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18 Cards in this Set
- Front
- Back
pharmacodynamic
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sildenafil and nitroglycerin: sildenafil inhibits breakdown of cyclic gmp and nitroglycerin increases production
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pharmacokinetic
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alterations in absorption, distribution, metab or excretion
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cholestyramine and levothyroxine
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dec levo absorp
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antacid (ca al mg) and tetracyc
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dec tet absorption
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ferrous sulfate and tetracyc
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dec tetracyc absorption
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altered ph of gastrointes fluid
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cimetidine and ketocon--dec ketoconazole absorption by increasing gastric ph
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inducer of p 450's
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phenobarbital, carbamazepine, phenytoin, rifampin, st john wort
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inc renal excretion how
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alkanize urine of weak acid
or acidify for weak base |
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p450 inhib
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amiodarone, grapefruit juice, ketoconazole,
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ketoconazole and...
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terfenidine
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amiodarone and....
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warfarin
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ketoconazole and terfenidine can cause?
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torsade de pointe
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antimetabolite of terfinadine
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fexofenadine
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grapefruit juice and ....
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inc levels of felodopine (calcium channel blocker)
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inhibition of monoamine oxidase
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tyramine can release catecholamines but normally mao breaks down tyramine
but if inhib then can inc blood pressure also, mao inhib + serotonin reuptake inhib (prozac) can lead to serotonin syndrome |
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dec urinary excretion
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probenecid and penicillin, dec pen excretion
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another
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thiazide diuretic and lithium dec lith excretion
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inhib of p glycoprotein mediated transport
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quinidine and digoxin, inc plasma digoxin concentration
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