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134 Cards in this Set

  • Front
  • Back
Cimetidine
H2 Receptor Antagonist
Ranitidine
H2 Receptor Antagonist
Omeprazole
Proton Pump Inhibitor

Pirenzepine

Muscarinic Stomach Antagonist



(The Original Anti-Ulcer Drug)


(Not used anymore due to side effects)

Aluminium Hydroxide
Antacid
Magnesium Hydroxide
Antacid
Sodium Bicarbonate
Antacid
Sucralfate
Mucosal Protectant
Colloidal Bismuth
Mucosal Protectant
Misoprostol

Synthetic Prostaglandin E1



Mucosal Protectant

Indomethacin

NSAID


Cyclooxygenase Inhibitor

Ibuprophen
Cyclooxygenase Inhibitor

Colchicine

Only ACUTE gout tx



Microtubule Assembly Inhibitor

Allopurinol

Competitive Xanthine Oxidase Inhibitor



Chronic gout tx

Probenecid
Uricosuric Agent
Sulphinpyrazone
Uricosuric Agent
Uricase
Uric Acid Metabolizer
Hydroxychloroquine
Disease Modifying Antirheumatic Drug (DMARD)
Sulphasalazine
Disease Modifying Antirheumatic Drug (DMARD)
Sodium Aurothiomalate
Gold Salt



Macrophage Suppression

Aurofin
Gold Salt



Macrophage Suppression

Penicillamine
Chelates Heavy Metals
Methotraxate
Folic Acid Antagonist

Leflunomide

Immunomodulatory



Dihydroorotate Dehydrogenase Inhibitor (mt)



stops denovo pyramide synthesis

Azathioprine

Imuran



Immunosuppressant



Autoimmune and organ rejection



Purine Analogue Cytotoxic to Inflammatory Cells

Cyclosporine
Antibiotic
Salbutamol
Beta 2 Agonist
Adrenaline
Non-Selective Adrenergic Agonist
Isoprenaline
Non-Selective Adrenergic Agonist

Theophylline

Asthma/COPD drug



Phosphodiesterase Inhibitor



Xanthine Class



All Alpha rec antagonist


Expands things

Ipratropium

Relieves bronchial spasms



Non-Selective Muscarinic Receptor Antagonist

Cromoglycate

Prophylactic Agent for Asthmatics



Keeps mast cells stable, from releasing histamines



Replaced by leukotrienes receptor antagonists

Beclomethasone
Glucocorticoid
Zileuton
5-Lipoxygenase Inhibitor
Zafirlukast
cysLT1 Receptor Antagonist

Montelukast

Blocks leukotriene D4 by binding it



Stops broncoconstriction and inflammation caused by leukotrienes



cysLT1 Receptor Antagonist

Nifedipine (Inhaled)

(procardia)



Calcium Channel entry Blocker



Arterial vasodilator



High ℅, contractility, hr

Verapamil (Inhaled)
Calcium Channel Blocker
Chromakalim
Potassium Channel Openers
Omalizumab
Anti-IgE Monoclonal Antibodies
Tropicamide
Muscarinic Antagonist
Timolol
Beta Receptor Antagonist
Dorzolamide
Carbonic Anhydrase Inhibitor
Pilocarpine
Muscarinic Agonist
Lanaprost
Prostaglandin F2 alpha Analogue
Verteprofin
Photodynamic Therapy Agent
Ranibizumab
VEGF Monoclonal Antibodies
Metronidazole
Prodrug of Cytotoxic, Antibiotic Compound



Clinically Used to Kill Amoeba and Anaerobic Organisms

Pentamidine
DHFR Inhibitor



Clinicallyused to treat Early Stage (non-CNS) in Trypanosomiasis (Sleeping Sickness)

Suramin

Multi-Enzyme Inhibitor



Clinically Used to treat Early Stage (non-CNS) in Trypanosomiasis




(Sleeping Sickness)


Melarsopol
Combination of Dimercaptopropanol and Melarsen Oxide (Arsenic Compound)



