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74 Cards in this Set
- Front
- Back
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What is the antidote for acetaminophen toxicity/overdose
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N-acetylcysteine
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What is the antidote for salicylates toxicity/overdose
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Alkanize urine/dialysis
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What is the antidote for antichoinesterase toxicity/overdose
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Atropine, pralidoxime
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What is the antidote for antimuscarinic/anticholinergic agents toxicity/overdose
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physostigimine salicylate
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What is the antidote for Beta-blockers toxicity/overdose
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glucagon
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What is the antidote fordigitalis toxicity/overdose
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Stop digitalis, Normalize K+, lodpcaine, anti-digitialis Fab Fragments, Magnesium
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What is the antidote for lead toxicity/overdose
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CaEDTA, dimercaprol, succimer, penicillamine
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What is the antidote for iron toxicity/overdose
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Deferoxamine
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What is the antidote for aresnic/mercury/gold toxicity/overdose
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Dimercaprol (BAL), succimer
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What is the antidote for copper, arsenic, gold toxicity/overdose
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Penicillamine
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What is the antidote N-acetylcysteine used to treat?
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Acetaminophen toxicity/overdose
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What is the antidote for cyanide toxicity/overdose
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nitrite, hydroxocobalamin, thiosoulfate
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What is the antidote for methemoglobin toxicity/overdose
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methylene blue
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What is the antidote glucagon used to treat?
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Beta-blocker toxicity/overdose
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What is the antidote for carbon monoxide toxicity/overdose
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100% oxygen, hyperbaric oxygen
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What is the antidote atropine used to treat?
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anticholinesterase toxicity/overdose
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What is the antidote for methanol toxicity/overdose
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Ethanol, dialusis, fomepizole
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What is the antidote for opiods toxicity/overdose
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Nalozone/naltrexone
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What is the antidote for ethylene glycol toxicity/overdose
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Ethanol, dialusis, fomepizole
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What is the antidote for benzodiazepines toxicity/overdose
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Flumazenil
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What is the antidote for (TCA) Tricyclic Antidepressants toxicity/overdose
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NaHCO3
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What is the antidote for Heparin toxicity/overdose
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Protamine
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What is the antidote Deferoxamine used to treat?
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Iron toxicity/overdose
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What is the antidote for warfarin toxicity/overdose
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vitamin K, fresh frozen plasma
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What is the antidote Naloxone/naltrexone used to treat?
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opioid toxicity/overdose
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What is the antidote for tPA/streptokinase toxicity/overdose
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aminocaproic acid
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What is the antidote Physostigmine salicylate used to treat?
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Antimuscarinic/anticholinergic agents toxicity/overdose
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What is the antidote Flumazenil used to treat?
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Benzodiazepine toxicity/overdose
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What is the antidote Protamine used to treat
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Heparin toxicity/overdose
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Children living in old houses might eat the paint chips which could cause ____
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Lead Poisoning
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Signs of Lead poisoning include:
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Lead Lines on gingivae and epiphyses of Long bones, Encephalopathy and Erythrocyte Basophilic stippling, Abdominal colic and sideroblastic Anemia, Wrist and Foot Drop
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1st line of Treatment for Lead Poisoning include
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Dimercaprol and EDTA
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Weak acids, such as phenobarbitol, methotreaxate, aspirin, alkanize urine with ____ to increase clearance
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bicarbonate
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Weak bases, such as amphetamines, acidify urine with NH4Cl to ____ clearance
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increase
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Pulmonary fibrosis (3)
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bleomycin, amiodarone, busulfan
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Hepatitis (2)
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isoniazid, halothane
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Focal to massive hepatic necrosis (4)
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halothane, valproic acid, acetaminophen, amanita phalloides
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Anaphylaxis (1)
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penicillin
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SLE-like syndrome (4). [mnemonic: it's not HIPP to have lupus]
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hydralazine, INH, procainamide, phenytoin
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Hemolysis in G6PD-deficient patients (8)
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sulfonamides, INH, aspirin, ibuprofen, primaquine, nitrofurantoin, pyrimethamine, chloramphenicol
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Thrombotic complications (1 class)
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OCPs (e.g. estrogens and progestins)
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Adrenocortical insufficiency (withdrawal of what class of drugs causes adrenocortical insufficiency?)
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withdrawal of glucocorticoids causes hypothalamic-pituitary-axis suppression
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Photosensitivity reactions (3) [mnemonic: SAT for a photo]
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Sulfonamides, amiodarone, tetracycline
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Induce P-450 system (6)
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barbiturates, phenytoin, carbamazepine, rifampin, griseofulvin, quinidine
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Inhibit P-450 system (6, including one fruit)
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cimetidine, ketoconazole, grapefruit, erythromycin, INH, sulfonamides
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Tubulointerstitial nephritis (5)
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sulfonamides, furosemide, methicillin, rifampin, NSAIDs (except aspirin)
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Hot flashes (1)
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Tamoxifen
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Cutaneous flushing (4)
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niacin, Ca++ channel blockers, adenosine, vancomycin
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Cardiac toxicity (2)
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doxorubicin (adriamycin), daunorubicin
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Agranulocytosis (3, all start with letter C)
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clozapine, carbamazepine, colchicine
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Stevens-Johnson syndrome (3)
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ethosuximide, sulfonamides, lamotrigine
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Cinchonism (2)
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quinidine, quinine
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Tendonitis, tendon rupture and cartilage damage (kids) (1)
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fluoroquinolones
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Disulfiram-like reaction (4)
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metronidazole, certain cephalosporins, procarbazine, sulfonylureas
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Otoxicity and nephrotoxicity (3)
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aminoglycosides, loop diuretics, cisplatin
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Drug-induced Parkinson's (4)
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haloperidol, chlorpromazine, resperine, MPTP
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Torsades de pointes (two subclasses of antiarrhythmics)
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Class III (sotalol), class IA (quinidine) antiarrhythmics
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Aplastic anemia (3)
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chloramphenicol, benzene, NSAIDs
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Neuro/nephrotoxicity (1)
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polymyxins
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Pseudomembranous colitis (2)
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clindamycin, ampicillin
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Gynecomastia (5) [mnemonic: Some Drugs Create Awesome Knockers]
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spironolactone, digitalis, cimetidine, chronic Alcohol use, estrogens, ketoconazole
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Atropine-like side effects (1)
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tricyclics
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Cough (1)
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ACE inhibitors (losartan --> no cough)
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Gingival hyperplasia (1)
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phenytoin
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Diabetes insipidus (1)
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lithium
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Tardive dyskinesia (1)
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antipsychotics
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Fanconi's syndrome (1)
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tetracycline
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Gray baby syndrome (1)
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chloramphenicol
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Extrapyramidal side effects (3)
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chlorpromazine, thioridazine, haloperidol
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Osteoporosis (2)
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corticosteroids, heparin
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What drug causes coronary vasospasm?
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cocaine
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What drugs cause actue cholestatic hepatitis? (1)
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Macrolides
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What drugs cause hemorrhagic cystitis? (2)
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Cyclophosphamide, ifosfamide
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What drugs cause seizures? (3)
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Buproprion, imipenem/cilastatin
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