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155 Cards in this Set

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Cimetidine
H2 Receptor Antagonist
Ranitidine
H2 Receptor Antagonist
Omeprazole
Proton Pump Inhibitor
Pirenzepine
Muscarinic M1 Antagonist



(The Original Anti-Ulcer Drug)


(Not used anymore due to side effects)

Aluminium Hydroxide
Antacid
Magnesium Hydroxide
Antacid
Sodium Bicarbonate
Antacid
Sucralfate
Mucosal Protectant
Colloidal Bismuth
Mucosal Protectant
Misoprostol

Synthetic Prostaglandin E1



Mucosal Protectant
Indomethacin
Cyclooxygenase Inhibitor
Ibuprophen
Cyclooxygenase Inhibitor
Colchicine
Microtubule Assembly Inhibitor
Allopurinol
Competitive Xanthine Oxidase Inhibitor
Probenecid
Uricosuric Agent
Sulphinpyrazone
Uricosuric Agent
Uricase
Uric Acid Metabolizer
Hydroxychloroquine
Disease Modifying Antirheumatic Drug (DMARD)
Sulphasalazine
Disease Modifying Antirheumatic Drug (DMARD)
Sodium Aurothiomalate
Gold Salt



Macrophage Suppression

Aurofin
Gold Salt



Macrophage Suppression

Penicillamine
Chelates Heavy Metals
Methotraxate
Folic Acid Antagonist
Leflunomide
Dihydroorotate Dehydrogenase Inhibitor
Azathioprine
Purine Analogue Cytotoxic to Inflammatory Cells
Cyclosporine
Antibiotic
Salbutamol
Beta 2 Agonist
Adrenaline
Non-Selective Adrenergic Agonist
Isoprenaline
Non-Selective Adrenergic Agonist
Theophylline
Phosphodiesterase Inhibitor



Xanthine Class

Ipratropium
Non-Selective Muscarinic Receptor Antagonist
Cromoglycate
Prophylactic Agent for Asthmatics
Beclomethasone
Glucocorticoid
Zileuton
5-Lipoxygenase Inhibitor
Zafirlukast
cysLT1 Receptor Antagonist
Montelukast
cysLT1 Receptor Antagonist
Nifedipine (Inhaled)
Calcium Channel Blocker
Verapamil (Inhaled)
Calcium Channel Blocker
Chromakalim
Potassium Channel Openers
Omalizumab
Anti-IgE Monoclonal Antibodies
Tropicamide
Muscarinic Antagonist
Timolol
Beta Receptor Antagonist
Dorzolamide
Carbonic Anhydrase Inhibitor
Pilocarpine
Muscarinic Agonist
Lanaprost
Prostaglandin F2 alpha Analogue
Verteprofin
Photodynamic Therapy Agent
Ranibizumab
VEGF Monoclonal Antibodies
Metronidazole
Prodrug of Cytotoxic, Antibiotic Compound



Clinically Used to Kill Amoeba and Anaerobic Organisms

Pentamidine
DHFR Inhibitor



Clinicallyused to treat Early Stage (non-CNS) in Trypanosomiasis (Sleeping Sickness)

Suramin
Multi-Enzyme Inhibitor



Clinicallyused to treat Early Stage (non-CNS) in Trypanosomiasis (Sleeping Sickness)

Melarsopol
Combination of Dimercaptopropanol and Melarsen Oxide (Arsenic Compound)



Clinicallyused to treat Late Stage (CNS) in Trypanosomiasis (Sleeping Sickness)

Sodium Stibogluconate
Anti-Protazoal Agent
Meglumine Antimonate
Anit-Protazoal Agent
Miltefosine
Anti-Protazoal Agent



Synthetic Ether Phospholipid Analogue

Ivermectin
Semisynthetic Macrocyclic Lactone



Clinically used against many Helminths and Arthropods

Piperazine
GABA Receptor Agonist



Clinically used (historically) to treat Round Worm and Pin Worm

Pyrantel Pamoate
Cation Channel Agonist



Depolarizing Neuromuscular Blocking Agent




Clinically Used as Third Line Agent against Hookworm, Pinworm, or Roundworm Infections

Albendazole
Microtubule Assembly Inhibitor



Anti-Helminthic Agent

Mebendazole
Microtuble Assembly Inhibitor



Anti-Helminthic Agent

Praziquantel
Anti-Helminthic Agent
Diethylcarbamizine (DEC)
Piperazine Derivative



