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6 Cards in this Set
- Front
- Back
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Pancreas produces what from where?
What regulates flow of bile/pancreatic secretions and prevents reflux? Exocrine pancreas: |
Exocrine - digestive enzymes
hormones - Islets of Langerhans Sphincter of Oddi digestion enzymes, simple epithelial serous cells (small, dark staining); compound tubuloacinar (branched, flask shaped) |
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What do duct cells add to secretions?
Order of ducts from secreting cells: Epithelium type in intralobular duct? How to recognize interlobular duct? |
HCO3- and H2O - neutralizes acidity
intercalated --> intralobular --> interlobular cuboidal runs with pancreatic artery, vein |
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How are enzymes stored in acinar cells?
What stimulates release/exocytosis? Enzymes released? |
zymogen granules
PNS via vagus n., CCK proteases, lipases, amylases, RNases, DNases, HCO3- |
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Difference between acinar and centroacinar cells?
Where are Islets of Langerhans more abundant? Appearance? Explain the insuloacinar portal system: |
centroacinar nucleus surrounded by pale cytoplasm, no zymogen granules - produce HCO3, watery fluid, secretin
lighter staining collection of cells in tail of pancreas afferent arteriole --> fenestrated capillaries --> efferent arteriole --> acini |
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4 major cell types and secretions?
What are G cells? EC cells? |
A - glucagon - triggered by low BS
B - insulin - high BS D - somatostatin - paracrine, inhibits release of other pancreatic hormones; VIP - similar to glucagon F (PP - pancreatic polypeptide) - PP's - inhibits secretion of digestive enzymes, HCO3-, HCl from parietal cells G - produces gastrin; EC cells - secretin, motilin, substance P |
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PNS stimuilation causes what in the endocrine pancreas? SNS?
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PNS - increased insulin, glucagon
SNS - inhibits insulin release |
