Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
Metformin- class of drug? |
Biguanides (sensitiser) |
|
|
Metformin- mechanism? |
Reduce hepatic glucose output Increase peripheral uptake of glucose |
|
|
Other name for glitazone |
Thiazolideones |
|
|
Class for pioglitazone |
Glitazone/thiazolidinediones (TZDs) |
|
|
Glitazone mechanism |
PPARy binding to increase cell sensitivity to insulin |
|
|
Example of a sulfonylurea |
Glipizide |
|
|
Mechanism of sulfonylureas |
Inhibit K channel of pancreatic beta cells causing insulin release |
|
|
Mechanism of meglitinides |
Short term boost of insulin- binds to K channel (same receptor but diff site to sulfus) on pancreatic b cells |
|
|
Example of alpha-glucosinidase inhib |
Acarbose |
|
|
Mechanism of a-glucosidase inhibs |
Slow digestion of starch in s.intestine |
|
|
Class for exanatide |
Incretin mimetic- GLP1 analogue/agonist |
|
|
Class for Vidagliptin |
DPP4 inhib |
|
|
Mechanism for vidaglip |
inhibits DPP4 (causes incretin breakdown) |
|
|
Class and mechanism for Dapagliflozin |
SGLT2 inhib= glucosuria |
|
|
Which anti DM drug can cause hypos |
Insulin and sulfonylureas |
