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261 Cards in this Set

  • Front
  • Back
Don poured himself half a glass of milk. Because he was thirsty, he added half a glass of water to it. In doing so, Don

A) doubled the milk's nutritive density.
B) increased the milk's nutritive density by 50%.
C) halved the milk's nutritive density.
D) reduced the milk's nutritive density by 100%.
E) reduced the milk's nutritive density by 33.33%.
C) halved the milk's nutritive denstity
People tend to feel hungry

A) at their regular mealtimes, whenever they are.
B) at noon.
C) in the evening.
D) in the morning.
E) B, C, and D
A) at their regular mealtimes, whenever they are.
All set-point models have

A) a set-point mechanism.
B) a detector mechanism.
C) an effector mechanism.
D) all of the above
E) a thermostat.
D) all of the above
Glucostatic theory is to lipostatic theory as

A) glucose is to fat.
B) short-term is to long-term regulation.
C) long-term is to short-term regulation.
D) both A and B
E) both A and C
D) Both A and B
5. As a meal is consumed,

A) there is a rapid decline in the positive-incentive values of the particular tastes that are being consumed.
B) there is a decline in the positive-incentive value of the foods that are being consumed but only once they have been completely digested.
C) there is a gradual decline in the positive-incentive value of all foods.
D) both A and C
E) both B and C
D) Both A and C
6. Leptin is to insulin as subcutaneous fat is to

A) limb fat.
B) arcuate fat.
C) visceral fat.
D) hind fat.
E) melanocortins.
C) visceral fat
7. Animals learn to

prefer the tastes of key vitamins and minerals in their food.

prefer tastes that have been followed by an infusion of calories.

avoid tastes that have been followed by gastrointestinal illness.

all of the above

both B and C
Both B and C
8. The case of R.H., the man who forgot not to eat, suggests that

all obese people eat too much.

the motivation to eat a meal does not normally come from the decline of energy resources.

only amnesic patients have no set points.

amnesic patients forget their set points.

there are set points for complex foods such as veal parmigiana.
the motivation to eat a meal does not normally come from the decline of energy resources.
Ob/ob mice

convert calories to fat more efficiently than do control mice.

use their calories more efficiently than do control mice.

have high leptin levels.

all of the above

both A and B
Both A and B
Most of the body's energy reserves are stored in the form of

glycogen.

fat.

glucose.

protein.

alcohol.
fat
__________ have been shown to reduce hunger, eating, and body weight.

Glutamate agonists

Serotonin agonists

Acetylcholine antagonists

Dopamine antagonists

Norepinephrine antagonists
Serotonin agonists
Rats have been shown to prefer flavors that

they experience in their mother's milk.

they smell on the breath of other rats.

taste of vitamins.

both A and B

both A and C
Both A and B
Evidence from the sham-eating study of Weingarten and Kulikovsky (1989) suggests that the amount that we eat at a meal is influenced by

our previous experience of the physiological consequences of the same food.

the presence of anticipatory eating responses.

the amount of sodium in it.

the length of the meal.

the rate at which the meal is digested.
our previous experience of the physiological consequences of the same food.
(Picture of a mouse) Illustrated here is a __________ preparation.
sham-eating
People with __________ act as if they are starving.

LH lesions
dopamine agonists
Prader-Willi syndrome
amnesia
Down syndrome
Prader-Willi syndrome
Settling-point models of weight regulation can explain why

body weight remains relatively constant in many adults.

many adults display enduring changes in body weight.

metabolic changes reduce the impact of starvation or gluttony.

dieters regain lost weight after they go off their diets.
many adults display enduring changes in body weight.
Most humans have a fondness for __________ tastes.

sweet
fatty
salty
all of the above
both B and C
all of the above
Rats eat __________ when fed __________.

less; in groups
less; a cafeteria diet
more; in groups
more; in isolation
more; following VMH stimulation
more; following VMH stimulation
The VMH hyperphagia syndrome comprises two phases. In chronological sequence, these phases are the

aphagia phase and the adipsia phase.
adipsia phase and the aphagia phase.
dynamic phase and the static phase.
hyperphagia phase and the hypophagia phase.
static phase and the dynamic phase.
dynamic phase and the static phase.
21. According to the positive-incentive theory, the main cause of hunger in food-replete conditions is

a shortage of calories in the body.
the presence of food or the anticipation of its availability.
deviation from an energy set point.
deviation from a positive-incentive set point.
high levels of insulin.
the presence of food or the anticipation of its availability.
22. All set-point systems are __________ systems.

negative feedback
positive feedback
no-feedback
settling point
positive-incentive
negative feedback
Evidence suggests that the effects of large bilateral VMH lesions on eating are, in part, caused by damage to the __________ or its connections.

paraventricular nuclei
lateral geniculate nuclei
lateral hypothalamus
preoptic nuclei
amygdala
paraventricular nuclei
Which of the following cases can be readily accounted for by the leaky-barrel model, but not by traditional set-point models?

A women married a cook, and her weight rapidly increased by 5 kilograms; the added weight stayed, despite her efforts to lose it.
A business executive became a marathon runner, and her food consumption went up while her weight went down and stayed down.
A dieter changed his life style, he lost 30 kilograms, he never put the weight back on, and he never felt any compulsion to overeat.
all of the above
none of the above
all of the above
The leaky-barrel model of body weight regulation is a

settling-point model.
negative-feedback model.
an improved alternative to the thermostat analogy.
all of the above
none of the above
all of the above
Injections of insulin

usually increase blood glucose.
usually trigger eating.
trigger eating only if the doses are large enough to produce reductions in blood glucose that are greater than those that would normally occur under typical free-feeding conditions.
both A and B
both A and C
trigger eating only if the doses are large enough to produce reductions in blood glucose that are greater than those that would normally occur under typical free-feeding conditions.
31. Eating sweet and fatty foods is adaptive for many mammals living in the wild because in nature these tastes

are characteristic of energy-rich foods.
are often found in association with beneficial vitamins and minerals.
are only rarely associated with high-calorie foods.
all of the above
both A and B
both A and B
The conversion of protein to glucose is called

gluconeogenesis.
glucagon.
glucogenesis.
the cephalic phase.
glucosis.
gluconeogenesis.
According to Woods, the hunger that one experiences as a regular mealtime approaches is

your body crying out for energy.
caused by an energy deficit.
the result of the changes occurring in your body in preparation for the homeostasis-disturbing meal.
the result of elevated blood glucose levels.
the result of low levels of insulin.
the result of the changes occurring in your body in preparation for the homeostasis-disturbing meal.
35. Human subjects who have had their stomachs surgically removed eat

so little that they need to be fed intravenously to survive.
much more than do humans with stomachs.
continue to maintain their body weights by eating more meals of smaller size.
only through implanted fistulas.
only wet food.
continue to maintain their body weights by eating more meals of smaller size.
In one experiment (Weindruch et al., 1986), the caloric intake of mice was reduced by up to 25, 55, or 65%. The benefits of the caloric restriction were greatest in the 65% group These benefits included

an increased life span.
a reduced incidence of cancer.
improved immune responses.
all of the above
none of the above
all of the above
Cultural practices that promote obesity include the practice of

eating three large meals per day whether one is hungry or not.
serving food at all social gatherings.
adding sweet, salty, and fatty tastes to foods to increase their positive-incentive value.
serving food in different courses of progressively increasing palatability.
all of the above
all of the above
__________ encourages the consumption of a varied diet.

