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22 Cards in this Set

  • Front
  • Back

Pth effects

Bone resorption


Kidney


Increase Ca2+ absorption


1,25 DHCC synthesis (1 a hydroxylase enzyme)

Vit D

Increase Ca2+ absorption I'm gut


Synergises with pth on Bone


Inhibits 1 a hydroxylase

Endocrine causes of osteoporosis

Hypogonadism (Dec oestrogen)


Excess glucocorticoids


Hyperthyroidism


Hyperparathyroidism


Type 1 diabetus

Epidemiology osteoporosis related fracture women

50%

Mean age menopause

53

Only source of female sex hormones after menopause

Adrenal androgens. Peripheral conversion to oestrogen

Placental steroids

Hpl


Oestrogen


Progesterone


Cortisol


Placental Crh


Trophoblastic steroid

Bhcg

Pyknosis def

Chromatin condensation / shrinkage

Karyorrhexis def

Fragmentation of the nucleus

Karyolysis def

Dissolution of chromatin by dnase causing a fading in the basophilia of the cell

Opacificafion of cytoplasm fed

Denaturation of proteins with aggregation

Adenoma def

Benign tumour of glandular epithelial origin

Causes monocytosis

Hair disk a pa

Causes eosinophilia

Hand

Right shifted neutrophils

Left shifted neutrophils

Causes lymphocytosis

Causes lymphopenia

Criteria Child under overweight obese

Less than 2nd


Above 91st


Above 98th

Causes of incontinence

G

Croup

Acute viral laryngo-tracheobronchitis


Seal noise


Hib and parainfluenza