formed by Coryn. Diphtheriae affect kids.
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By blocking their airway and causing death
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What kind and effect does the toxin have on the body?
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-A-B toxin where the "A" goes into the host(halt protein synthesis) and "B" is the binding part.
-Systemic effect on the body. |
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What strains make the toxins?
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Only the strains that can find a matching binding site.
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How does the toxin of Diphtheriae work?
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It destroys the epithelium and starts inflammatory response. Then the necrotic tissue and the fibrin and blood cells form a grayish membrane.
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What is result of distant toxin activity of Diphtheriae?
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Myocarditis
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What is the treatment of Diphtheriae bacteria and toxin?
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-Diphtheriae anti-toxin for the toxin
-Erythromycin to eliminate bacteria |
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What are three characteristics of Listeria Monocytogenes?
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-Gram positive
-non-spore forming -grows at refer temps |
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Why is Listera Mono. a big problem for pregnant women?
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Because it moves cell to cell thus can infect the fetus.
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Why are antibiotics not an effective treatment of Listeria Mono.?
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Because it is a intracelluar pathogen and moves from cell to cell.
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What are the major sources of Listeria Mono?
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In foods you don't cook
-soft cheeses -Spam |
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Effects of Listeria Mono. in humans.
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Baby:no defense to fight bacteria
Healthy people: Mild GI,Meningitis Immunocomprinmised:most patients, more severe GI |
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What makes Listeria Mono. more evasive bacteria?
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It has an immune response to Macrophages; can get out of phagolysosome
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Where is Listeria Mono. located throughout the body?
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-Doesn't stay in the GI tract
-involves the liver and the spleen sometimes ending up in the CNS |
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What is the best treatment for Listeria mono.?
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-Control and prevention
-Elimination from the environment |