Dna Repair

Front 1

Agents that increase the number of mutations above background levels

Back 1

MUTAGEN

Front 2

Agents that cause damage to the DNA can lead to _________

Back 2

MUTATIONS

Front 3

________ normally screens out much of the harmful UV radiation in sunlight

Back 3

OZONE

Front 4

Repair system that targets a specific lesion in the DNA and repairs only that damage

Back 4

SPECIFIC REPAIR *

Front 5

Repair system that uses a single mechanism that repairs multiple kinds of lesions in DNA

Back 5

NON-SPECIFIC REPAIR*

Front 6

EXAMPLE USED IN CH 14 OF A SPECIFIC REPAIR FOR DNA MUTATED BY UV LIGHT

Back 6

PHOTOREPAIR

Front 7

UV radiation causes a mutation where thymine reacts and covalently links them together

Back 7

THYMINE DIMER

Front 8

NON SPECIFIC repair mechanism example in which a damaged region is removed and is then replace by DNA synthesis

Back 8

EXCISION REPAIR

Front 9

EXCISION REPAIRS THREE STEPS (R's):

in E. coli

Back 9

RECOGNITION (UvrABC completes)

REMOVAL (UvrABC completes)

RESYNTHESIS (UvrABC binds to damage and the cleaves a single stand on either side of the damage, removing it)

Front 10

IN THE SYNTHESIS STAGE OF EXCISION REPAIR DNA POL ___ OR POL ____ REPLACES THE DAMAGED DNA

Back 10

POLYMERASE 1

POLYMERASE 2