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8 Cards in this Set

  • Front
  • Back

Cells may communicate with one another by ____

Transferring signal molecules to adjacent cells through gap junctions; Local-acting chemicals, called paracrines and autocrines; Long-distance means, which rely on combinations of electrical and chemical signals

Describe the characteristics of autocrine and paracrine control

Autocrine and paracrine control use chemicals (ligands) to regulate cell activity; Paracrine control is when a cell regulates its neighbor; Target cells have receptors that recognize and bind the specific chemical (paracrine, autocrine or hormone)

Peptide hormones regulate their target cells by

binding to cell surface receptors which activate intracellular signaling pathways

Describe the mechanism used by the tyrosine derivative hormones, epinephrine and thyroid hormone, to trigger their target cell's response

Thyroid hormone (TH) binds intracellular receptors to increase gene expression

When steroid hormones bind to their receptors

gene transcription is activated

Joanne presents to her physician with elevated plasma cortisol levels. She is administered dexamethasone, a drug used to suppress the secretion of ACTH from the pituitary gland. her plasma cortisol levels fall to normal 60 minutes after the dexamethasone treatment. Joanne's condition can be described as

Second pathology because suppression of the pituitary hormone, ACTH, corrected the secretion of cortisol from the adrenal gland

Describe steroid hormones

They require carrier proteins for delivery to target tissues

The single most important factor that determines whether a specific gene in a given cell can be regulated by growth hormone is the presence in this cell of

specific growth hormone receptors