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162 Cards in this Set
- Front
- Back
All somatic cells contain ____ chromosomes
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46
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Union of a normal egg or sperm with one that contains an extra chromosome – down syndrome is most common = 47 chromosomes
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Trisomy
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When a normal gamete unites with one that is missing a chromosome=45
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Monosomy
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Condition in which one of the 2 X chromosomes becomes inactive (female)
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Barr Body
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Genes responsible for observable expressions (brown eyes, dark skin)
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Phenotype
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Total genetic makeup
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Genotype
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Earlier diagnostic test (8-12 weeks gestation)
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Chorionic Villus Sampling (CVS)
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Allows for rapid chromosome dx, genetic studies or transfusion for Rh isoimmunization
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Percutaneous Umbilical Blood Sampling (PUBS)
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Elevated in infants w/ open neural tube defect, anencephaly, omphalocele, gastroschisis, or multiple gestation
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Alpha Fetoprotein (AFP & AFP3)
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Ashkenazi Jewish (at risk for which specific disorder)
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Tay-Sachs Disease
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African; Hispanic from Caribbean, Central/South Americas (at risk for which specific disorder)
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Sickle Cell Anemia
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Greek, Italian (at risk for which specific disorder)
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beta-thalassemia
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SE Asia - Vietnamese, Laotian, Cambodian, Philippine (at risk for which specific disorder)
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alpha-thalassemia
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Women over age 35 (at risk for which specific disorder)
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Chromosomal trisomies
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Subjective changes in pregnancy
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amenorrhea,
N/V (r/t increase hCG and change in carb metabolism) aka morning sickness urinary frequency excessive fatigue breast tenderness quickening (perception of fetal movement 18-20wks) |
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Softening of the cervix
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Goodell's Sign
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Vagina, cervix, and vulva with purplish discoloration
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Chadwick's sign
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Softening of uterine isthmus (6-8 weeks)
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Heger's sign
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Soft spot anteriorly in the middle of the uterus
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Ladin's sign
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An ease in flexing the body of the uterus against the cervix
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McDonald's sign
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5th week - Irregular softening & enlargement at site of implantation
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Broun von Fernwald's sign
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Occasional almost tumor-like asymmetric enlargement
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Piskacek's sign
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Soft blowing sound at pulse rate on auscultation
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Uterine Soufflé
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Passive fetal movement by pushing up against the cervix with 2 fingers
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Ballottement
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Reproductive system changes
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uterine growth
amenorrhea suppression of FSH cervical & vaginal changes color & production of colostrum |
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Integumentary changes
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striae gravidarum
separation of rectus muscles melasma or chloasma |
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Respiratory changes
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SOB in late pregnancy
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Temperature changes
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increase due to progesterone secretion
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Cardiovascular changes
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increased blood volume (30%)
increased cardiac output (25-50%) increased HR by 10 |
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GI Changes
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N/V
heartburn increased saliva |
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Urinary changes
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fluid retention
change in renal, ureter, & bladder function |
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Hormonal Changes
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increased estrogen & progesterone cause thickening of uterine walls
cervix cells proliferates & secretes thick, tenacious mucus |
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The expectant father develops physical symptoms of pregnancy: fatigue, depression, HA, backache, and nausea
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Couvade Syndrome
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Nagele's Rule
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First day of last menses, subtract 3 months, add 7 days
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Common Discomforts During 1st Trimester
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Leukorrhea (high risk for yeast infection)
Nasal stuffiness & Epistaxis Ptyalism (excessive often bitter saliva) |
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Common Discomforts During 2nd & 3rd Trimesters
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Heartburn
Ankle edema Varicose Veins Leg Cramps Carpal Tunnel Syndrome |
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When to administer rubella vaccine for pregnant patient?
