Drug Class - Antiparkinsonism

Front 1

Name 3 anticholinergics?

Back 1

benztropine {Apo-Benztropine}, Cogentin

biperiden Akineton

trihexyphenidyl Artane

Front 2

Name 1 antiviral?

Back 2

amantadine
Symmetrel

Front 3

Name 2 catechol-O-methyltransferase inhibitors?

Back 3

entacapone Comtan
tolcapone Tasmar

Front 4

Name 6 dopamine agonists?

Back 4

bromocriptine
Parlodel

carbidopa/levodopa
Sinemet, Sinemet CR

levodopa
Dopar, Larodopa, L-dopa

pergolide
Permax

pramipexole
Mirapex

ropinirole Requip

Front 5

Name 1 monoamine oxidase type B inhibitors?

Back 5

selegiline Apo-Selegiline, Carbex, Eldepryl, Gen-Selegiline, Nu-Selegiline, {Novo-Selegiline}, SD-Deprenyl

Front 6

Name 5 groups of antiparkinson agents?

Back 6

anticholinergics
antiviral
catechol-O-methyltransferase
inhibitors
dopamine agonists
monoamine oxidase type B inhibitors

Front 7

.

Back 7

.

Front 8

Antiparkinson agents are used in the treatment of parkinsonism of various causes? (5)

Back 8

degenerative
toxic
infective
neoplastic
drug-induced

Front 9

What 2 neurotransmitters are antiparkinson agents trying to restore?

Back 9

acetylcholine
dopamine

Front 10

The imbalance is a deficiency in _____ that results in excessive cholinergic activity.

Back 10

dopamine

Front 11

______ inhibits the enzyme that breaks down levodopa, thereby enhancing its effects.

Back 11

Levodopa

Front 12

Anticholinergics should be avoided in patients with ____-____ glaucoma.

Back 12

narrow angle

Front 13

Use antiparkinson agents cautiously in patients with severe? (3)

Back 13

cardiac disease
pyloric obstruction
prostatic enlargement

Front 14

Which six antiparkinson agents may antagonize the effects of levodopa?

Back 14

pyridoxine
MAO inhibitors
benzodiazepines
phenytoin
phenothiazines
haloperidol

Front 15

Agents that antagonize dopamine (_____, _____) may decrease effectiveness of dopamine agonists.

Back 15

phenothiazines
metoclopramide

Front 16

Assess these parkinsonian and extrapyramidal symptoms (9) before and throughout course of therapy. On-off phenomenon may cause symptoms to appear or improve suddenly.

Back 16

akinesia
rigidity
tremors
pill rolling
mask facies
shuffling gait
muscle spasms
twisting motions
drooling

Front 17

Monitor blood pressure frequently during therapy. Instruct patient to remain ____ during and for several hours after first dose of _____, as severe hypotension may occur.

Back 17

supine
bromocriptine

Front 18

3 Potential Nursing Diagnoses?

Back 18

Mobility, impaired physical
Injury, risk for
Knowledge, deficient, related
to disease processes and
medication regimen

Front 19

In the carbidopa/levodopa combination, the number following the drug name represents the ______ of each respective drug.

Back 19

milligram

Front 20

Antiparkinson agents may cause _____ or _____. Advise patient to avoid driving or other activities that require alertness until response to medication is known.

Back 20

drowsiness
dizziness

Front 21

Caution patient to make position changes slowly to minimize?

Back 21

orthostatic hypotension

Front 22

Which three measures may patient use to decrease dry mouth?
Patient should notify hcp if dryness persists (saliva substitutes may be used). Also notify the dentist if dryness interferes with use of dentures.

Back 22

frequent mouth rinsing
good oral hygiene
sugarless gum or candy

Front 23

Advise patient to confer with hcp before ____ meds, especially cold remedies, or drinking alcoholic beverages.

Back 23

OTC

Front 24

Patients receiving levodopa should avoid ______?
Which vitamin may interfere with levodopa's action?

Back 24

multivitamins

vitamin B6 (pyridoxine)

Front 25

Advise patient to stay in air conditioning during hot weather as decreased _____ may occur.

Back 25

perspiration

Front 26

Advise patient to increase _____, _____, and ____ in diet to minimize constipating effects of medication.

Back 26

activity
bulk
fluid

Front 27

Advise patient to notify hcp if these 6 parkinsonian symptoms occur?

Back 27

confusion
rash
urinary retention
severe constipation
visual changes
worsening of parkinsonian
symptoms

Front 28

The effectiveness of therapy can be demonstrated by? (2)

Back 28

resolution of parkinsonian
signs and symptoms
resolution of drug-induced
extrapyramidal symptoms