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83 Cards in this Set

  • Front
  • Back

Cells

Smallest living unit of organization

Tissues

Similar structured cells grouped together

Organs

Various tissues bonded together to form organs

Exocytosis

Transportation of materials from inside cell to outside of cell

Endocytosis

Intake of materials to the inside of the cell

Pinocytosis

Fluid or liquids ingested by cell

Phagocytosis

Engulfing and digesting of solid material by cell

Nucleus

Largest organelle in cell

Mitochondria

Organelles that manufacture energy

Ribosomes

Produces protein

Endoplasmic Reticulum

Membrane-bound organelle with rough or smooth channels, transports proteins

Golgi Complex

Segregates, packaging, and transporting of protein

Lysosomes

Intra and extracellular digestion (vacuoles)

Cytoskeleton and Inclusions

Metabolically inert transient substances, can be held for storage

Interphase

Cell is between divisions, growing and functioning

Prophase

First, chromatin condenses into chromosomes

Pro-Metaphase

Initiation of alignment of chromosomes

Metaphase

2nd, chromosomes align into equatorial position

Anaphase

3rd, separation of two chromatids

Telophase

4th, final phase with division into two daughter cells

Desmosomes

Intercellular junction between cells

Hemidesmosomes

Forms intercellular junction with noncellular surface.

Functions of Hemidesmosomes

Attach epithelium to connective tissue, gingiva to tooth, nail to nail bed, basement membrane to basal lamina

Four types of Tissue

1. Epithelial


2. Connective


3. Muscle


4. Nerve

Function of epithelial tissue

Covers and lines the internal and external body surfaces, involved in absorption, excretion, and sensory functions

Where does epithelial tissue originate from embryonically?

Can be any of the three embryonic cell layers, ectoderm, mesoderm, or endoderm

Histology of Epithelial Tissue

Avascular (relies on underlying connective tissue)

Basement Membrane

Always present between epithelium and connective tissue, produced by both of them, acellular

Layers of basement membrane

Basal Lamina - Superior portion, produced by epithelium, made up of Lamina Lucida and Lamina densa


Reticular Lamina - Inferior portion, produced by connective tissue


Retes Ridges

Interdigitation between outer epithelium and the deeper connective tissue

Connective Tissue

Derived from somites in the mesoderm, vascularized, involved in support, packaging, storage, transport, repair, and defense

Histology of Connective Tissue

Most common kind of cell is the fibroblast, can have three types of fibers (collagen, elastic, reticular)

Connective Tissue Proper

Called Lamina Propria in oral cavity, consists of loose connective tissue (padding layer) and dense connective tissue (reticular layer)

Specialized Connective Tissue

Adipose - contains little to no matrix


Elastic connective tissue

Cartilage

Noncalcified, avascular, forms temporary skeleton, present at articulating surfaces

Bone

Compact and loose osseous connective tissue, extracellular matrix becomes calcified

Blood

Connects body tissues together by supplying nutrients

Type I Collagen

Most common type in skin dermis, lamina propria, bone, and almost all connective tissue

Type II Collagen

In Hyaline and elastic cartilage

Type III Collagen

In granulation tissue produced quickly by young fibroblasts before tougher Type I is made, usually found alongside Type I

Type IV Collagen

Basal lamina, eye lens, filtration system of kidneys

Muscle Tissue

Striated, consists of myofibers, myofibrils, myofilaments, there are three classes (skeletal, smooth, cardiac)

Nerve Tissue

Nucleus with dendrites, cell body is surrounded by myelin sheath, and axon

Nervous System Division

CNS - brain and spinal cord


PNS - cranial and spinal nerves of somatic and autonomic nervous system

Autonomic NS Divisions

Sympathetic


Parasympathetic

Characteristics of Lining Mucosa

Nonkeratinized, has elastic fibers and can be stretched, fewer retes ridges, serves as a cushion, may have Fordyce's granules

Types of Lining Mucosa

Buccal mucosa


Labial mucosa


Alveolar Mucosa


Floor of mouth and ventral surface of tongue


Soft Palate

Characteristics of Masticatory MucosaK

Keratinized or Parakeratinized, rubbery texture, numerous retes ridges and C.T. papilla, thin or absent submucosa

Types of Masticatory Mucosa

Attached gingiva


Hard Palate


Dorsal surface of tongue

Specialized Mucosa

Lingual papilla on dorsal and lateral surfaces of the tongue, composed of epithelium and lamina propria (C.T.)

