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10 Cards in this Set
- Front
- Back
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What do antiarrhythmics do?
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suppression of cardiac arrhythmias
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Antiarrhythmics correct cardiac arrhythmias by a variety of ________
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mechanisms
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What is the therapeutic goal of antiarrhythmics? (2)
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decreased symptomatology
increased hemodynamic performance |
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What does the choice of agent depend on? (2)
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etiology of arrhythmia
individual patient characteristics |
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What should be corrected before therapy is initiated
(e.g., electrolyte disturbances, other drugs) |
treatable causes of arrhythmias
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How are antiarrhythmics generally classified?
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by their effects on cardiac conduction tissue
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What 3 drugs are also used as antiarrhythmics?
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adenosine
atropine digoxin |
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What is one major Class I drug that shares the properties of 1A, 1B, and 1C?
1A depresses Na conductance increases APD and ERP decrease membrane responsiveness 1B increase K conductance decrease APD and ERP 1C profound slowing of conduction markedly depress phase 0 |
moricizine
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What are 3 Class IA drugs that:
depress Na conductance increase APD and ERP decrease membrane responsiveness |
disopyramide
procainamide quinidine |
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What are 4 Class IB drugs that increase K conductance, decrease APD and ERP?
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lidocaine
mexiletine phenytoin tocainide |