Anti-Helminthic Agent

Erlotinib
EGFR Inhibitor



Anti-Cancer Agent

Cetuximab
Chimeric Mouse/Human IgG1 Monoclonal Antibody to EGFR (ErbB1)



Anti-Cancer Agent

Trastuzumab
Chimeric Mouse/Human IgG1 Monoclonal Antibody to EGFR (ErbB2)



Anti-Cancer Agent

Imatinib Mesylate
Tyrosine Kinase Inhibitor



Anti-Cancer Agent

Tipifarnib
Farnesyltransferase Inhibitor



Clinically used for Relapsed/Refractory AML

Sorafenib
Multiple rTK Inhibitor (VEGFR-1, VEGFR-2, PDGFR, and B-RAF Kinase)



Anti-Cancer Agent

Bortezomib
Proteasome Inhibitor



Anti-Cancer Agent

Bevacizumab
Humanised Mouse IgG1 Antibody against VEGF-A



Anti-Cancer Agent

Vatalanib
VEGFR-1 and VEGFR-2 Inhibitor
Rituximab
Anti-CD20 Antibody



Targets B Cell Non-Hodgkin's Lymphoma

Alemtuzumab
Anti-CD52 Antibody



Targets Chronic Lymphocytic Leukaemia

Gemtuzumab
Anti-CD33 Antibody Conjugated to Calicheamicin



Targets Acute Myeloid Leukaemia

Enfuvirtide
Anti-HIV Peptide



Fusion Inhibitor




Anti-HIV Drrug

Amantadine
Ion Channel Inhibitor



Anti-Influenza A Drug

Rimantadine
Ion Channel Inhibitor



Anti-Influenza A Drug

Raltegravir
HIV Integrase Inhibitor



Anti-HIV Drug

Zidovudine (AZT)
Thymidine Analogue



Nucleoside Reverse Transcriptase Inhibitor (NRTI)




Anti-HIV Drug

Lamivudine (3TC)
Cytidine Analogue



Nucleoside Reverse Transciptase Inhibitor (NRTI)




Anti-HIV Drug

Acyclovir
Guanine Base Attached to Incomplete Sugar



Anti-HSV/VCZ Drug

Efavirenz
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)



Anti-HIV Drug

Nevirapine
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)



Anti-HIV Drug

Ritonavir
HIV Protease Inhibitor



Anti-HIV Drug

Saquinavir
HIV Protease Inhibitor



Anti-HIV Drug

Zanamivir
Sialic Acid Analogue



Anti-Influenza Drug

Oseltamivir
Prodrug Sialic Acid Analogue



Anti-Influenza Drug

Ketoconazole

CYP450 Enzyme Inhibitor (specifically ones involved with production of Cortisol and Aldosterone)



Anti-Fungal Drug
Metyrapone
Reversible 11 beta - Hyroxylase Inhibitor
Hydrocortisone (Cortisol)
Endogenous Glucocorticoid
Cortisone
Pro-Drug Version of Glucocorticoid
Prednisone
Pro-Drug Version of Glucocorticoid
Prednisolone
Synthetic Glucocorticoid
Dexamethasone
Synthetic Glucocorticoid
Fluticasone
Synthetic Glucocorticoid
Beclomethasone
Synthetic Glucocorticoid
Methylprednisolone
Synthetic Cortisol Analogue
Fludrocortisone
Synthetic Cortisol Analogue with High Mineralocorticoid Activity
Spironolactone
Competative Aldosterone Receptor Antagonist



Potassium Sparing Diuretic

Eplerenone
Competitve Aldosterone Receptor Antagonist



Potassium Sparing Diuretic

Simvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Lovastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Pravastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Atorvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Long Acting Statin

Rosuvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Long Acting Statin

Gemfibrozil
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lowering Agent

Fenofibrate
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lowering Agent

Ciprofibrate
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lower Agent

Colestyramine
Bile Acid-Binding Resin



Lipid Lowering Agent

Colestipol
Bile Acid-Binding Resin



Lipid Lowering Agent

Ezetimibe
Niemann-Pick C1-like 1 (NCPC1L1) Cholesterol Transport Protein Inhibitor



Cholesterol Absorption Inhibitor

Niacin
Nicotinic Acid (Vitamin B3)



Lipid Lowering Agent

Omacor
Polyunsaturated Fatty Acids



(Ex. Eicosapentaenoic and Docosahexaenoic Acid)




Fish Oil Derivative




Lipid Lowering Agent

Aspirin
Irreversible Cyclooxygenase Inhibitor



First Line Anti-Platelet Agent

Clopidogrel
Irreversible ADP Receptor Inhibitor



Second Line Anti-Platelet Agent (or combo with Aspirin)

