Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
What does the VITAMINS acronym for causes of dementia stand for? |
Vascular Infectious Trauma Autoimmune Metabolic Iatrogenic Neoplasm Seizure |
|
What is the most common cause of dementia? |
Alzheimer's disease |
|
What are the next 2 common causes of dementia besides AD? |
- Lewy body dementia - Vascular dementia |
|
What is amyloid made of? |
A-beta-42 |
|
What neurotransmitter is deficient in AD patients? |
Acetylcholine |
|
What percentage of AD cases are familial? |
5% |
|
What are 3 genes involved in AD risk? |
- CLU - CR1 - PICALM |
|
What part of the brain is the main source of acetylcholine? |
Nucleus basalis of Meynert |
|
What kind of protein is beta-amyloid? |
Transmembrane protein |
|
What is Tau protein's function? |
To stabilize or repair microtubules |
|
What scale tests for Alzheimer's dementia?
|
Mini-mental Status Exam (MMSE) |
|
What is REM sleep disorder? How is REM sleep disorder treated? |
Acting out dreams as a result of Lewy Body Dementia
Clonazepam |
|
What protein is over-represented in Lewy Body Dementia? |
Alphasynuclein |
|
What is the treatment of DLB? |
Acetylcholine esterase inhibitors |
|
Name 2 acetylcholine esterase inhibitors |
- Donepezil - Rivastigmine |