Body fat
Sensory-specific satiety
A set point
Palatability
Negative feedback
Sensory-specific satiety
According to Woods, in the short-term, meals are

controlled by set points.
homeostasis-disturbing.
homeostasis-promoting.
likely to be eaten during the cephalic phase.
likely to be initiated during the fasting phase.
homestasis-disturbing
Efforts to develop a leptin treatment for typical cases of human obesity have been

disappointing.

promising.

very successful.

successful, but in only 50% of obese people.

waiting for support from granting agencies and ethics boards before they can begin.
disappointing
46. CCK, bombesin, glucagon, and somatostatin

are peptides.

are released from the gut.

have been reported to increase food intake.

all of the above

both A and B
both A and B
47. Insulin promotes the

conversion of glucose to glycogen and fat.

use of glucose as the primary source of energy by the body.

storage of glycogen and fat.

all of the above

none of the above
all of the above
48. A major problem with the set-point theory of body weight regulation is that it

cannot explain the effects of satiety peptides.

cannot explain how LH lesions increase hunger.

cannot explain the increasing prevalence of obesity.

is too parsimonious.

is too vague.
cannot explain the increasing prevalence of obesity.
49. According to the text, obesity is now prevalent in industrialized countries because

high-positive-incentive value foods are continuously and readily available in these countries.

humans have evolved to eat as much as they can when food is available.

cultures have evolved to promote eating when food is available.

all of the above

both A and B
all of the above
50. Animals with a sodium deficiency

quickly learn to prefer the taste of sodium salt.

slowly learn to prefer the taste of sodium salt by experiencing its health-promoting effects.

slowly learn to prefer the taste of sodium salt by experiencing the alleviation their symptoms.

automatically prefer the taste of sodium salt.

both B and C
automatically prefer the taste of sodium salt.
51. Sham-eating procedures typically reduce caloric intake into the bloodstream during a meal by

100%.

40%.

60%.

80%.

20%.
100%
52. Many hunger and satiety peptides have receptors in the

hippocampus.

hypothalamus.

amygdala.

prefrontal cortex

striatum.
hypothalamus
53. Animals with a sodium deficiency, tend to favor diets rich in sodium because

they learn to recognize the health-promoting effects of sodium-rich diets.

they learn to recognize the health-disrupting effects of sodium-free diets.

the deficiency produces an immediate preference for the taste of sodium salts.

sodium is usually found in thiamine-rich diets.

thiamine is usually found in sodium-rich diets.
the deficiency produces an immediate preference for the taste of sodium salts.
There are __________ phases of energy metabolism.

2

14

3

5

15
3
Interest in the efficiency of polyphasic sleep was stimulated by stories of

Leonardo da Vinci.
Michelangelo.
Titian.
Hebb.
Picasso.
Leonardo da Vinci
Following the completion of one week of REM-sleep deprivation, volunteers

normally sleep for about 16 hours and then awaken refreshed.

gradually increase the amount of REM sleep that they have each night until they get back to their original baseline.

have a greater than usual proportion of REM sleep for 2 or 3 nights.

often display psychosis for 2 or 3 days and report particularly lurid dreams.

both C and D
have a greater than usual proportion of REM sleep for 2 or 3 nights.
The first circadian gene to be discovered in mammals was

clock.
alarm.
circa.
tau.
invert.
tau
Evidence suggests that melatonin functions as a

stimulant.
chronobiotic.
catecholamine.
neurotransmitter.
both C and D
chronobiotic
The first EEG stage of a night's sleep is

alpha.
Stage 1.
stage 3.
stage 4.
stage 2.
stage 1
Narcolepsy is most often considered to be a disorder of

insomnia.
hypersomnia.
myoclonus.
restless legs.
sleep apnea.
hypersomnia
Loss of 3 or 4 hours of sleep for one night has been found to reliably

disrupt the performance of intelligence tests.
disturb mood.
disrupt motor performance.
reduce strength.
all of the above
disturbs mood
Most mammals and birds

sleep.
have sleep that is similar to human sleep.
have sleep that is characterized by high-amplitude, low-frequency EEG activity that is punctuated by periods of low-amplitude, high frequency EEG activity.
all of the above
none of the above
all of the above
There are three classes of drugs that influence sleep: hypnotics, antihypnotics, and a third class that

is derived from benzodiazepines.
includes melatonin.
comprises drugs that influence the circadian rhythmicity of sleep without increasing or decreasing it.
all of the above
both B and C
both B and C
The case of Miss M. is interesting because

brain damage had left her unable to sleep.
by using stimulant drugs she was able to reduce her sleep to 1 or 2 hours per night.
her lack of sleep had made her paranoid.
she had been able to train herself with great effort not to sleep when she had better things to do with her time.
none of the above
none of the above
K complexes and sleep spindles

occur during stage 2 sleep.
are EOG waves.
are EEG waves.
both A and B
both A and C
both A and C
When they fall asleep, narcoleptics immediately

wake up.
snore.
go into REM sleep.
display cataplexy.
go into stage 4 sleep.
go into REM sleep
Cells of the suprachiasmatic nuclei display circadian cycles of

gene expression.
osmosis.
sleep.
degeneration.
regeneration.
gene expression
Which of the following dangerous effects usually occur in humans after periods of sleep deprivation longer than 24 hours?

