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30 Cards in this Set
- Front
- Back
Treatment of pheochromocytoma?
class? |
phenoxybenzamine
alpha blocker |
|
Treatment of SIADH?
|
demeclocycline
|
|
Blockers of 5'-deiodinase (3)
|
propranolol
glucocorticoids propylthiouracil |
|
What is a goitrogen?
|
a chemical that causes goiter (i.e. a hypertrophied thyroid gland)
|
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Goitrogens:
inhibitors of iodine transport (2) inhibitors of binding/coupling (2) |
thiocyanate
perchlorate propylthiouracil methimazole |
|
Calcitonin can be used therapeutically for.... (2)
|
osteoporosis
Paget's and anything else involved with hypercalcemia |
|
Important treatment for hyperkalemia
|
Give insulin
|
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Treatment for Conn's syndrome
|
spironolactone
|
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Treatment of diabetes insipidus:
central (1) nephrogenic (3) |
desmopressin
hydrochlorothiazide indomethacin amiloride |
|
Treatment of carcinoid syndrome
whate else is this agent used to treat (2) |
octreotide
intractable diarrhea GI bleeding |
|
Another name for GnRH
|
gonadorelin
|
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Leuprolide indications:
pulsatile use (1) continuous use (3) |
infertility
(acts as a GnRH agonist) prostrate cancer uterine fibroids endometriosus (acts as a GnRH antagonist) |
|
Bromocriptine MOA?
use? (2) |
dopamine receptor agonist
hyperprolactinemia acromegaly |
|
Oxcytocin use? (2)
|
induce labor
decrease postpartum bleeding dinoprostone is also used for the former |
|
name two uterine relaxants and their MOA
|
ritodrine
terbutaline B2 agonists |
|
What are menotropins and what are they used for?
|
partially degraded FSH and LH
used to induce follicle maturation in infertile women |
|
ACTH analog?
|
cosyntropin
|
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Name three agents used to treat hypothyroidism
|
levothyroxine (T4)
Liothyronine Liotrix (combo of the above two) |
|
Iodine use? (2)
|
pre-ope shrink of thyroid
thyroid storm |
|
Propylthiouracil and methimazile MOA?
use? which one can inhibit peripheral conversion of T4 to T3? |
inhibit peroxidase enzymes
hyperthyroidism propylthiouracil |
|
most serious SE of propylthiouracil?
why is it preferred in pregnancy and why? |
agranulocytosis
PTU is more protien bond and has less chance to cross placenta or milk to induce hypothyroidim |
|
Treatment for severe tetany as well as severe hyperkalemia
|
calcium gluconate
|
|
Disphosphonates:
Name two? MOA? use? |
etidronate disodium
pamidronate disodium bind hydroxyapatie crystals and stalls bone resorption Pagets osteoporosis and others |
|
Treatment for bronchial asthma
|
beclmethasone
|
|
ketoconazole MOA?
use? (2) |
inhibits steroid synthesis
polycystic ovarian syndrome hirsutism |
|
Name 4 sulfonylureas?
MOA? use? |
tolbutamide chlopropamide
glyburide glypizide stimulate B cells to secrete insulin NIDDM |
|
SE of 1st generation sulfonylureas (tolbutamide, chlorpropamide)
|
disulfiram like effects
|
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Metformin use?
SE? |
anti-hyperglycemic
(unknowm mechanism) lactic acidosis |
|
acarbose and miglitol MOA?
|
a-glucosidase inhibitors in brush border decreases glucose absorption
|
|
Glitazones: (pioglitazone, rosiglitazone, troglitazone)
MOA? |
increase the sensitivity of tissues to insulin by binding PPARS
|