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27 Cards in this Set
- Front
- Back
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How are the Rh antigens inherited?
A) X-linked recessive B) codominant alleles C) X-linked dominant D) none of the above |
B) codominant alleles
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In the MN blood group system, a person who inherits an "M" allele and "N" allele expresses both M and N antigens on the red blood cells. Which of the following is true?
A) M is dominant to N B) N is dominant to M C) M an N are codominant alleles D) M and N are located on the same chromosome |
C) M an N are codominant alleles
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What is the source of anti-A1 lectin?
A) Bandeiraea simplicifolia B) Dolichos biflorus C) Ulex europaeus D) all of the above |
b) dolichos biflorus
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Most Rh antibodies are of what immunoglobulin class?
A) IgM B) IgG C) IgA D) IgE |
b) IgG
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Which of the following unit/s is/are appropriate for neonatal exchange transfusions?
A) group A RBC, A FFP, CMV-negative B) group AB negative RBC, O FFP, CMV-positive C) group O positive RBC, B FFP, CMV positive D) group O negative RBC, A,B FFP, CMV-negative |
D) group O negative RBC, A,B FFP, CMV-negative
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Which ABO group will react the weakest with anti-H lectin?
A) A1 B) B C) A2B D) A1B |
d) A1B
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Why is the Rh-positive first-born of an Rh-negative mother unaffected by Rh hemolytic disease of the newborn (HDN)?
A) The plasma volume of the mother is tripled during the first pregnancy which dilutes anti-D. B) The titer of anti-D is too low to cause destruction of fetal antigens. C) The mother has not been immunized to the D antigen before placental separation. D) none of the above |
C) The mother has not been immunized to the D antigen before placental separation.
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18.
A newborn hemoglobin level of 7 g/dL is indicative of severe anemia and corresponds to which zone of the Liley graph? A) zone I B) zone II C) zone III D) none of the above |
c) zone III
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A gene, such as the O gene, that produces no detectable product is called:
A) an amorph B) a trait C) an allele D) recessive |
a) an amorph
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Anti-A from a group B individual is primarily what class of immunoglobulin?
A) IgM B) IgG C) IgA D) all of the above |
a) IgM
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Rh immune globulin is effective is preventing which type of hemolytic disease of the newborn (HDN)?
A) anti-c B) anti-E C) anti-D D) anti-C |
c) anti D
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In order for the mother to be considered for RhIg, her Rh type must be and her newborn must be __________.
A) Du positive/Rh positive B) Rh negative/Rh positive C) Du negative/Du negative D) Rh positive/Rh negative |
b) Rh negative/Rh postive
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Reverse grouping showed negative reactions with A1 and B cells. Forward grouping showed positive reactions with A, B, and AB antisera. What blood type is consistent with these results?
A) A B) B C) AB D) O |
c) AB
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What is meant by the term "autosomal"?
A) Trait is not carried on the sex chromosomes. B) Trait is carried on sex chromosomes. C) Trait is not expressed in the parents. D) Organism possesses different alleles for a given characteristic. |
A) Trait is not carried on the sex chromosomes.
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What does the "R" represent in Rh-Hr terminology?
A) absence of D antigen B) presence of D antigen C) presence of C antigen D) presence of e antigen |
b presence of D antigen
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Which of the following best describes the principle of the Kleihauer-Betke test?
A) D-positive indicator cells form rosettes around maternal Rh-positive red cells. B) D-positive indicator cells form rosettes around fetal Rh-positive red cells. C) Maternal hemoglobin is resistant to acid (alkali) appearing pink, where fetal cells appear as ghost cells. D) Fetal hemoglobin is resistant to acid (alkali) and appear pink, where maternal red cells appear as ghost cells. |
D) Fetal hemoglobin is resistant to acid (alkali) and appear pink, where maternal red cells appear as ghost cells.
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Which of the following treatments use ultraviolet light to treat hyperbilirubinemia after the infant is delivered?
A) phototherapy B) plasma exchange C) amniocentesis D) electrophoresis |
a) phototherepy
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The most important serologic test for the diagnosis of hemolytic disease of the newborn (HDN) is the ________ with anti-IgG reagents.
A) elution B) IAT C) DAT D) fetal screen |
c) DAT
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What does the hh genotype refer to?
A) Lewis B) Sid C) Bombay D) Kell |
c) bombay
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What percentage of the type A population are A1?
A) 80% B) 50% C) 20% D) 10% |
a) 80%
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Which of the following best describes classical Genetics?
A) DNA alteration that is caused by a physical or chemical agent B) transmission of characteristics from parents to offspring C) possessing a pair of identical alleles D) the synthesis of RNA from DNA requiring RNA polymerase |
B) transmission of characteristics from parents to offspring
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A human gamete (egg or sperm) contains how many chromosomes?
A) 23 pairs B) 46 pairs C) 23 chromosomes D) 46 chromosomes |
c) 23 chromosomes
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A woman with blood group A marries a man with blood group O. Their first born child has blood group O. The mother's most probable genotype is:
A) OO B) AA C) AB D) AO |
d) AO
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Persons who inherit the h allele do not produce ___________ transferase necessary for formation of the H structure.
A) L-fucosyl B) N-acetylgalactosaminyl C) D-galactosyl D) D-glucosyl |
A) L-fucosyl
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What immunodominant sugar is responsible for A specificity?
A) N-acetyl-D-galactosamine B) D-galactose C) L-fucose D) D-glucose |
a) N-acetyl-D-galactosamine
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Which of the following assays is used to detect presence of fetomaternal hemorrhage in a postpartum specimen?
A) antibody screen B) Kleihauer-Betke C) rosette test D) DAT |
c) rosette test
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In a pedigree analysis, what do vertical lines indicate?
A) consanguineous mating B) offspring C) stillbirth D) deceased sibling |
b) offspring
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