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15 Cards in this Set
- Front
- Back
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_______and _______are both Thiazolidinedione. They work by _______and ___________.There side effects include:1._______2.________3._______4.____________.
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Piolitazone and Rosiglitazone
decreasing insulin resistance and decreasing hepatic glucose output There side effects are weight gain, hepatotoxicity, peripheral edema and CHF |
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Which Thiazoglitazone is no longer recommended
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Rosiglitazone: Avandia
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What are alpha-glucosidase inhibitors and how do they work?
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There are two: arcabose (precose) and Miglitol (glyset).
They inhibit the hydrolysis of complex carbohydrates in the intestine. |
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What are the side effects aof acarbaose and miglitol
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Flattulence and diarrhea
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when are the alpha glucosidase inhibitors supposed to be taken?
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at mealtime.
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What are the usual doses of Arcabose ang miglitol
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SD 25 mg TID
MD 50 mg TID <60 kg 100 mg TID >60 kg |
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What is the mechanism of action of Pramlintide (symlin)
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It is a analog of amylin. It prolongs gastric emptying time and reduces postprandial glucagon secretion.
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How is pramlintide taken?
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in Type 1 anf type II diabetes as a SQ injection.
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_____ and ______ are both analogs of GLP-1. They increase inslin secretion and ______ gastric emptying. they ______ Beta cells growth and central appetite ___________
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Exantanide and Liraglutide are both analogs of GLP-1. They increase inslin secretion and slow gastric emptying. they increase Beta cells growth and central appetite suppression.
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GLP 1 analogs such as Exanatide and liraglutide are taken for which type of diabetes
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Type 2 DM
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What are the side effects of Exanatide and liraglutide?
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Weight loss, Nausea, pancreatitis.
Thyroid tumor (liraglutide) |
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Sitagliptine and Saxagliptine are _________inhibitors
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DPP-IV
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How do sitagliptine and saxagliptine work?
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They inhibit DPP-IV an enzyme responsible for the breakdown of GLP-1. this will increase insulin response and duration after a meal
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What are the side effects of sitagliptin and saxagliptin?
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Weight neutral, not likely to cause hypoglycemia
Infectious complications |
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Which diabetes product should be taken at mealtime:
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Alpha-glucosidase inhibitors: arcabose, miglitol
Meglitanides: Nateglinide, repaglinide |