schizophrenic tendencies
lasting reductions in cortical activity
chronic hormone imbalances
chronic cardiac irregularities
none of the above
none of the above
Adaptation theories of sleep assume that we are programmed to sleep at night


only if we expend energy during the day.
only if we expend more energy than we consume during the day.
only if we do not sleep during the day.
regardless of what we do during the day.
only if we eat three times per day.
regardless of what we do during the day
Under normal living conditions, most people sleep during

body temperature homeostasis.
internal desynchronization.
free-running temperature cycles.
the falling phase of the circadian body-temperature cycle.
the rising phase of the circadian body-temperature cycle.
the falling phase of the circadian body temperature cycle
After several nights of REM-sleep deprivation, penile erections often

do not occur during sleep.
become difficult to achieve during wakefulness.
begin to occur during SWS.
make it difficult to get back to sleep.
become embarrassing.
begin to occur during SWS.
Strong evidence that REM-sleep is not essential for memory comes from the study of patients

with brain damage.
after electroconvulsive shock.
who can't sleep.
who get little or no REM sleep because they regularly take antidepressant drugs.
who get little or no sleep because they are narcotic addicts.
who get little or no REM sleep because they regularly take antidepressant drugs.
According to Hobson's activation-synthesis theory of dreaming, dream content reflects

repressed feelings of inferiority.
random brain stem activity and the cortex's inherent tendency to try to make sense of these ambiguous signals.
an interplay between the thalamus and hypothalamus.
lucid impulses acting on repressed discharges.
REM activity in conflict with alpha.
random brain stem activity and the cortex's inherent tendency to try to make sense of these ambiguous signals.
Microsleeps are usually about __________ long.
3 seconds
25 seconds
1 minute
5 minutes
7 minutes
3 seconds
Many sleep-deprivation studies have assessed its impact on human

physiological function.
mood.
cognition.
all of the above
none of the above
all of the above
. Which of the following can entrain the circadian sleep-wake cycles of animals living under constant lighting conditions?

regular daily bouts of social interaction
regular daily meals
regular daily bouts of exercise
all of the above
none of the above
all of the above
After an entire week of REM-sleep deprivation, about how many times in one night did volunteers have to be awakened to prevent them from experiencing bouts of REM sleep?

0
5
17
25
67
67
Slow-wave sleep seems to play a particularly important role in the recuperative effects of sleep. The following is major evidence for this conclusion:

People regain only a small portion of their lost sleep following a period of sleep deprivation, but they regain most of their lost stage 4.
Most long sleepers get a higher proportion of stage 3 and 4 sleep than short sleepers.
Volunteers who have reduced the amount that they sleep each night have usually
accomplished this without substantially reducing the amount of stages 3 and 4 sleep.
all of the above
both A and C
both A and C
Which of the following statements is not correct?

Drugs that increase the activity of catecholamine neurotransmitters are hypnotics.
Cocaine, amphetamine, and tricyclic antidepressants are antihypnotic drugs.
Stimulants suppress REM sleep more than they do the other phases of sleep.
Stimulant drugs are antihypnotics.
Norepinephrine and dopamine are catecholamines.
Drugs that increase the activity of catecholamine neurotransmitters are hypnotics.
Paradoxically, people suffering from sleep apnea are often diagnosed as suffering from either insomnia or

restless legs.
nocturnal myoclonus.
hypersomnia.
all of the above
either A or B
hypersomnia
One of the most important features of sleep is that its efficiency increases in response to

sleep reduction.
cognitive overload.
light.
tricyclic antidepressants.
stress.
sleep reduction
. In view of the evidence, the widespread practice of taking melatonin to promote sleep is

dangerous and should be stopped.
definitely a waste of time.
likely to be of no more than minor benefit.
likely to have some major sleep benefits.
likely to improve all stages of sleep except REM.
likely to be of no more than minor benefit.
. In the initial report of the relation between dream recall and REM sleep, what proportion of awakenings from REM sleep led to dream reports?

100%
80%
60%
40%
20%
80%
The carousel apparatus has been used to study sleep deprivation in

rats.
men and women.
children.
horses.
monkeys.
rats
The various phenomena of REM sleep appear to be controlled by circuits scattered throughout the

basal forebrain.
posterior hypothalamus.
caudal reticular formation.
midbrain.
colliculi.
caudal reticular formation
Many cases of insomnia appear to be

recuperative.
iatrogenic.
circadian.
associated with cataplexy.
psychotic.
iatrogenic
A large group of patients who sought treatment for insomnia were found in one study to sleep __________ hours per night.
6.5
. During microsleeps, people

often fall down.
become less responsive to external stimuli.
display a sleep EEG.
all of the above
both B and C
both B and C
Companies that employ shift workers have improved productivity and job satisfaction by

scheduling only phase advances.
scheduling only phase delays.
accelerating the zeitgebers.
desynchronizing the zeitgebers.
desynchronizing body temperature.
scheduling only phase delays.
There is good evidence that the internal circadian clock is located in the

suprachiasmatic nuclei.
raphé nuclei.
caudal reticular formation.
basal forebrain.
optic nerves.
suprachiasmatic nuclei
. A large, well conducted comparison between long sleepers and short sleepers, Fichten and colleagues found that the short sleepers

slept less.
suffered from more mental illness.
had poorer memories.
had shorter life expectancies.
accomplished less.
slept less
. A vivid dreamlike state during wakefulness, often just as one awakens or falls asleep, is

a hypnagogic hallucination.
cataplexy.
sleep paralysis.
narcolepsy.
sleep apnea.
a hypnagogic hallucination
The finding that sleep becomes more efficient in people who regularly sleep less is a key finding because it indicates that

sleep-deprivation studies can indicate how much sleep people need only if the volunteers who are being studied are efficient sleepers.
sleep is a positive incentive.
sleep can be made more efficient by reinforcements and punishments.
only circadian theories can account for the negative effects of sleep deprivation.
sleep can be conditioned.
sleep-deprivation studies can indicate how much sleep people need only if the volunteers who are being studied are efficient sleepers.
REM sleep without the usual core muscle atonia is likely a consequence of damage to the

caudal hypothalamus.
cerveau isolé.
nucleus magnocellularis.
supraoptic nucleus.
subfornical organ.
nucleus magnocellularis.
Sleep spindles and K complexes are characteristic of

SWS.
stage 2 sleep.
REM sleep.
delta sleep.
stage 3 sleep.
stage 2 sleep.
The stage of sleep EEG that follows the second bout of stage 2 sleep during a normal night's sleep is

emergent stage 3.
initial stage 1.
emergent stage 1.
emergent stage 2.
stage 3.
emergent stage 1
Electrical stimulation of the __________ awakens sleeping cats.

anterior hypothalamus
cerebellum
diencephalon
reticular formation
basal forebrain
reticular formation
Because REM sleep is similar to wakefulness in several respects, it makes sense that REM sleep circuits are controlled by a structure involved in maintaining wakefulness: the

thalamus.

basal forebrain.

reticular activating system.

cerveau isolé.

both A and B
reticular activating system.
48. The effects of the carousel apparatus are difficult to interpret because

it can deprive rats of only a small amount of sleep.

the volunteers have to sleep in wet pajamas.

in addition to producing sleep deprivation, it produces confounding stress.

it prevents microsleeps.
in addition to producing sleep deprivation, it produces confounding stress.
It is impossible for a human to stay awake longer than __________ hours without experiencing life-threatening physiological problems.


