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14 Cards in this Set
- Front
- Back
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What are anti-Alzheimer agents used for?
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management of Alzheimer's dementia
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How do anti-Alzheimer agents work?
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act by increasing the amount of acetylcholine in the CNS by inhibiting cholinesterase;
no agents to date can slow the progression of Alzheimer's dementia. Current agetns may temporarily improve cognitive function and therefore improve quality of life |
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Which anit-Alzheimer agent should not be used in patients who have had previous hepatic reactions to the drug?
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Tacrine
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Why should antialzheimer meds be used cautiously in patients with a history of "sick sinus syndrome" or other supraventricular cardiac conduction abnormalities?
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may cause bradycardia
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Cholinergic effects may result in adverse GI effects and may also increase gastric acid secretion which results in?
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GI bleeding
(especially in concurrent use with NSAID therapy) |
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Adverse GI effects associated with antialzheimer drugs include the following symptoms?
Hint: There are 4 primary symptoms and 3 other cholinergic effects. |
4 primary:
diarrhea nausea vomiting weight loss 3 other: urinary tract obstruction seizures bronchospasm |
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Antialzheimer drugs may exaggerate the effects of what type of muscle relaxation during anesthesia meds?
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succinylcholine-type
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Do antialzheimer drugs increase or decrease the therapeutic effects of anticholinergic meds?
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decrease
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What aspects of cognitive function should be assessed throughout antialzheimer therapy?
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ability to perform simple
tasks attention language memory reasoning |
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What side effects should be monitored while on antialzheimers?
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anorexia
nausea vomiting weight loss |
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What are 3 potential nursing diagnoses?
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Thought processes; altered
Nutrition, altered: less than body requirements Knowledge deficit, related to medication regimen |
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What are two patient/family teaching tips?
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Take meds as directed
Notify hcp if anorexia, nausea, vomiting, or weight loss occurs |
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Clinical response due to the use of antialzheimer drugs will include?
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temporary improvement in
cognitive function in patient's with Alzheimers disease. The aspects of cognitive function that will be improved include: ability to perform simple tasks attention language memory |
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Four antialzheimer drugs are?
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donepezil Aricept
galantamine Reminyl rivastigmine Exelon tacrine Cognex |
