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21 Cards in this Set
- Front
- Back
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Name all the drugs that act as a PDE inhibitors.
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Papaverine
Sildenafil Theophylline Caffeine |
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Name all the drugs that affect ACH release/synthesis
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botulinum toxin
hemicholinium tetanus toxin alpha-latrotoxin |
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Name all the drugs that are cholinergic agonists
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acetylcholine
methacholine carbachol bethanechol succinylcholine pilocarpine cevimeline |
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Name the drugs that are used to treat glaucoma.
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pilocarpine
betaxolol timolol latanoprost epinephrine dipivefrin apraclonidine acetazolamide dorzolamide isofluophate echothiophate mannitol |
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Name the Carbamate ACHase inhibitors.
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Physostigmine
Donepezil neostigmine pyridostigmine edrophonium carbaryl |
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Name the OP ACHase inhibitors
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Dimpylate
Isofluophate Parathion Malathion Echothiophate |
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Name the drug use to the treat OP poisoning.
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Pralidoxime
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Name the tertiary muscarinic antagonists.
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Atropine
Scopolamine Cyclopentolate Tropicamide Benztropine Trihexyphenidyl Dicyclomine Hyoscyamine oxybutynin tolterodine solifenacin darifenacin diphenhydramine |
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Name the quaternary muscarinic antagonist.
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N-methylatropine
methscopolamine ipratropium glycopyrrolate propantheline trospium |
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Name the nicotinic receptor agonist.
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nicotine
succinylcholine |
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Name the adrenergic agonists
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NE
Epi DA Dobutamine Isoproterenol Salmeterol Terbutaline Albuterol Pirbuterol Ritodrine Phenylephrine Oxymetazoline Tyramine Amphetamine Phenylpropanolamine Ephedrine Pseudoephedrine |
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Name the ganglionic blocking drugs
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Trimethaphan
Mecamylamine |
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Name the alpha antagonists.
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Phenoxybenzamine
phentolamine prazosin tamsulosin labetalol yohimbine ergotamine, dihydroergotamine |
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Name the drugs used to treat impotence
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Phentolamine
Papaverine Alprostadil SIldenafil |
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Name the drugs used as B antagonists
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Betaxolol
atenolol metoprolol esmolol propanolol timolol labetalol |
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Name the drugs used as sympatholytic drugs
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Alpha methyldopa
Reserpine Guanethidine |
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Name the drugs that alter NE metabolism
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Cocaine
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Botulinum Toxin
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MOA
- Binds to surface protein and transported into cholinergic neurons -protease activity hydrolyzes the proteins involved in the synaptic storage and exocytotic release of ACH - Neurotransmission ceases in the nerve that supply NMJ Therefore: muscle paralysis Therapeutic use: -Laryngeal dystonia -strabismus -hemifacial spasm |
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Tetanus Toxin
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MOA:
Prevent the release of inhibitory NT at the spinal cord. Causes: Spastic paralysis |
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Hemicholinium
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Prevents Ach synthesis by blocking choline uptake.
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Drugs affecting degradation of ACH
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1. Slowly-reversible carbamate inhibitors of Achase
2. Irreversible OP inhibitors of AcHAse |
