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9 Cards in this Set
- Front
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Epinephrine (Adrenalin)
Class |
Sympathomimetic, Catecholamine, Vasopressor
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Epinephrine (Adrenalin)
MOA |
1. Increases cardiac output due to increased inotropy, chronotropy, and AV conduction (beta1 effect)
2. Increases systolic blood pressure (alpha and beta1 effect) 3. Relaxes the smooth muscles in the respiratory tract (beta2 effect) 4. Increases coronary perfusion during CPR by increasing aortic diastolic pressure 5. Dilates the bronchioles (beta2 effect) |
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Epinephrine (Adrenalin)
Indications |
1. Cardiac Arrest
2. Asthma 3. Allergic reaction and Anaphylactic shock |
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Epinephrine (Adrenalin)
Contraindications |
1. Hypovolemia
2. HTN |
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Epinephrine (Adrenalin)
Side Effects |
Cardiovascular: tachycardia, hypertension, palpitations, chest pain, ventricular fibrillation
Neurological: tremors/seizures Respiratory: paradoxical bronchospasms (with excessive use in inhalers) |
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Epinephrine (Adrenalin)
Precautions |
1. Give slow IVP in conscious patients as it may cause permanent hearing loss
2. Monitor blood pressure and ECG frequently after administration due to the high incidence of cardiovascular side effects in patients above the age of 40 |
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Epinephrine (Adrenalin)
Interactions |
Flush tubing before and after administration of Sodium Bicarbonate, as Epinephrine will be inactivated by the change in pH
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Epinephrine (Adrenalin)
Adult Routes / Dosages |
IVP, IO, SQ, ET (can consider IM administration)
Cardiac Arrest: 1 mg (1:10,000) IVP/IO or 2 mg (1:1,000) ET May repeat every 3-5 minutes Asthma/Allergic Reaction: 0.3 mg- 0.5 mg (1:1,000) SQ (if patient is perfusing) May repeat every 20 minutes x 2 Anaphylaxis with Shock: 0.1 mg (1:10,000) slow IVP/IO (over 1 minute) May repeat every 3-5 minutes |
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Epinephrine (Adrenalin)
Pediatrics Routes / Dosages |
Cardiac Arrest: 0.01 mg/kg (1:10,000) IVP/IO or 0.1 mg/kg (1:1,000) ET
May repeat 0.01 mg/kg IVP/IO/ET every 3-5 minutes Subsequent doses may switch to a 1:1,000 concentration Asthma/Allergic Reaction: 0.01 mg/kg (1:1,000) SQ to a maximum single dose of 0.3 mg (if patient is perfusing) May repeat every 20 minutes x 2 Anaphylaxis with Shock: 0.01 mg/kg (1:10,000) slow IVP/IO (over 1 minute) to a maximum single dose of 0.1 mg May repeat every 3-5 minutes Bradydysrhythmia (<80 HR for neonate/infant or <60 HR for child): Neonate/Infant 0.01 mg/kg (1:10,000) IVP/IO or 0.1 mg/kg (1:1,000) ET May repeat 0.1 mg/kg IVP/IO/ET every 3-5 minutes Child 0.01 mg/kg (1:10,000) IVP/IO or 0.1 mg/kg (1:1,000) ET If no response, consider Atropine |