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10 Cards in this Set
- Front
- Back
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Diuretic Drugs |
Drugs that accelerate the rate of urine and the removal f Na+ and H2O |
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Carbonic Anhydrase Inhibitor (CAI's) Drugs |
Acetazolamide -treats edema Methazolamide -treats glaucoma |
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Carbonic Anhydrase Inhibitors: MOA |
Inhibits the carbonic anhydrase, decreases H+ ion concentration in renal tubules -increase excretion of HCO2, K+, Na+, H2O -reabsorption of H2O decrease, urine volume increase |
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Osmotic Diuretics Drugs |
Mannitol -crystallizes when exposed to low temps -pulls H2O in the proximal tubules -inhibits tubular reabsorption of H2O & solute producing a rapid diuresis |
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Thiazide Diuretics Drugs |
Hydrothiazide Chlorothiazide Trichlormethiazide |
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Like-Thiazide Drugs |
Chlorthalidone Metolazone |
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Thiazide and Thizaide-like Diuretics MOA |
-Inhibit tubular resorption of Na+, Cl-, K+ ions -action primarily in the DC -H20,Na+, Cl-, are excreted - K+ excreted to a lesser extent - dilate the arterioles by direct relaxation |
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Loop Diuretic Drugs (very potent) |
Bumetanide Furosemide Torsemide |
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Loop Diuretic MOA |
-Act directly on the ascending limb of the loop of henle to inhibit Cl- and Na+ reabsorption - Increase renal prostaglandians Resulting of dilated BV and decrease PVR |
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Potassium- Sparing Diuretics Drugs |
Amiloride Triamterene -block aldosterone effects by blocking Na+ channels Spironolactone - Aldosterone Antagonist blocks aldosterone effects by blocking aldosterone receptors |