24
36
48
60
none of the above
none of the above
Slow-wave sleep seems to play a particularly important

recuperative role.
psychological role.
circadian role.
physiological role.
mnemonic role.
recuperative role.
Volunteers regain little of their lost sleep after a period of sleep deprivation, but they regain most of their lost
Question 100 options:

stage 4 sleep.

dream time.

REM sleep.

initial stage 1 sleep.

both B and C
stage 4 sleep
Clock is a circadian gene; it was discovered in

mice.

sunflowers.

dogs.

humans.

monkeys.
mice
. Cataplexy is common in cases of

narcolepsy.

insomnia.

anxiety.

pseudoinsomnia.

nocturnal myoclonus.
narcolepsy
The most influential circadian zeitgeber is the

hippocampus.

light-dark cycle.

amygdala.

free-running period.

hyrax.
light-dark cycle.
. Disorders of excessive sleep or sleepiness are classified as

insomnia.

hypersomnia.

iatrogenic.

hyposomnia.

REM-sleep disorders.
hypersomnia.
The following is a prediction of many recuperation theories of sleep:

Long periods of wakefulness will produce physiological and behavioral disturbances.

The disturbances produced by sleep deprivation will grow worse as the deprivation continues.

After a period of sleep deprivation, most missed sleep will be regained.

all of the above

both A and C
all of the above
Cocaine hydrochloride

is a dopamine agonist.
reduces the reuptake of dopamine from synapses by blocking dopamine transporters.
is a dopamine antagonist.
both A and B
both B and C
Both A and B
__________ tolerance to psychoactive drugs is tolerance that occurs because less drug gets to its site of action in the brain.

Contingent
Metabolic
Situationally specific
Functional
In vitro
Metabolic
Although __________ is extremely addictive, there are few serious withdrawal symptoms when a characteristic binge is terminated.

cocaine
alcohol
nicotine
morphine
opium
cocaine
5. Which of the following drugs is a local anesthetic?

alcohol
morphine
cocaine
nicotine
ethyl alcohol
cocaine
. Pregnant females who use __________ risk bearing a child with physical deformities and mental retardation.

alcohol
nicotine
morphine
caffeine
marijuana
alcohol
Cocaine sprees are the product of the interaction between the high positive-incentive value of cocaine and

tolerance.
alcohol.
schizophrenia.
paranoia.
convulsions.
tolerance
Which of the following drugs has effects like those of amphetamine?

marijuana
cocaine
LSD
morphine
valium
cocaine
Which of the following drugs is a commonly prescribed analgesic?

morphine
caffeine
cocaine
alcohol
heroin
morphine
. Although __________ is classified as a depressant, it has stimulant effects at low doses.

alcohol
tobacco
cocaine
amphetamine
morphine
alcohol
Many addicts who are motivated to "kick their habit" manage to stop taking their drug, but they often
relapse.
become tolerant.
recover.
regret it.
become ill for months.
relapse
Which of the following drugs produces Buerger's disease?

tobacco
morphine
marijuana
cocaine
alcohol
tobacco
Withdrawal from which of the following drugs produces convulsions?

morphine
heroin
alcohol
cocaine
both A and B
alcohol
. Which of the following illicit drugs was grown by George Washington as a commercial crop?

alcohol
opium
tobacco
marijuana
magic mushrooms
marijuana
Which form of amphetamine is more potent than d-amphetamine?

ecstasy
ice
methamphetamine
MDMA
all of the above
all of the above
. Which of the following routes of drug administration offers the least opportunity to counteract the effects of an overdose?

IV
IM
SC
through mucus membranes
oral
IV
Some drugs can be effectively administered through mucous membranes. One such drug is

cocaine.
heroin.
morphine.
nicotine.
caffeine.
cocaine
The substantia nigra is

in the mesencephalon.
part of the striatum.
one of the largest tracts of the brain stem.
in the telencephalon.
serotonergic.
in the mesencephalon
Which paradigm is illustrated here?

intracranial self-stimulation
conditioned place preference
contingent tolerance
drug self-administration
Pavlovian conditioning.
intracranial self-stimulation
The term "kicking the habit" refers to one of the symptoms of __________ withdrawal.

alcohol
nicotine
cocaine
opiate
marijuana
opiate
21. Convulsions and delirium tremens are caused by withdrawal from

morphine.
cocaine.
heroin.
alcohol.
high doses of nicotine.
alcohol
Olds and Milner argued that the brain circuits that support intracranial self-stimulation are the same ones that mediate

fear.
addiction.
the pleasurable effects of natural rewarding stimuli such as food, water, and sex.
withdrawal effects.
electroconvulsive effects.
the pleasurable effects of natural rewarding stimuli such as food, water, and sex.
The conversion of drugs in the body to nonactive chemicals is referred to as drug

tolerance.
metabolism.
withdrawal.
blocking.
habituation.
metabolism
Individuals who suffer drug withdrawal symptoms when they stop taking a drug are said to be

physically dependent.
psychologically dependent.
addicted.
both A and B
both B and C
physically dependent
Laboratory animals self-administer microinjections of addictive drugs directly into the

raphé nucleus.
nucleus accumbens.
basal forebrain.
hippocampus.
striatum.
nucleus accumbens.
Which of the following drugs is associated with severe dementia, gastritis, and cirrhosis of the liver?

alcohol
nicotine
morphine
cocaine
marijuana
alcohol
Which drug has been shown to increase the rate of cancer and heart disease in nonusers of the drug who are living with users of the drug?

alcohol
marijuana
tobacco
heroin
cocaine
tobacco
Which of the following drugs is a commonly prescribed analgesic?

morphine
caffeine
cocaine
alcohol
heroin
morphine
In addition to the nucleus accumbens, the prefrontal cortex, the hippocampus, and the amygdala are thought to play major roles in

the initial taking of addictive drugs.
drug tolerance.
the drug withdrawal syndrome.
drug sensitization.
severe chronic addiction.
the initial taking of addictive drugs.
Illustrated here is a paradigm that is used to study addictive drugs:
(mouse with "infusion pump" level in a box)

drug self-administration paradigm.
contingent tolerance paradigm.
conditioned place paradigm.
intracranial electrical self-stimulation paradigm.
conditioned tolerance paradigm
drug self administered paradigm
During cocaine sprees, there is a risk of

convulsions.
respiratory arrest.
stroke.
all of the above
none of the above
all of the above
The severity of withdrawal symptoms depends upon the

particular drug in question.
dose of the preceding drug exposure.
duration of the preceding drug exposure.
speed with which the drug is cleared from the body.
all of the above
all of the above
. Which of the following drugs in high doses produces a syndrome of psychotic behavior that is similar to paranoid schizophrenia?

