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3 Cards in this Set
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- Back
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Directly acting spasmolytics ( non receptorial mode of action so via enzymes or ion channels ) |
Papaverine Drotaverine Bencyclane Metamizol |
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Papaverine ( naturally occurring in poppy seed ) |
Inhibiton of voltage gates L-type calcium channel Inhibiton Of phosphodiesterase 3 and 4. ( elevating cAMP level causing relaxation ) |
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Drotaverine |
Semisynthetic derivative of papaverine Selectively inhibits PDE 4 —> minimal Cardiac side effects |
