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18 Cards in this Set
- Front
- Back
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What are ecoli?
What are shigella sp? |
gram neg rod,gram neg rod
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what does macconkey agar do to all gram negs?
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Inhibits their growth
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Lactose +
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E coli,
enterobacter, klebsiella, proteus |
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lac -
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shigella, salmonella
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What are endogenous infections?
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Normal flora getting into a new place
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exogenous?
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unique strains of bacteria causing disease
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What gives you travelers diarrhea?
What is heat labile toxin like? how does it work? |
ETEC
very much like cholera toxin activates adenylate cyclase |
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What is Heat stable toxin?
similarity between ls and hs? |
stimulates guanylate cyclase
both produce secretory diarrhea |
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EHEC uses what toxin?
What does this toxin do? |
Shiga like toxin
inhibits protein synthesis, causes HUS, and dysentery, destruction of renal cells |
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Can ecoli ever be b hemolytic
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yes
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EHEC? animal to human or human to human?
REstaurant? serotype famous? Other thing it could be called? |
animal to human
Jack in the Box O157: H7 STEC |
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What's special about the german outbreak?
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two copies of shiga like toxin
sorbitol positive Higher HUS rates acquired fimbriae genes from enteroaggregative ecoli |
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Incubation period of EHEC?
how does it begin? how long before bloody? fever, invasion, pus? |
2-5 days
watery diarrhea 1-2 days yes, there are sometimes but less than other more invasive bacteria. |
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What's a big complication of EHEC?
What happens on a sorbitol macconckey agar with EHEC? |
HUS
The EHEC colonies will be less colorful (pretty much clear) |
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Do you give antibiotics with EHEC HUS?
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NO
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Shigella
Normal flora? h antigen? k antigen? Virulence factors? transmission |
Not normal flora
NO no, Invasion plasmid and shigella toxin (exotoxin) fecal/oral |
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Shigellosis
fever? invades which cells inititially? usually bloody? |
yes fever
M cells No |
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S. Dysenteriae
what makes this worse? are there ulcerations? How distinguish between ehec |
Lots more toxin produced
Yes Ulcerations |