alcohol
cocaine
heroin
opium
LSD
cocaine
Opiates likely exert their psychoactive effects by binding to

endorphins.
opiate receptors.
dopamine receptors.
both A and B
both A and C
opiate receptors
Restlessness, watery eyes, running nose, yawning, and sweating are all early signs of withdrawal from

alcohol.
opiates.
cocaine.
nicotine.
marijuana.
opiates
Sensitization is the opposite of

withdrawal.
physical dependence.
tolerance.
conditioned withdrawal effects.
addiction.
tolerance
. Pregnant females who use __________ risk bearing a child with physical deformities and mental retardation.

alcohol
nicotine
morphine
caffeine
marijuana
alcohol
According to the text, the sad truth about many heroin-related deaths is that many

heroin addicts suffer incredible pain before dying.
heroin addicts rarely take heroin.
appear to be caused in part by the very laws that were enacted to prevent them.
laws are aimed at solving the cause of the problem rather than the problem itself.
of those who die are not breaking the law.
appear to be caused in part by the very laws that were enacted to prevent them.
The branch of the mesotelencephalic dopamine system that projects from the ventral tegmental area is called the

mesocorticolimbic pathway.
tegmental-striate pathway.
medial forebrain bundle.
fornix.
nigrostriatal pathway.
mesocorticolimbic pathway.
Which of the following seem to share some brain mechanisms with drug addiction?

kleptomania
overeating
compulsive shopping
all of the above
none of the above
all of the above
Originally, the nucleus accumbens was thought to mediate the experience of reward, but some current evidence suggests that increases in extracellular dopamine occur in the nucleus accumbens when the

reward is administered.
subject expects the reward.
dopamine transporter is activated.
reward starts to be extinguished.
drug effects are experienced.
subject expects the reward.
65. Paradoxically, although rats typically press a lever at an extremely high rate to deliver electrical stimulations to their own septum or lateral hypothalamus, they
extinguish slowly.
extinguish rapidly.
sometimes have to be primed.
both A and C
both B and C
both b and c
(very broad picture of the brain)
Illustrated here is the location of the
nucleus accumbens.
substantia nigra.
ventral tegmental area..
nigrostriatal pathway.
all of the above
all of the above
63. Although the relevant evidence is far from convincing, libido-threatening reductions in testosterone, health-threatening reductions in immune function, cardiovascular problems, and amotivational syndrome have been attributed to the recreational use of

alcohol.

morphine.

cocaine.

marijuana.

nicotine.
marijuana
62. Many chronic addicts come to prefer the _______ route of drug administration
oral
IM
SC
IV
IP
IV
61. Drug addicts have been found to make poor decisions and to:
engage in excessive risky behavior.
make particularly poor decisions.
display deficits in self-control.
all of the above
none of the above
all of the above
60. As drug craving and compulsive drug taking develops, control of drug taking is thought to shift from the:
ventral to dorsal striatum.
prefrontal cortex to stress circuits in the hypothalamus.
septum to ventral tegmental area.
dorsal to the ventral septum.
both A and B
both A and B
59. Which of the following drugs is a stimulant?

heroin

morphine

cocaine

marijuana

both A and B
cocaine
58. Which of the following drugs is a diuretic?

alcohol

marijuana

nicotine

morphine

cocaine
alcohol
57. The severity of withdrawal symptoms depends upon the

particular drug in question.

dose of the preceding drug exposure.

duration of the preceding drug exposure.

speed with which the drug is cleared from the body.

all of the above
all of the above
56. Cirrhosis and Korsakoff's syndrome are two of the dire consequences of chronic __________ consumption.
Question 108 options:

nicotine

morphine

cocaine

marijuana

alcohol
alcohol
55. The Harrison Narcotics Act, which was passed in the U.S. in 1914, unintentionally encouraged the use of
Question 107 options:

Aspirin.

Street's Infant Quietness.

cocaine.

opium.

heroin.
heroin
The impure residue left after boiling away a solution of cocaine hydrochloride and baking soda is

crack.
smack.
lidocaine.
procaine
both A and B
crack
Which of the following is the strongest psychoactive ingredient of opium?

morphine
codeine
heroin
cocaine
methadone
morphine
Psychoactive drugs are those that affect

the activity of the central nervous system.
subjective experience.
behavior.
all of the above
psychotic behavior.
all of the above
Marijuana contains over 80

kinds of delta-9-tetrahydrocannabinol.
cannabinoids.
kinds of morphine.
kinds of Cannabis sativa.
hemp.
cannabinoids.
Freud died in 1939 from cancer caused by his addiction to

cocaine.
morphine.
nicotine.
alcohol.
marijuana.
nicotine
Currently, tobacco is implicated in about 1 of every __________ deaths in the United States:

5

37

50

100

400
5
Chronic use of which drug has been linked to bronchitis, emphysema, cancer, stroke, and heart attack?

alcohol

tobacco

cocaine

marijuana

morphine
tobacco
. A state of decreased sensitivity to a drug as a result of previous exposure to the drug is called
Question 104 options:

drug tolerance.

drug sensitization.

drug withdrawal.

physical dependence.

psychological dependence.
tolerance
A problem faced by many theories of drug conditioning is predicting

the direction of conditioned effects.

whether or not there is a conditional stimulus.

whether or not there is an unconditional stimulus.

whether conditioned or contingent tolerance will develop.

who will become addicted.
the direction of conditioned effects
Tolerance that occurs because the target tissue becomes less reactive to the drug after exposure is
Question 106 options:

situationally specific tolerance.

contingent tolerance.

reverse tolerance.

functional tolerance.

metabolic tolerance.
functional tolerance.
The case of Miss M. is interesting because
although she slept little, she appeared to be healthy, productive, and well adjusted.
her lack of sleep had rendered her neurotic.
she had, with considerable effort, trained herself not to sleep.
her lack of sleep caused her have vivid hallucinations during the day.
brain damage had left her unable to sleep.
although she slept little, she appeared to be healthy, productive, and well adjusted.
According to the incentive-sensitization theory of addiction, all addictive drugs produce

tolerance.
physical dependence.
sensitization to the effects that influence the pleasure produced by the drug.
sensitization to the effects that influence the positive-incentive value of the drug.
both A and B
sensitization to the effects that influence the positive-incentive value of the drug.
A key point of the incentive-sensitization theory of addiction is that

the positive-incentive value of addictive drugs habituates with use.
the pleasure-producing effects of addictive drugs are sensitized.
although the anticipated pleasurable effects of addicted drugs increase as the result of drug use, their actual pleasurable effects may not.
all of the above
both A and B
although the anticipated pleasurable effects of addicted drugs increase as the result of drug use, their actual pleasurable effects may not.
Individuals who experience drug withdrawal effects are, by definition,

addicted.
physically dependent.
metabolic.
tolerant.
psychologically dependent.
physically dependent
11. The EOG is a measure of

the first-night phenomenon.
eye-muscle tension.
eye movement.
stage 1 EEG.
both B and C
eye movement
Set-point theories of hunger and eating are inconsistent with

eating-related evolutionary pressures as we understand them.

the major effects on eating of taste, learning, and social factors.

the failure of researchers to confirm that energy deficits are the usual stimulus for eating.

all of the above

both B and C
all of the above
During the fasting phase, the body (excluding the brain) cannot use glucose as a metabolic fuel because


there is none left.

it is all stored in neurons.

insulin levels are low and insulin is needed for glucose to enter the cells of the body.

glycogen is needed for glucose to enter the cells of the body.

glucose is needed for insulin to enter the cells of the body.
insulin levels are low and insulin is needed for glucose to enter the cells of the body.
About __________ of the energy that a person uses each day goes to maintain her or his resting metabolic processes.

