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19 Cards in this Set
- Front
- Back
Name 3 lipid-lowering agents?
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bile acid sequestrants
HMG-CoA reductase inhibitors miscellaneous |
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Name 3 bile acid sequestrants?
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cholestyramine
colesevelam colestipol |
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Name 6 HMG-CoA reductase inhibitors?
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atorvastatin
fluvastatin lovastatin pravastatin rosuvastatin simvastatin |
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Name 5 miscellaneous lipid-lowering agents?
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ezetimibe
fenofibrate gemfibrozil niacin niacinamide |
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Lipid-lowering agents are used as a part of a total plan including diet and exercise to reduce blood lipids in an effort to reduce morbidity and mortality of _________ cardiovascular disease and its _______.
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atherosclerotic
sequelae |
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Vytorin or
generic name ezetimibe/simvastatin is a new (July 2006) combination medication on the market that doctors are using in place of? |
Lipitor (newspaper)
manufactured for Merck/Schering-Plough Pharm. |
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Which group of lipid-lowering agents inhibit an enzyme involved in cholesterol synthesis?
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HMG-CoA reductase inhibitors
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Which group of lipid-lowering agents bind cholesterol in the GI tract?
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bile acid sequestrants
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The miscellaneous lipid-lowering agents act by other mechanisms and are separated in individual monographs.
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okay
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Contraindications?
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hypersensitivity
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Precautions?
Safety in pregnancy, lactation, and children not established. See individual drugs. Dietary therapy should be given a ___ to ____ month trial before drug therapy is initiated. |
2-3
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Interactions?
Bile acid sequestrants (cholestyramine and colestipol) may bind ____-____ vitamins (A,D,E, and K) and other concurrently administered drugs in the GI tract. The risk of myopathy from ______ reductase inhibitors is increased by niacin, erythromycin, gemfibrozil, and cyclosporine. |
lipid-soluble
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When assessing for use of lipid-lowering agents, obtain a diet history, especially in regard to ____ and ____ consumption.
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fat
alcohol |
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When assessing for use of lipid-lowering agents, lab tests that should be considered before initiating and periodically throughout therapy are?
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serum cholesterol levels
triglyceride levels (medication should be discontinued if paradoxical increase in cholesterol occurs) |
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When assessing for use of lipid-lowering agents, ____ function tests should be assessed before and periodically throughout therapy. May cause an increase in levels.
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liver
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Two potential nursing diagnoses are?
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Knowledge, deficient, related to disease processes and medication regimen
Noncompliance |
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IMPLEMENTATION:
See specific medications to determine ____ of doses in relation to ____. |
timing
meals |
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Advise patient that these medications should be used in conjunction with diet restrictions which include?
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fat
cholesterol carbohydrates alcohol (also teach patient about exercise and smoking cessation) |
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EVALUATION:
Effectiveness of therapy can be demonstrated by? |
decreased serum triglyceride and LDL cholesterol levels and improved HDL cholesterol ratios. Therapy is usually discontinued if the clinical response is not evident after 3 months of therapy.
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