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3 Cards in this Set
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- Back
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1. Describe the structural differences observed for the corticosteroids compared to progesterone.
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Both cortisol and aldosterone are different from progesterone:
11b-OH C-21 OH |
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how is cortisol diff from aldosterone?
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Cortisol: 17a-OH
Aldosterone: C-18 aldehyde rather than typical methyl |
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2. Describe the role of CYP450 enzymes in steroid hormone synthesis.
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Many P450's involved in synthesis, but are SUBSTRATE SPECIFIC unlike the drug-metabolizing CYP450s
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