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9 Cards in this Set

  • Front
  • Back

Ectopic sources of Erythropoietin

Polycystic kidney


Cerebellar haemangioblastoma


Uterine fibroma


Renal carcinoma


Hepatoma


Phaeochromocytoma

Indications of Recombinant Human Erythropoietin

- Chronic renal failure


- Chronic inflammation


- Cancer with chemotherapy


- Zidovudine-induced anemia in HIV patients


- Anaemics with high risk for peri-operative blood loss from elective, non cardiac, non vascular surgery

Side effects of Recombinant Human Erythropoietin

- hypertension


- bleeding


- increased risk of thrombosis


- headache


- arthralgia


- nausea


- oedema


- diarrhoea


- progression of cancer

Haematopoietic growth factors

IL -1


IL -3


IL -6


EPO


G-CSF


GM-CSF


TPO

Causes of eosinophillia

Helminthic infestation


Loeffler's syndrome


Tropical eosinophillia


Allergic conditions


Drugs


Collagen vascular diseases


Malignancies


Idopathic hypereosinophilic syndrome

Cause of eosinophillia in allergic conditions

Hay fever


Asthma


Serum sickness

Drugs which cause eosinophillia

Sulphonamides


Aspirin


Nitrofurantoin


Penicillin


Cephalosporin


Allopurinol


Carbamazepine

Collagen vascular diseases causing eosinophillia

Rheumatoid arthritis


Churg-Strauss syndrome

Malignancies causing eosinophillia

Hodgkin's lymphoma


Chronic myeloid leukemia


Solid organ cancers


Eosinophilic leukaemia