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42 Cards in this Set

  • Front
  • Back
What are the functions of water?
- Cellular metabolism (without water, our cells can't function)
- Transportation of nutrients
- Digestion of food
- Temperature regulation (temp. increases when not enough water)
- Maintenance of ECF
- Acid-base balance
- Waste excretion
The body has 50- 80% of water. List the factors that makes this percentage vary.
- Age (younger the individual, greater the water composition)
- Body weight (the more muscle, the more water)
- Sex (men have more water than women)
What is the difference between sensible and insensible water loss?
- Insensible water loss is hard to measure (ex: sweating, water loss from lungs, ryv.z)
- Sensible water is measurable
How do you determine a person's output per hour?
- 1 ml per kilogram of body weight per hour
- Normal output is 40-80 ml per hour
- Less than 30 ml could indicate renal failure
How much body fluid is in the intracellular fluid (ICF)?
75%
How much body fluid is in the extracellular fluid (ECF)?
25%
What are the two components of extracellular fluid?
- Intravascular (circulatory system) : 5%
- Interstitial (third space): 20%
What is edema?
- Increase fluid in interstitial space
What is the #1 way of maintaining and regulating fluid balance?
Thirst
How is thirst regulated?
- The hypothalamus regulates thirst which has osmoreceptors
- Osmoreceptors sense osmotic pressure of body fluids
- As osmotic pressure (concentration) increase, we become thirsty/thirst reflex is stimulated
- As we have decrease concentration osmoreceptors sense, there is a decrease thirst
Define osmosis.
The movement of water between areas and cells of the body.
Describe the action of antidiuretics (ADH).
- ADH causes kidneys to reabsorb water; thus decreasing urine output.
- The body notices fluid volume deficit
- This stimulates the posterior pituitary to send out ADH
- Releases anti "urine" hormone
- Kidneys reabsorb water
- Increases circulating volume of water, increases blood volume, and decreases osmolarity
Describe the action of Aldosterone.
- Aldosterone holds sodium, therefore water.
- Juxtoglomuler (JG) in kidney repond to decrease blood pressure or volume
- JG cells stimulate the renin angiotension feedback loop
- Causes kidney to hold sodium.
- Remember water and Na stick together.
- Thus, water is retained.
- K+ is given away during process.
How many kg equals a liter of water? How many ml equals a pound (lb)?
- 1 kg = 1 liter
- 1 lb = 500 ml
What is hypovolemia?
- Decrease fluid volume
- Fluid volume deficit
- Dehydration
What are the risk factors for fluid volume deficit (FVD)?
- Age (infants and elderly kidneys less able to compensate; unable to quickly and aggressively released ADH and aldosterone)
- Increased loss of fluid
- Decreased intake (nausea, anorexia, confusion)
What are some things that lead to FVD?
- Nasogastric drainage
- Vomiting, diarrhea, drainage
- Diuresis, diaphoresis
- Fluid losses through the skin from surgery, trauma, burns
Dehydration symptoms arise when fluid loss is more than what percentage of body weight?
Dehydration symptoms arise when fluid los is more than 2% of body weight
What is hypervolemia?
- Overhydration
- Fluid volume excess
- Acute weight gain of 5% of body weight
What are the risk factors for fluid volume excess (FVE)?
- Decreased urinary output (renal failure and decreased cardiac output)
- Increased intake (IV therapy)
What do you see in babies with fluid volume deficit (FVD)?
- Sunken fontanels
- No tears
- Very dry mouth and tongue
- Decrease skin turgoe
- Sunken abdomen
What are the FVE symptoms?
- Neck vein distention
- Congestive heart failure
- Pulmonary edema
- Full bounding pulses
- Elevated blood pressure
- Peripheral edema
- Weight gain
- First sign is at the scene (the lungs); thus, listen to the lungs to see if there's fluid in the lungs (crackles and rales)
What are the three types of Saline Intravenous Solution. What are their purpose?
- 0.45% Sodium Chloride given to a person with hypernatremia
- 0.9% Sodium Chloride given to some if dehydrated; equal to our normal healthy body concentration of sodium chloride in the fluid
- 3% Sodium Chloride - given to person with hyponatremia
What is the normal range of serum K+ levels?
