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18 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Thiazides act at the |
Distal tubule |
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Spironolactone acts at the |
Collecting tubules and ducts |
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Mannitol acts at the |
Proximal tubule and descending loop of H |
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Acetazolamide acts at |
Proximal convoluted tubule |
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Frusimide acts at the |
Thick ascending loop of H |
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Lithium is diluted at the |
Collecting tubule |
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Sulphinamides action |
Inhibit dihydrosteroate synthase (Folate) |
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Aminoglycosides eg gentamicin |
Irreversible inhibitor of protein synthesis |
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Macrolides eg erythromycin |
Ribosome translocation inhibition |
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Fluriquinolones eg ciproflixacin |
DNA gyrase inhibitor |
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4 cell wall synthesis inhibitors |
Penicillins Cephazolins Vancomycin Carbapenems |
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Example of a tetracycline |
Doxycycline! |
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50S subunit ribosome binding (4) |
Chloramphenicol Erythromycin Linezolid Clindamycin |
RAM MY LID AMY |
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Ciproflixacin inhibits |
DNA gyrase |
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Resistance to penicillins and b lactams is due to (4) |
Modify target PEnicillin binding proteins Impaired penetration of drug Efflux pump Betalactamase |
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Fluroquinolones may damage .... |
Growing cartilage in kids |
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Azole group reduce |
Ergosterol synthesis by inhib P450 enzymes |
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Clindamycin covers |
BOTH G- and G+ |
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