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Until after birth
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Reason for taking pre-natal vitamins
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Prevent neural tube defects (folic acid)
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Pre-term labor MgSO4 dose
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Loading: 4-6g over 30 minutes
Maintenance: 2-4g/hr |
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Pre-eclampsia MgSO4 dose
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Loading: 6g IV over 15 minutes
Maintenance: 2g/hr |
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Ritodrine
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Relaxes uterine muscle through beta-2 receptor sites
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Terbutaline sulfate
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to maintain uterine inactivity
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Betamethasone sodium phosphate (Celestone)
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corticosteroid administered to accelerate lung surfactant formation in the fetus. (Takes 24 hours to be effective)
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Recommended total weight gain for Normal BMI
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25-35 lbs
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Excessive vomiting - can progress to dehydration, electrolyte imbalance, acidosis, wt loss, ketonuria, hepatic & renal damage (rare)
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Hyperemesis gravidarum
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Tubal damage r/t PID, previous pelvic or tubal surgery, endometriosis, IUD (50% of cases referred shoulder pain
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Ectopic Pregnancy
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Hydatidiform mole - molar pregnancy - abnormal development of the placenta resulting in fluid filled grapelike clusters & trophoblastic tissue proliferates
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Gestational trophoblastic disease (GTD)
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Placenta is improperly implanted in lower uterine segment
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Placenta Previa
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Premature separation of a normally implanted placenta
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Abruptio Placentae
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Painless dilation of the cervix without contraction
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Incompetent Cervix
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Dx of chorioamnionitis in 10% of cases
Responsible for 1/2 of all preterm babies |
Premature Rupture of Membranes (PROM)
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Labor that occurs between 20-37 weeks
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Preterm labor
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Most common developement of HTN, proteinuria, and edema
Define as increase in SBP of 30 mmHg or DBP of 15mmHg |
Pre-eclampsia
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Convulsion - high risk for seizure or coma
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Eclampsia
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When BP is 140/90 or higher before pregnancy or before 20th week
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Chronic Hypertensive Disease
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When transient elevation of BP occurs during labor or in early post-partal period, returning to normal within 10 days postpartum
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Later or Transient HTN
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An antigen-antibody immunologic reaction within the body
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Rh Sensitization
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TORCH
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Toxoplasmosis
Rubella Cytomegalovirus Herpes simplex virus |
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Indicator of fetal well-being (AFV and AFI)
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Amniotic Fluid Assessment
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*****: Breathing movement, body movement, tone, AFV, and FHR
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Biophysical Profile
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Study of non-invasive blood flow changes
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Doppler Velocimetry
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Spontaneous or induced by Oxytocin, test evaluates placental function & fetal health
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Contraction Stress Test
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Assesses FHR related to fetal movement
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Non-Stress Test
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Can make chromosomal & biochemical determinations as early as 1-18 weeks
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Amniocentesis
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Test that allows for rapid chromosome dx
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Percutaneous Umbilical Blood Sampling
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Refers to relation of the fetal parts to one another
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Fetal Attitude
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Relationship of the cephalocaudal axis of fetus to that of mother
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Fetal Lie
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Most common fetal position
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LOA (Left, occipito-anterior)
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Second most common fetal position
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ROA (Right, occipito-anterior)
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When the largest diameter of the presenting part reaches or passes through the pelvic inlet
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Engagement
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Relationship of the presenting part of the imaginary line between the ischial spines of the maternal pelvis
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Station
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Landmark on the presenting fetal part to the front, back, or sides of the maternal pelvis
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Fetal Position
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Uterine muscular contractions which cause the changes in the 1st stage of labor - complete effacement & dilation of the cervix
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Primary Force
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Use of abdominal muscles to push during the 2nd stage of labor
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Secondary Force
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3 Phases of Contractions
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Increment
Acme (peak) Decrement (letting up) |
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Time between beginning of one to the beginning of next contraction
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Frequency of contractions
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Measured from the beginning of the contraction to the end of said contraction
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Duration
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Strength of the contraction
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Intensity
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Labor that produces progressive dilation & effacement of the cervix
Contraction intervals are regular & gradually shorten |
True Labor