Types of Lingual Papilla

Fungiform


Foliate


Circumvallate


Filiform (only one without taste buds)

Cells in the Epithelium

Keratin, melanocytes, neutrophils, langerhans, merkel cells (touch receptor)

Nonkeratinized Epithelium in Oral Mucosa

Most common form of epithelium in oral cavity, contains at least 3 layers (Basal, intermediate, Superficial)

Basal Layer of Nonkeratinized Epithelium

Deepest layer, stratum basal, single layer of cuboidal cells attached to B.M., produces basal lamina portion of B.M., mitosis occurs in this layer ONLY

Intermediate Layer of Nonkeratinized

Stratum Intermedium, larger, stacked, polyhedral shaped cells, the bulk of the epithelium

Superficial Layer of Nonkeratinized

Stratum Superficiale, even larger stacked polyhedral cells, most superficial cells on the surface are flattened into Squames

Orthokeratinized Epithelium

Least common form in oral cavity (hard palate, attached gingiva, lingual papilla), forms keratin in superficial layers as it matures, contains 4 layers (basal, prickle, granular, keratin)

Prickle Cell Layer of Orthokeratinized Ep.

Stratum Spinosum, makes up the bulk of the epithelium, prickly because the desmosomal junction remains stretching the borders when cells lose their cytoplasm

Granular Layer of Orthokeratinized Ep.

Stratum Granulosum, contains flat cells in stacks of 3-5 cells thick, contain nucleus and keratohyaline granules

Keratin Layer of Orthokeratinized Ep.

Stratum Corneum, variable thickness depending on region, flattened cells with no nucleus, cytoplasm is filled with keratin, waterproof, soft, opaque, outer cells of the layer are squamous in shape

Parakeratinized Epithelium

More commonly found in masticatory mucosa, considered an immature form of orthokeratinized, normal in oral cavity but abnormal elsewhere, contains nuclei still in keratin layer

Hyperkeratinization

When nonkeratinized epithelium transforms and develops a keratin layer in response to trauma (linea alba)

Lamina Propria of Oral Mucosa

Has at least 2 layers - papillary, dense, and may have submucosa

Papillary Layer of Lamina Propria

Most superficial, consists of loose C.T., contains elastic fibers in lining mucosa, allows room for blood vessels and nerves

Dense Layer of Lamina Propria

Deeper layer, consists of dense C.T. with many fibers

Submucosa of Lamina Propria

May or not be present, more loosely compacted fibers, adipose tissue or salivary glands may be present

Characteristics of Attached Gingiva

Epithelium is thick and either kera or parakeratinized, contains retes ridges, and C.T. papilla, no submucosa, lamina propria acts as an added periosteum to the alveolar bone

Characteristics of Hard Palate

Thick layer of keratinized epithelium and a thick laminal propria, lateral portions have submucosa

Taste Buds

Contain 30-80 spindle shaped cells that extend from B.M. to the surface, turnover time is 10 days, taste pore is opening in epithelium that contacts the taste bud

Two types of cells in Taste buds

Supporting cells on outer portion


Taste cells located in the center that contain superficial taste receptors that produce the taste sensation

Filiform Lingual Papilla

Thread like, found on dorsum of tongue, highly keratinized with core of lamina propria, most numerous papilla

Fungiform Lingual Papilla

Mushroom shaped, contains numerous taste buds, thin layer of keratin over highly vascularized lamina propria, 1 mm in diameter

Foliate Lingual Papilla

4-11 vertical ridges on lateral borders of tongue, leaf shaped, contain taste buds

Circumvallate Lingual Papilla

7-15 large mushroom papilla, lined in V shape, 3-5 mm in diameter, taste buds located at base of papilla and empty into trench, contain Von Ebner's salivary glands in the submucosa

Pigmentation of Oral Mucosa

Normally pink-reddish pink, may be brown or black if melanocytes are present in the basal layer (these cells are derived from neural crest cells)

Turnover time for Junctional Epithelium

4-6 days

Turnover time for Buccal Mucosa

10-14 days

Turnover time for hard palate

24 days

General turnover time for other mucosa

4-24 days

How is tissue repaired?

Formation of a clot, epithelial cells migrate, immature C.T. is formed (granulation tissue) and is later replaced by scar tissue with numerous fibers

What happens to oral epithelium as a result of aging?

Reduction in stippling (fewer retes and papilla), enlargement of lingual veins, reduction in number and quality of taste buds, xerostomia, decreased keratinization, thicker collagen fibers, less resilient elastic fibers, slower repair

Sulcular Epithelium

Lines sulcus next to tooth

Junctional Epithelium

Attaches gingiva to tooth, usually at CEJ