80%
70%
60%
50%
40%
80%
According to the text, anorexic patients - or anybody else who is severely undernourished - should not be fed

fats.
meals.
carbohydrates.
sweets.
proteins.
meals
It seems clear that warm-blooded animals that have ready access to a variety of palatable foods eat far more than is optimal for their health. Evidence of this point comes from

studies of the good health of humans who eat less than others.
experiments on the effects of calorie restriction in many different species.
experiments linking blood glucose with brain damage in human patients.
all of the above
both A and B
both A and B
The idea that the LH is a hunger center has largely been abandoned because:

bilateral lesions of the LH produce hyperphagia.

the paraventricular nucleus appears to be the hunger center.

bilateral LH lesions produce severe and general motor disturbances and reduce responsiveness to all kinds of sensory input.

LH lesions do not reduce eating.

LH lesions do not reduce either eating or drinking.
bilateral LH lesions produce severe and general motor disturbances and reduce responsiveness to all kinds of sensory input.
Evidence suggests that the hyperphagia of rats with large bilateral VMH lesions may be mediated by

sham eating.

intragastric feeding.

increases in insulin release.

hypoinsulinemia.

gluconeogenesis.
increases in insulin release
The transition between the absorptive and fasting phase occurs when

a person begins to weaken from lack of food. .

about 4 hours have passed since the last meal.

the body stops deriving its energy from the fuels still circulating in the blood from the previous meal.

the brain stops deriving its energy from glycogen.

the brain stops deriving its energy from the glycogen stored in neurons from the previous meal
the body stops deriving its energy from the fuels still circulating in the blood from the previous meal
Free fatty acids are the main source of energy for the body (excluding the brain) during

puberty.
infancy.
the fasting phase.
the cephalic phase.
the absorption phase.
the fasting phase
the dynamic phase of the VMH syndrome is associated with:

hypophagia
weight gain
lipgenesis
all of the above
both B and C
both b and c
Large bilateral lesions of the lateral hypothalamus produce:

aphagia
adipsia
hyperphagia
both A and B
both B and C
both A and B
Research has shown that naps have recuperative powers out of proportion with their:

power
frequency
brevity
positive incentive value
EEG
brevity
which of the following is least likely to result from sleep deprivation?

mood disturbances
reductions in creativity
reductions in vigilance
poor performance of complex cognitive tests
increased sleepiness
poor performance of complex cognitive tests
the melatonin released from the pineal gland is:

synthesized from dopamine.
exogenous
endogenous
both A and B
both A and C
endogenous
under free-running conditions, the correlation between the duration of a period of wakefulness and the duration of the following period of sleep was found to be:

negative
zero
slightly positive
positive
cyclic
negative
studies of encephalitis lethargica suggested that the ______ promotes wakefulness:

posterior hypothalamus
preoptic area
basal forebrain
both A and B
both B and C
posterior hypothalamus
volunteers who are allowed to sleep without interruption after several nights of REM deprivation tend to get:

almost no REM sleep
less REM sleep than usual
their normal amount of REM
significantly more REM sleep than usual
a lot of REM sleep even when they are awake
significantly more REM sleep than usual
Studies of electrical intracranial self stimulation have influenced the development of biopsychological theories of addiction by indicating that:

the rewarding effects of drugs play a major role in addiction

there are particular areas of the brain that mediate the experience of pleasure

drug withdrawal and drug pleasure are opposite processes

there are particular areas of the brain that mediate pleasure from drugs

the brain mediates pleasure
there are particular areas of the brain that mediate the experience of pleasure
the early physical-dependence theories of drug addiction were discredited by the observation that:

detoxified addicts almost always return to their drug-taking habits

if addicts withdraw over a long period, withdrawal symptoms are more severe

drug addicts who are kept form using drugs for a year or more almost always permanently kick the habit

both A and B

both B and C
detoxified addicts almost always return to their drug-taking habits
the before and after design is often used to demonstrate:

contingent tolerance
metabolic tolerance
situationally specific tolerance
functional tolerance
reverse tolerance
contingent tolerance
Many chemicals are kept from passing from the circulatory system of the CNS into CNS neurons by

reflexology.
tolerance.
the blood-brain barrier.
the cerebrospinal fluid.
withdrawal.
the blood-brain barrier
Drug injection is common in medical practice because the effects of injected drugs are relatively __________ in comparison to most other conventional routes of drug administration.

minor
rapid
predictable
all of the above
both B and C
both B and C
Many researchers believe that a major cause of drug relapse is

priming.
stress.
drug-related cues.
all of the above
none of the above
all of the above
Which of the following routes of drug administration offers the least opportunity to counteract the effects of an overdose?

IV
IM
SC
through mucus membranes
oral
IV
Which country has taken a novel approach to the problem of heroin addiction, an approach that is proving to be an unqualified success?
Question 10 options:
Canada
Switzerland
USA
England
Germany
Switzerland
Evidence that the nucleus accumbens is involved in drug addiction comes from reports that
Question 11 options:
animals will self-administer microinjections of addictive drugs directly into the nucleus accumbens.
microinjection of addictive drugs into the nucleus accumbens can lead to the development of conditioned place preferences..
lesions to the nucleus accumbens reduce the rewarding effects of systemic drugs.
all of the above
both A and C
all of the above
The animal model that best approximates human drug addiction is the
Question 12 options:
conditioned tolerance model.
contingent tolerance model.
drug self-administration paradigm.
drug withdrawal syndrome
conditioned place preference paradigm.
drug self-administration paradigm.
Evidence indicates that one common health hazard of chronic marijuana smoking is
Question 13 options:
brain damage.
lowered testosterone levels in males.
bradycardia.
cancer.
respiratory dysfunction.
respiratory dysfunction.
Most laws governing drug abuse were enacted

in the early 1900s or before.
before there was relevant scientific information.
in the 1960s.
both A and B
both B and C
both A and B
Taking one drug can often produce tolerance to other drugs; such tolerance is called

generalized tolerance.
cross tolerance.
contingent tolerance.
functional tolerance.
transferred tolerance.
cross tolerance.
These drugs are widely used in the treatment of pain, cough, and diarrhea:

anxiolytics.
stimulants.
opiates.
depressants.
antidepressants.
opiates
During the fasting phase, most of the energy used by muscles is derived from

glucose.
free fatty acids released from adipose tissue..
glycogen.
amino acids.
ketones.
free fatty acids released from adipose tissue
Inconsistent with set-point theories of hunger and eating is the fact that

flavor has a major impact on hunger and eating.
the brain can use ketones.
the main fuel of the brain is glucose.
humans are warm-blooded.
men weigh more than women.
flavor has a major impact on hunger and eating.
Mutant ob/ob mice...