3.5-5 mEq/l
What are the functions of Potassium?
- Transmission of nerve impulses: cardiac and skeletal muscles
- Acid/Base Balance: control H ion concentration
- Carrier for glucose and insulin
What is the range for hyperkalemia?
- More than 5 mEq
What can lead to hyperkalemia?
- Excess intake (IV replacement therapy, multiple blood transfusion, potassium supplement without need to replace)
- Decreased loss (potassium-sparing diuretics, renal failure: decrease output)
- Shifting of K+ out of cell
What are the signs and symptoms of hyperkalemia?
- Gastronintestinal (nausea, vomiting, diarrhea, hyperactive bowel sounds)
- CNS (numbness, paraesthesia: tingling sensations)
- Muscles (irritability, hyperactive reflexes)
- Cardiovascular (peak T waves, ventricular fibrillation, CARDIAC ARREST)
- Kidneys (oliguria: decrease urine output)
Can we IV push K+?
- Never IV push K+
- K+ is adminstered on a pump or witin a bag
What are the treatments for hyperkalemia?
- Give Lasix to those with a functional kidney; avoid additional IV and oral intake
- For those with decreased kidney function, give insulin and dextrose infusion as it causes K+ to go into the cell
- Dialysis
What is considered hypokalemia?
- Less than 3.5 mEq/l
- Kidney is not good at conserving K+ frequently occuring, develops quickly
What can cause hypokalemia?
- Dcreased intake (failure to replace losses, decreased food and fluid intake)
- Increased loss (GI losses, the biggest loss: vomiting and diarrhea, potassium losing diuretics, long term steroid therapy)
- Shift of K+ into cells
- Excess aldosterone secretion
What are the signs and symptoms of hypokalemia?
- Gastrointestinal (anorexia, nausea, paralytic ileus: no bowel sounds)
- CNS: lethargy, confusion, diminished deep tendon relexes
- Muscles: weakness, paralysis
- Cardiovascular: dyshythmias, EKG changes, flattened T waves, "U" waves
- Kidneys: renal damage, < capacity to concentrate urine
What is the treatment for hypokalemia?
- Stop loss
- Monitor patient: blood level and signs and symptoms
- Replacement with foods (dried fruit), oral meds (take with good due to GI irritant), IV therapy (irritating to the vein) , never IV push
What is the normal range for sodium levels?
-135-145 mEq/L
What may be the causes of hypernatremia?
- Decrease water intake (comatose, NPO)
- Increased water output (watery diarrhea, diaphoresis, fever with inrcreased respiration, diabeters insipidus)
- Increased NA intake: IV solution (0.9% NaCl), near drowning in sea water, increase aldosterone secretion
What are the signs and symptoms of hypernatremia?
- Think DRY
- Intense thirst
- Red dry tongue
- Flush skin
- Nonelastic skin turgor
- Dry, sticky mouth membranes
- Restlessness, agitation
- Anuria, oliguria (retain water)
What is the treatment for hypernatremia?
- Monitor patient: blood level and signs and symptoms
- Replace water until NA level returns to normal: Oral intake, IV replacement (5% D/W); don't give IV with sodium chloride, just solution that dilutes the fluid
- Protect patient if confused
What is the sodium level if a person has hyponatremia?
- < 135 mEq
- Think LOTS OF WATER
- Loss of Na+ without loss of water
- Excess water, low Na+
What can be the causes for hyponatremia?
- Increased water intake: Na+ free IV fluids (hypotonic solution), tap water eneam
- Decreased water output: renal disease, excess water
- Increased Na+ loss: vomiting, irrigating NG tube with water
- Decreased Na+ intake: low Na+ diet, Na+ free liquids with diaphoresis (loss of more Na+ in proportion to water)
What are the signs and symptoms of hyponatremia?
- Absence of thirst
- Abdominal cramping
- Clammy skin
- Finger printing on the sternum
- Disorientation
- Headaches
- Fatigue
What is the treatment to hyponatremia?
- Stop the cause
- Monitor patient: Blood level and signs and symptoms
- Decrease water intake
- Fluid replacement with NA+ (Oral and IV); would give hypertonic 3% sodium chloride solution IV
- Irrigate NG tube with Nacl, NOT WATER.