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3 Cards in this Set
- Front
- Back
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In clinical trails, what is the usefulness of a surrogate endpoint?
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It is a clinical substitute for a 'true' endpoint which can be easily measured and is often significant to the patient's wellbeing. It also makes the study faster.
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Name four advantages of RCTs.
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- Randomisation of subjects
- Distribution of confounding variables - Double blinding - Best evidence for a cause-effect relationship |
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Name four disadvantages of RCTs.
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- Very costly
- Difficult to design - Follow-up losses common - Limited generalisability |