Clinicallyused to treat Late Stage (CNS) in Trypanosomiasis (Sleeping Sickness)

Sodium Stibogluconate
Anti-Protazoal Agent
Meglumine Antimonate
Anit-Protazoal Agent
Miltefosine
Anti-Protazoal Agent



Synthetic Ether Phospholipid Analogue

Ivermectin
Semisynthetic Macrocyclic Lactone



Clinically used against many Helminths and Arthropods

Piperazine
GABA Receptor Agonist



Clinically used (historically) to treat Round Worm and Pin Worm

Pyrantel Pamoate
Cation Channel Agonist



Depolarizing Neuromuscular Blocking Agent




Clinically Used as Third Line Agent against Hookworm, Pinworm, or Roundworm Infections

Albendazole
Microtubule Assembly Inhibitor



Anti-Helminthic Agent

Mebendazole
Microtuble Assembly Inhibitor



Anti-Helminthic Agent

Praziquantel
Anti-Helminthic Agent
Diethylcarbamizine (DEC)
Piperazine Derivative



Anti-Helminthic Agent

Erlotinib
EGFR Inhibitor



Anti-Cancer Agent

Cetuximab
Chimeric Mouse/Human IgG1 Monoclonal Antibody to EGFR (ErbB1)



Anti-Cancer Agent

Trastuzumab
Chimeric Mouse/Human IgG1 Monoclonal Antibody to EGFR (ErbB2)



Anti-Cancer Agent

Imatinib Mesylate
Tyrosine Kinase Inhibitor



Anti-Cancer Agent

Tipifarnib
Farnesyltransferase Inhibitor



Clinically used for Relapsed/Refractory AML

Sorafenib
Multiple rTK Inhibitor (VEGFR-1, VEGFR-2, PDGFR, and B-RAF Kinase)



Anti-Cancer Agent

Bortezomib
Proteasome Inhibitor



Anti-Cancer Agent

Bevacizumab
Humanised Mouse IgG1 Antibody against VEGF-A



Anti-Cancer Agent

Vatalanib
VEGFR-1 and VEGFR-2 Inhibitor
Rituximab
Anti-CD20 Antibody



Targets B Cell Non-Hodgkin's Lymphoma

Alemtuzumab
Anti-CD52 Antibody



Targets Chronic Lymphocytic Leukaemia

Gemtuzumab
Anti-CD33 Antibody Conjugated to Calicheamicin



Targets Acute Myeloid Leukaemia

Enfuvirtide
Anti-HIV Peptide



Fusion Inhibitor




Anti-HIV Drrug

Amantadine
Ion Channel Inhibitor



Anti-Influenza A Drug

Rimantadine
Ion Channel Inhibitor



Anti-Influenza A Drug

Raltegravir
HIV Integrase Inhibitor



Anti-HIV Drug

Zidovudine (AZT)
Thymidine Analogue



Nucleoside Reverse Transcriptase Inhibitor (NRTI)




Anti-HIV Drug

Lamivudine (3TC)
Cytidine Analogue



Nucleoside Reverse Transciptase Inhibitor (NRTI)




Anti-HIV Drug

Acyclovir
Guanine Base Attached to Incomplete Sugar



Anti-HSV/VCZ Drug

Efavirenz
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)



Anti-HIV Drug

Nevirapine
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)



Anti-HIV Drug

Ritonavir
HIV Protease Inhibitor



Anti-HIV Drug

Saquinavir
HIV Protease Inhibitor



Anti-HIV Drug

Zanamivir
Sialic Acid Analogue



Anti-Influenza Drug

Oseltamivir
Prodrug Sialic Acid Analogue



Anti-Influenza Drug

Ketoconazole

CYP450 Enzyme Inhibitor (specifically ones involved with production of Cortisol and Aldosterone)



Anti-Fungal Drug
Metyrapone
Reversible 11 beta - Hyroxylase Inhibitor

treating hypercortisonism


Diagnosis of adrenal insufficiency

Hydrocortisone (Cortisol)
Endogenous Glucocorticoid
Cortisone
Pro-Drug Version of Glucocorticoid
Prednisone
Pro-Drug Version of Glucocorticoid
Prednisolone
Synthetic Glucocorticoid

anti-inflammatory


used liver failure patients b/c unable to metabolise prednisone into prednisolone