Prasugrel
Irreversible ADP Receptor Inhibitor



Anti-Platelet Agent

Dipyridamole
Phosphodiesterase Inhibitor



Anti-Platelet Agent (relatively weak)

Abciximab
Irreversible GPIIb-IIIa Antagonist (monoclonal antibody)



Anti-Platelet Agent

Eptifibatide
GPIIb-IIIa Antagonist
Tirofiban
GPIIb-IIIa Antagonist
Heparin (unfractionated)
Thrombin and Factor Xa Inhibitor



Anti-Coagulant

Dalteparin
Factor Xa Inhibitor



Anti-Coagulant




Heparin (low molecular weight)

Enoxaparin
Factor Xa Inhibitor



Anti-Coagulant




Heparin (low molecular weight)

Lepirudin
Direct Thrombin Inhibitor
Warfarin
Competitive Vitamin K Epoxide Reductase Component 1 (VKORC1) Inhibitor



Anti-Coagulant

Dabigatran
Direct Thrombin Inhibitor
Rivaroxaban
Factor Xa Inhibitor
Protamine Sulphate
Heparin Antidote
Streptokinase
Plasminogen Activator



Fibrinolysis/Thrombolytic Agent

Alteplase
Recombinant Tissue Plasminogen Activator (t-PA)



Fibrinolysis/Thrombolytic Agent

Tranexamic Acid
Lysine Analogue



Plasminogen Activation Inhibitor




Anti-Fibrinolytic Drugs

Aminocaproic Acid
Lysine Analogue



Plasminogen Activation Inhibitor




Anti-Fibrinolytic Drugs

Desmopressin
Synthetic ADH Analogue



Anti-Fibrinolytic Drugs

Etamyslate
Synthetic Haemostasis Drug



Indicated for short-term blood loss in menorrhagia

Eptacog Alfa
Recombinant Factor VIIa

Celecoxib

Selective COX-2 Inhibitor

Diclofenac

COX Inhibitor




(More selective for COX-2)

Piroxicam

COX Inhibitor




(More selective for COX-1)




Indicated for RA and OA (but not as a first-line agent)

Infliximab

Monoclonal Antibody against TNF-α




Indicated for RA, Psoriasis, Crohn's Disease and other Autoimmune Diseases

Adalimumab

Monoclonal Antibody against TNF-α




Indicated for RA, Psoriasis, Crohn’s Disease& other Autoimmune Diseases

Etanercept

Monoclonal Antibody against TNF-α




Indicated for RA, Psoriasis, Crohn’s Disease & other Autoimmune Diseases

Anakinra

IL-1 Receptor Antagonist




Indicated for RA, Psoriasis, Crohn’s Disease & other Autoimmune Diseases

Epoprostenol

PGI 2 Analogue




Clinically used to prevent platelet aggregation and primary pulmonary hypertension

Cicaprost

PGI 2 Anaglogue




Clinically used to prevent platelet aggregation and primary pulmonary hypertension

Iloprost

PGI 2 Analogue




Clinically used to prevent platelet aggregation and primary pulmonary hypertension

Latanoprost

PGF 2 Alpha Analogue




Clinically Used to treat Open Angle Glaucoma and Ocular Hypertension

Travoprost

PGF 2 Alpha Analogue




Clinically Used to treat Open Angle Glaucoma and Ocular Hypertension

What is the Antidote for Paracetamol Overdose?

Acetylcystein IV




(precursor to Glutathione which is depleted due to OD)



What is the Antidote for Iron Poisoning?

Desferrioxamine




(Chelating Agent)

What is the Antidote for Benzodiazepine Overdose?

Flumazenil




(Competitive Antagonist)

What is the Antidote for Opiod Overdose?

Naloxone




(Competitive Antagonist)

What is the Antidote for Digoxin Overdose?

Digoxin-Specific Antibody Fragments (fab)

What is the Antidote for Insulin Overdose?

Dextrose and/or Glucagon

What is the Antidote for Warfarin Overdose?

Vitamin K

What is the Antidote for Aspirin (Salicylate) Overdose?

Activated Charcoal (if OD occurred within last hour)




Fluid Replacement




IV Sodium Bicarbonate




Haemodialysis (if Severe Poisoning)

What is the Antidote for an Overdose of a Stimulant (ex. Amphetamines, Cocaine, Ecstasy)?

Agitation controlled with Diazepam or Lorazepam




Cool Patient to Treat Hyperthermia