• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

Card Range To Study



Play button


Play button




Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

15 Cards in this Set

  • Front
  • Back
what takes place in mitochondria?
almost all oxygen is consumed there and almost all phosphorylation of ADP to ATP
where do mitochondria exist
sub-sarcolemmal - provide energy to maintain cell membrane processes
Intermyofibrillar - play a major role in maintaining ATP for contraction
what is the general structure of mitochondira
outer membrane, intermembrane spaces, inner membrane, cristae, matrix
function of outer membrane?
barrier that contains transport mechanisms
function of intermembrane spaces?
contains enzymes for exchange and transport
function of cristae?
where oxidative phosphorylation takes place
function of matrix?
contains LDH and kreb's cycle enzymes
what is the role of PDH?
it regulates glycolytic flux into mitchondria (TCA cycle)
converts pyruvate to Acetyl - CoA
what is the main purpose of the Krebs cycle and what is the rate limiting factor?
the main purpose is decarboxylation (CO2 formation), ATP formation, and most importantly NADH production, one FADH is also produced
isocitrate is rate limiting
what stimulates dehydrogenase enzymes of the TCA?
calcium from contraction that is taken up by mitochondria and a decline in redox potential
what are the two steps of processes of oxidative phosphorylation?
1. stripping the electron from the reducing equivalents of NADH and FADH
2. the chemical and osmotic potential created by this supplies the energy for phosphorylation which results in ATP and H2O formation
what regulates the ETC?
adenylate energy charge - regulates glycolysis and krebs cycle
ATP inhibits and ADP stimulates
what is the creatine phosphate shuttle?
buffers ATP degradation which results in ATP and creatine formation
creatine is rephosphorylated by mitochondrial creatine kinase which results in ADP formation which stimulates ATP formation and oxygen consumption
how much ATP is formed from glucose oxidation?
anaerobic conditions - 2 ATP
aerobic conditions - 2 ATP and 2 NADH shuttled to mitochondria net 4-6 ATP
2 3-C skeletons in TCA cycle at 15 ATP per round
therefore net 36-38 ATP/glucose molecule
only 3 ATP if it arises from glycogen
what are the effects of training on skeletal muslce mitochondria?
trained muscle has more mitochondrial material which allows a given rate of mitochondrial O2 consumption at a higher ATP/ADP therefore downregulates glycolysis and increases lipid oxidation