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Irregular, intermittent contractions, may be uncomfortable & exhausting
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Braxton Hicks
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Fetus settles into pelvic inlet - mother can breathe more easily
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Lightening
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Softening of the cervix
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Ripening
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Begins with contractions & ends with fully dilated cervix (10cm)
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First stage of labor
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Onset to rapid cervical dilatation (1-4cm), contractions every 10-30 min, 10-20 sec duration
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Latent Phase
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Cervical dilation 4-7 cm. Stronger contractions lasting 40-60 sec every 2-3 minutes
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Active Phase
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Maximum dilation 8-10 cm - Contractions reach their intensity, complete cervical effacement. Phase ends with irresistible urge to push
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Transition Phase
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Full dilation to birth of infant. Crowning to pushing the fetus out of the birth canal
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Second Stage of Labor
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Begins with expulsion of the infant & placenta
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Third Stage of Labor
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1-4 hours after expulsion of placenta
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Fourth Stage of Labor
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Viewed as normal, normally occurs late in labor when the head is fairly low, represents pressure on the fetal head during contractions
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Early decelerations
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Delayed 30-40 sec after contraction onset & continue after contraction. Suggests uteroplacental insufficiency or decreased blood flow
Interventions? |
Late decelerations
Maternal position should be lateral, slow/stop oxytocin, administer O2 and prepare for prompt delivery |
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Unpredictable and indicates compression of the cord.
Interventions? |
Variable decelerations
Change position to lateral or trendelenberg, administer O2, possible amnioinfusion with NS or LR |
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Sluggish contractions, dysfunctional labor
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Inertia
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Artificial rupturing of membranes with woman in dorsal recumbent position
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Amniotomy
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Surgical incision of perineum done to allow fetal head to pass, preventing a tear to the perineum
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Episiotomy
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Artificially starting laborat term.
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Induction
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Disk-shaped cup pressed against the fetal scalp to help pull fetus out
Can cause marked caput (contraindicated in pre-term) |
Vacuum
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Medication to soften cervix to prepare for labor induction
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Prostaglandins
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Synthetic form of posterior pituitary hormone used to initiate uterine contractions
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Oxytocin
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Return of reproductive organs to pre-pregnancy size & condition
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Involution
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Descends @ 1cm/day for 10 days after birth.
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Fundal Descent
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Organ that regains its shape by 18 hours after birth
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Cervix
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Lochia Rubra
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First 3 days, mostly blood with pieces of decidua and mucus
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Lochia Serosa
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4th day amount decreases and color changes to pink/pinkish brown
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Lochi Alba
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After 10th day discharge becomes yellowish white (may last for 6 weeks or more)
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Mother's need for food, fluid, & sleep. Phase of nurturing & protective care
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Taking-in phase
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Mother becomes more independent & takes responsibility for her care & shifts focus to the care of the infant (@10 days)
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Taking-hold phase
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Role change from carefree lifestyle to being on a couple. The parents move forward as a unit with a new member
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Letting-go phase
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Difficult labor - most common is dysfunctional uterine contractions that result in a prolongation of labor
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Dystocia
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Rapid labor & birth within 3 hours
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Precipitate Labor & Birth
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Pregnancy that extends more than 294 days or 42 weeks
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Post-term pregnancy
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Occiput-posterior position - causes mother severe pain
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Fetal Malposition
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Forehead becomes the presenting part, head slightly extended instead of flexed
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Brow Presentation
C-Section necessary |
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Most common malpresentation
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Breech Presentation
Emergency C-Section |
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Weight of more than 4000 g (8lb 14oz)
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Macrosomia
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One or more accessory lobes of fetal villi will develop on the placenta
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Succenturiate Placenta
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Double fold of chorion & amnion form a ring around cord on fetal side
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Cicumvallate placenta
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Umbilical cord is inserted at or near the placental margin
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Battledore placenta
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Vessels of the cord divide some distance from the placenta
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Velamentous insertion of the umbilical cord
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Bolus of amniotic fluid enters the maternal circulation & cord is compressed
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Amniotic Fluid Embolism/Anaphalactoid Syndrome of Pregnancy
