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19 Cards in this Set
- Front
- Back
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4 roles of fatty acids?
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1. source of bodys energy
2. building blocks of membranes 3. covalent modification of proteins 4. serve as hormones/messengers |
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ultimate fate of f.a. degradation is?
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acetyl coA
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F.a. are highly concentrated energy source because
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they are reduced and anhydrous
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Our dietary lipids are in the form of?
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triacylglycerols
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triacylglycerols are degraded into what by what enzyme?
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fatty acids and monoacylglycerol by lipases from pancreas
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Once resynthesized from f.a. and monoacylglycerol, triacyglycerols bind to what to transport them?
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chylomicrons
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lipases are activated by what/
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binding of glucagon and or epinephrine which results in CAMP cascade
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F.a. degredation begins with the f.a. esterified to acetyl coA by what enzyme
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acyl CoA sythetase
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after acyl coa formed, transport acros mitochondrial membrane occurs how?
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fatty acyl coa are conjugated to carnitine to form an acyl carnitine intermediate.
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this uses what enzyme/
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acyl carnitine transferase I
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After entry into mito. matrix, reesterfication to CoA occcurs by what enzyme
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acyl carnitine transferase II
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the four steps of fa oxidation/degredation are?
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oxidation by FAD, hydration, oxidation by NAD, and thiolysis by CoA.
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fatty acyl coa to trans enoyl CoA is catalyzed by what?
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acyl coA dehyrdrogenase
(uses FAD) |
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what are the two accessory enzymes used for unsaturated fatty acid degredation?
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cis 3 enoyl coA isomerase and 2,4 dienoyl CoA reductase
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Odd chain unsaturations require?
Even require? |
cis 3 enoyl coA isomerase; isomerase and 2,4 dienoyl coA reductase
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f.a. oxidation/degredation occurs where?
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in mitochondria
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f.a. synthesis occurs?
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cytoplasm
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When does acetyl coA from f.a. oxidation enter the TCA cycle
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only when fat and carbohydrate breakdown are balanced
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oxidation of acetyl coA through TCA cycle is dependent on what?
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availability of oxaloacetate which is dependent on supply of carbohydrates
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