Dexamethasone
Synthetic Glucocorticoid

25 times more potent than cortisol but minimal mineralocorticoid

Fluticasone
Synthetic Glucocorticoid
Beclomethasone
Synthetic Glucocorticoid
Methylprednisolone
Synthetic Cortisol Analogue
Fludrocortisone
Synthetic Cortisol Analogue with High Mineralocorticoid Activity
Spironolactone
Competative Aldosterone Receptor Antagonist



Potassium Sparing Diuretic

Eplerenone
Competitve Aldosterone Receptor Antagonist



Potassium Sparing Diuretic

Simvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Lovastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Pravastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Short Acting Statin

Atorvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Long Acting Statin

Rosuvastatin
HMG-CoA Reductase Inhibitor

(Reversible and Competitive)




Long Acting Statin

Gemfibrozil
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lowering Agent

Fenofibrate
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lowering Agent

Ciprofibrate
Peroxisome Proliferator Activated Receptor Alpha (PPAR-alpha) Agonist



Fibrate Lipid Lower Agent

Colestyramine
Bile Acid-Binding Resin



Lipid Lowering Agent

Colestipol
Bile Acid-Binding Resin



Lipid Lowering Agent

Ezetimibe
Niemann-Pick C1-like 1 (NCPC1L1) Cholesterol Transport Protein Inhibitor



Cholesterol Absorption Inhibitor

Niacin
Nicotinic Acid (Vitamin B3)



Lipid Lowering Agent

Omacor
Polyunsaturated Fatty Acids



(Ex. Eicosapentaenoic and Docosahexaenoic Acid)




Fish Oil Derivative




Lipid Lowering Agent

Aspirin
Irreversible Cyclooxygenase Inhibitor



First Line Anti-Platelet Agent

Clopidogrel
Irreversible ADP Receptor Inhibitor



Second Line Anti-Platelet Agent (or combo with Aspirin)

Prasugrel
Irreversible ADP Receptor Inhibitor



Anti-Platelet Agent

Dipyridamole
Phosphodiesterase Inhibitor



Anti-Platelet Agent (relatively weak)

Abciximab
Irreversible GPIIb-IIIa Antagonist (monoclonal antibody)



Anti-Platelet Agent

Eptifibatide
GPIIb-IIIa Antagonist
Tirofiban
GPIIb-IIIa Antagonist
Heparin (unfractionated)
Thrombin and Factor Xa Inhibitor



Anti-Coagulant

Dalteparin
Factor Xa Inhibitor



Anti-Coagulant




Heparin (low molecular weight)

Enoxaparin
Factor Xa Inhibitor



Anti-Coagulant




Heparin (low molecular weight)

Lepirudin
Direct Thrombin Inhibitor
Warfarin
Competitive Vitamin K Epoxide Reductase Component 1 (VKORC1) Inhibitor



Anti-Coagulant

Dabigatran
Direct Thrombin Inhibitor
Rivaroxaban
Factor Xa Inhibitor
Protamine Sulphate
Heparin Antidote
Streptokinase
Plasminogen Activator



Fibrinolysis/Thrombolytic Agent

Alteplase
Recombinant Tissue Plasminogen Activator (t-PA)



Fibrinolysis/Thrombolytic Agent

Tranexamic Acid
Lysine Analogue



Plasminogen Activation Inhibitor




Anti-Fibrinolytic Drugs

Aminocaproic Acid
Lysine Analogue



Plasminogen Activation Inhibitor




Anti-Fibrinolytic Drugs

Desmopressin

Synthetic ADH Analogue



Anti-Fibrinolytic Drugs



Helps clot

Etamyslate

Synthetic Haemostasis Drug



Stops bleeding



High capillary endothelial resistance and promote platelet adhesion via PGEs



for short-term blood loss in menorrhagia

Eptacog Alfa
Recombinant Factor VIIa