have high leptin levels.
tend to be obese.
are heterozygous for the mutant gene.
all of the above
both A and B
tend to be obese
As we fall asleep,

alpha activity begins.
EMG activity suddenly increases.
alpha activity ceases.
REMs begin to occur.
REMs suddenly stop.
alpha activity ceases
A polyphasic sleep cycle is one in which the individual regularly sleeps:

once every 24 hours.
once every 24 hours, but sometimes in the day and sometimes in the night.
more than once every 24 hours.
three times or more every 24 hours.
in two or more different advanced phases.
more than once every 24 hours.
During REM sleep, changes in autonomic nervous system activity suggest:

arousal.
unresponsiveness.
increased relaxation.
neural inactivity.
both B and C
arousal
It is difficult to compare lever pressing for food reinforcers with lever pressing for brain stimulation because in most self-stimulation studies, the:

subjects are not deprived.
lever press delivers the reinforcement directly without the necessity of an intervening consummatory response.
subjects are tested without reinforcement.
subjects are rats.
both A and B
both A and B
Exercise programs for the obese have proven to be relatively ineffective in promoting weight loss. This surprising result is likely attributable to the fact that
both A and B:

the majority of the body's calorie expenditure is dedicated to maintaining the physiological processes of the body rather than fueling behavior.

after exercising; many people consume extra drinks and food that offset their calorie loss.
Animals in the wild tend to eat a balanced diet because they
none of the above
none of the above
Those mammals with ready access to a continuous supply of good food usually eat __________ per day
many small meals or snacks
Small amounts of food eaten prior to a meal __________ hunger. This is called __________
increase, the appetizer effect
The three phases of energy metabolism are, in sequence,
cephalic, absorptive, and fasting.
Many people believe that hunger is a product of
energy deficits
According to the default theory, REM sleep and wakefulness
are similar
After a person falls asleep at night, the fourth stage of sleep EEG that is normally observed is
stage 4
In one study, volunteers gradually reduced the number of hours that they slept each night, until they felt that they had reached their limit. On the average, this limit was
5 hours.
The EEG of the encephale isolé preparation is almost continuously:
none of the above
A condition in which a person's sleep is repeatedly disrupted by the inability to breath is called
sleep apnea
The encephale isolé preparation is produced by transecting the
caudal brain stem
Which of the following is a finding about addiction that is currently influencing the study of its brain mechanisms?
all of the above
Medical examiners often attribute death to heroin overdose without assessing blood levels. In one study, careful toxicological analysis at autopsy of such cases often revealed

low blood levels of heroine
high blood levels of other CNS depressants such as alcohol and benzodiazepines
high levels of disulfiram
both A and B
both A and C
both A and B
According to Ramsay and Woods, the unconditional stimulus in drug conditioning experiments is
the disruption of neural functioning that is directly produced by the drug.
The main disadvantage of the oral route of drug administration is
its relative unpredictability
Withdrawal from which of the following drugs has been likened to a bad case of the flu?
opiates
Morphine is an

analgesic.
opiate.
endogenous opiate.
both A and B
both A and C
both A and B
Which does not belong with the others?
dreaming
emergent stage 1 EEG
REM
initial stage 1 EEG
loss of core muscle tone
initial stage 1 EEG
Neurons of the nucleus magnocellularis
normally control muscle relaxation during REM sleep.
are active during attacks of cataplexy.
are the only cells of the caudal reticular formation that are not active during epileptic attacks.
both A and B
both B and C
both A and B
Species that sleep a lot tend to

be more active.
have higher body temperatures.
be small.
be invulnerable to predation when they sleep.
all of the above
be invulnerable to predation when they sleep.
Hunger and eating can be induced in satiated mammals by decreasing blood glucose levels with large injections of insulin. However, such large decreases

rarely, if ever, occur in healthy humans or other mammals with ready access to food.

occur naturally about four times per day in humans.

occur naturally about three times per day in most mammals.

occur naturally just before mealtime in North Americans, who are used to eating three meals per day.

occur six times per day in humans--on the average.
rarely, if ever, occur in healthy humans or other mammals with ready access to food.
Koopmans transplanted a stomach from one rat into another and connected the circulatory system of the transplant to that of the recipient. He then injected food into the implanted stomach. This experiment indicated that

the gastrointestinal tract produces a satiety signal.

food-related chemical signals from the stomach are transmitted through the circulatory system to the brain.

nutrients from the stomach are transmitted through the circulatory system to the brain.

both A and B

both A and C
both A and B
If you were to eliminate 500 calories from your daily diet, you would likely

lose a constant amount each day until you stopped losing weight.

automatically decrease your exercise, and your weight would stay about the same.

initially lose weight, but the amount lost each day would decline until a new stable weight was reached.

produce less heat and lose no weight.

keep losing weight until you terminated your diet.
initially lose weight, but the amount lost each day would decline until a new stable weight was reached.
Most studies and personal experiences of sleep deprivation are confounded by
Question 91 options:
stress.
dreaming.
energy deficits.
circadian rhythms.
sleep walking.
stress
There is more than one circadian clock. Early evidence for this was that bilateral lesions of the

suprachiasmatic nuclei abolish all circadian rhythms.

suprachiasmatic nuclei do not abolish circadian rhythms.

raphé nucleus abolish sleep.

raphé nucleus abolish wakefulness.

suprachiasmatic nuclei increase sleep.
suprachiasmatic nuclei do not abolish circadian rhythms.
REMs are associated with

initial stage 1 EEG.
increased EMG activity in the core muscles.
stage 4 EEG.
emergent stage 1 EEG.
the first-night phenomenon.
emergent stage 1 EEG.
Which of the following are commonly prescribed as hypnotics?