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Occurs when there is > 2000ml of amniotic fluid during 2nd half of pregnancy
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Hydramnios
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Turning the fetus
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Version
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Presentation is changed from breech to cephalic by externa manipulation of the abdomen
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External cephalic version (ECV)
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Obstetrician places hand inside uterus & turns from transverse
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Internal version or podalic
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Technique where a volume of warmed, sterile NS or LR is introduced in to the uterus to increase the volume of fluid
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Amnioinfusion
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Covers the preterm newborn
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Vernix
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Flexing the baby's hand toward the ventral forearm until resistance is felt - angle is measured
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Square window sign
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Test of flexion development
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Recoil
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Degree of knee flexion
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Popliteal angle
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Placing the baby in supine & drawing an arm across the chest
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Scarf sign
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Gently drawing the foot toward the ear
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Heel to ear extention
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Infant turns head to side when corner of mouth is stroked
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Rooting
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Elicited by touching the newborn's lips
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Sucking
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Infant forces the tongue outward when the tip is depressed or touched
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Extrusion
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Fingers flex & grasp a finger placed across their palm
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Palmar grasp
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Fencing reflex - flexing & extension of limbs dependent of turning of the head
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Tonic neck
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Startle reflex - response may be asymmetrical due to injury of the clavicle, humerus, or brachial plexus
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Moro reflex
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An infant lying prone will turn shoulder & pelvis to the stimulated side when skin near spine is stroked
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Gallant reflex
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Stroking the plantar surface of an infants food upward causes great toe dorsiflexion
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Babinski's Reflex
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Bluish dsicoloration of hand & feet
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Acrocyanosis
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Lacy pattern of dilated blood vessels under the skin
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Mottling
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Color change, deep color develops over one side while other side remains pale
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Harlequin sign
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Evaluated by blanching the tip of the nose, forehead, or gum line
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Jaundice
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Firm lesion 103 cm whtie or pale yellow papule
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Erythema Toxium
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Exposed sebaceous glands - raised white spots on face
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Milia
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White cheese-like substance
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Vernix caseosa
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Blood between the periosteum of the skull bone & bone itself due to ruptured capillaries at birth
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Cephalhematoma
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Edema of scalp at the presenting part of the babies head - crosses suture line
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Caput succedaneum
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Normal neonate BP
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60/40
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Normal neonate pulse
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120-160, >180 if crying
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Normal neonate respirations
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30-60
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Vitamin K (AquaMEPHYTOIN) given why?
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To prevent hemorrhage d/t low prothrombin levels
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Why apply ophthalmic oint to neonates eye?
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Prophylaxis against Chlamydia
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S/S of Neonatal Distress
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Sternal retractions, nasal flaring, grunting excessive mucus, cyanosis, vomiting of bile, absence of meconium, and temp instability
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yellowish or creamy fluid thicker than later milk, and contains more protein, fat-soluble vitamins & minerals, high levels of antibodies
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Colostrum
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Recurrence of ovulation & menstruation?
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non-nusring mothers 7-9 weeks
90% resume in 12 weeks |
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A mild, transient condition in which mother cries for no apparent reason, fatigued, anxiety, restlessness, letdown feeling
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Postpartum blues
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Serious, intense persistent feelings characterized by inability to feel loved, irritability, guild, shame, disinterest in infant, and thoughts of harming infant
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Postpartum depression
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Rhogam
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Given within 72 hours of birth to prevent sensitization of Rh negative moms who have given birth to Rh positive infants
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Uterus Compresses the aorta & vena cava when mother is supine, decreasing fetoplacental blood flow
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Venal Caval Syndrome - Change position of mother, elevate one hip in side-lying position
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What should you keep at bedside if administering Mg Sulfate?
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Calcium gluconate
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Gravida TPAL
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G: # of pregnancies regardless of duration
T: # of term infants P: # of preterm infants A: # of pregnancies ending in abortion L: # of currently living children |