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20 Cards in this Set
- Front
- Back
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1970s |
Isolation of a restriction enzyme that cuts DNA at specific sites Development of method to recombine the fragments, launching recombinant DNA technology ( genetic engineering ) |
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1972 |
First recombinant DNA molecules produced |
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1973 |
Introduction of recombinant plasmid vectors into bacteria for cloning |
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1975 |
DNA sequencing technology invented |
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1976 |
First clinical use of recombinant DNA for prenatal diagnosis of a-thalassemia |
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1977 |
Laboratory techniques for sequencing DNA invented |
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1978 |
Synthesis of the proinsulin peptide using recombinant DNA |
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1983 |
Discovery of PCR |
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1985 |
PCR used to amplify nucleotide sequences |
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1987 |
Production of a vaccine (anti-hepatitis B) based on recombinant DNA technology |
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1988 |
Incorporation and expression of genes inserted into mouse cells using retroviruses |
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1989 |
First human gene-sequenced, and a defect in the gene product shown to "cause" cystic fibrosis |
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1990 |
Gene for defective enzyme (adenine deaminase) required for nucleic acid synthesis replaced in affected humans |
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1994 |
Marketing in the US of FlavrSavr tomatoes, geneticists engineered for longer shelf life |
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1996 |
Birth of a lamb named Dolly, first animal to result from cloning an adult somatic cell |
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1999 |
Sequencing of a human chromosome and of complete fruit fly (Drosophila melanogaster) genome |
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2001 |
First draft sequences of human genome completed independently by the Human Genome Project and Celera Genomics |
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2002 |
Mouse genome sequenced; birth of first genetically modified cat |
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2003 |
Sequencing of 99% of the human genome completed to 99.9% accuracy, marketing of GloFish, a pet fish to which fluorescence gene was added |
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2006 |
Sequencing of the human genome completed |
