Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
14 Cards in this Set
- Front
- Back
|
Which type of prostanoids are used for induction of abortion, labor and to treat post part uterine bleeding? |
PGE2 and their analogues PGF-2a and their analogues |
|
|
Name PGE2 drug(s) |
Dinoprostone |
|
|
Name the PGE2 analogues |
Sulprostone |
|
|
Name PGF-2a drug(s) |
Dinoprost (Dinoprostone is PGE2!) |
|
|
Name PGF-2a analogues for abortion and uterine bleedings from delivery |
Carboprost and tromethamine |
|
|
Name PGF-2a analogues that can treat glaucoma, but can cause discolouration of the iris (latino priest, travbaneprest, uno prost...) |
Latanoprost, Unoprostone, Bimatoprost, Travoprost |
|
|
Name a PGE1 drugs and receptors |
Alprostadil, Misoprostol, Gemeprost, Lubiprostone |
|
|
Name PGI2 analogues |
Epoprostenol, iloprost and Tresponil. |
|
|
What are the PGI2 drugs used for? |
Used to treat primary or secondary pulmonary hypertension. And to to inhibit platelet aggregation. |
|
|
What does Mifepristone do? |
Competitive progesterone receptor antagonist. Used to interrupt early pregnancies (under 7 weeks) |
|
|
Which drug is used in combination with mifepristone? |
Misoprostol or gemeprost |
|
|
What is the effect of Misoprostol in GIT? |
Protects gastric mucosa from NSAIDs |
|
|
Effect of Lubiprostone? |
Opens Cl- channels in intestines -> laxative |
|
|
Effects of Alprostadil? |
Maintains patent ductus arterioles. Used to treat erectile dysfunction Inhibits platelet aggregation |