barbiturates
tricyclic antidepressants
benzodiazepines
serotonin antagonists
melatonin
benzodiazepines
A hangover is a
Question 102 options:
mild withdrawal syndrome.
form of alcohol psychosis.
fetal syndrome.
form of dementia.
sensitization effect.
mild withdrawal syndrome.
The "high" experienced by cocaine users was found in one study to be related to the degree of binding of the cocaine to
Question 103 options:
dopamine transporters.
dopamine autoreceptors.
serotonergic receptors.
dopamine receptors.
nucleus accumbens neurons.
dopamine transporters.
"Song of Praise" to cocaine was written by
Question 109 options:
The Grateful Dead.
Bob Marley.
Paul Simon.
The Rolling Stones.
Sigmund Freud.
Sigmund Freud.
In the United States, about __________ million people are addicted to nicotine, alcohol, or both.
Question 2 options:
1
2.5
5
10
60
60
The main psychoactive ingredient of coca paste is
Question 6 options:
cacao.
crack.
cocaine hydrochloride.
lidocaine.
procaine.
cocaine hydrochloride.
Attempts to treat heroin and morphine addiction often involve the prescription of
Question 11 options:
methadone.
heroin.
morphine.
all of the above
both B and C
methadone
Most drugs that are taken orally enter the bloodstream through the walls of the
Question 16 options:
stomach.
mouth.
intestine.
esophagus.
lungs.
intestine.
Which of the following opiates is an analgesic?
Question 17 options:
morphine
codeine
amphetamine
all of the above
both A and B
both A and B
Song of Praise" was written by Freud about
Question 23 options:
nicotine.
cigars.
his female companion.
cocaine.
heroin.
cocaine
Many self-stimulation sites contain
Question 25 options:
serotonergic neurons.
dopaminergic neurons.
dopamine agonists.
glutamate receptors.
dopamine antagonists
don't know
Grossly obese rats with large bilateral VMH lesions often
eat less than unlesioned rats.
are unwilling to work for food.
will not eat food that is slightly unpalatable.
all of the above
both B and C
both b and c
After reviewing the research literature on nightly sleep reduction and trying it himself, the author of your text, concluded that

most people need at least 8 hours of sleep per night.
many people can reduce their sleep to about 5.5 hours per night with no serious adverse effects other than day-time sleepiness when they are sedentary.
there is no need to sleep, and there are no negative consequences of sleep reduction.
sleep is primarily recuperative, and we should always get as much sleep as we can, especially if a doctor tells us to.
all people should sleep 5.5 hours per night.
many people can reduce their sleep to about 5.5 hours per night with no serious adverse effects other than day-time sleepiness when they are sedentary.
According to the dominant hypothalamic theory of eating in the 1950s and 1960s, hunger is to satiety as the..

LH is to the VMH.
VMH is to the LH.
LH is to the paraventricular nuclei.
pancreas is to the liver.
paraventricular nuclei are to the LH.
LH is to the VMH
The level at which the various factors that influence body weight achieve an equilibrium is called the body weight

set point.
settling point.
water level.
cephalic level.
leaky barrel.
settling point
Set-point, negative-feedback systems are one way of maintaining

high levels of food intake.
high levels of body fat.
high levels of energy consumption.
high levels of hunger.
homeostasis.
homeostasis
The set-point theory of body weight regulation is designed to explain

fluctuations in body weight.
how the weights of adults stay constant.
the relation between glucostatic and lipostatic theories.
how peptides promote satiety.
why obesity is so prevalent.
how the weights of adults stay constant.
Which of the following produces a substantial increase in the caloric intake of laboratory rats and a significant increase in their body weight?

removing thiamine from their usual laboratory chow
adding thiamine to their usual laboratory chow
offering them a cafeteria diet, rather than their usual laboratory diet
sham feeding them
both C and D
offering them a cafeteria diet, rather than their usual laboratory die
Cafeteria diets

greatly reduce consumption.
maintain consumption at baseline levels.
are those in which several palatable foods are available.
are inherently less healthy.
increase sensory-specific satiety.
are those in which several palatable foods are available.
One of the first studies of the physiology of hunger was that of Cannon and Washburn (1912). They found that:

subjective feelings of hunger are associated with stomach contractions.
subjective feelings of hunger are associated with eating.
stomach contractions are associated with high blood glucose levels.
stomach contractions are associated with eating.
eating is associated with high blood glucose levels.
subjective feelings of hunger are associated with stomach contractions.
The EEG of a cerveau isolé is desynchronized only during

sleep.
wakefulness.
intense visual or olfactory stimuli.
all of the above
both A and C
intense visual or olfactory stimuli.
In Kleitman's classic studies of sleep deprivation, student volunteers grew steadily more __________ as the period of deprivation grew longer.

sleepy
incapable of performing intelligence tests
unable to stay awake
all of the above
none of the above
none of the above
Melatonin appears to be effective in treating:

insomnia that results from a melatonin deficiency.

hypersomnia.

insomnia that results from the failure of light to serve as a zeitgeber in blind patients.

both A and C

both B and C
both A and C
Most studies and personal experiences of sleep deprivation are confounded by

stress.
dreaming.
energy deficits.
circadian rhythms.
sleep walking.
stress
According to the text, which theory of sleep does the best job of explaining why there are such large differences in the amount of time that the members of various mammalian species spend sleeping?

recuperative theory
Freudian theory
adaptation theory
activation-synthesis theory
sandman theory
adaptation theory
Which of the following animals spend about 14 hours per day sleeping?

cows
horses
giant sloths
cats
deer
cats
In the entire week after being totally deprived of sleep for 11 days, Randy Gardner slept a total of about __________ hours more than usual.

6
18
22
34
54
6
Each cycle of sleep during the night tends to be about

5 minutes long.
20 minutes long.
35 minutes long.
90 minutes long.
140 minutes long.
90 minutes long.
Which of the following is a causal factor in some cases of insomnia?

sleeping pills
sleep apnea
nocturnal myoclonus
restless legs
all of the above
all of the above
Theories postulating that sleep permits the body to recover from internal deficits produced by wakefulness are often referred to as:

adaptation theories.
recuperation theories.
free-running theories.
circadian theories.
diurnal theories.
recuperation theories.
In one study, 8 volunteers reduced their sleep by 30 minutes per night until they did not want to reduce it further. A major finding was that:

4 managed to reduce their sleep to 5 hours per night.
2 managed to reduce their sleep to 4.5 hours per night.
the volunteers began to experience significant daytime sleepiness once they had reduced their sleep to 6 hours or less per night.
the volunteers were still sleeping between 7 and 18 hours less per week when they were tested 1 year later.
all of the above
all of the above
The pineal gland is located on the midline just below the posterior portion of the
Question 19 options:
corpus callosum.
hypothalamus.
cerebellum.
amygdala.
hippocampus.
corpus callosum.
The association of REM sleep and dreaming was discovered in the early 1950s in the laboratory of

Siegel.
Kleitman.
Mistlberger.
Meddis.
Freud.
Kleitman
The first mammalian circadian gene to have its structure characterized was

tau.
clock.
alarm.
circa.
circada
clock