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12 Cards in this Set
- Front
- Back
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What is a neoplasm? |
new, uncontrolled growth of cells that is not under physiologic control Benign or malignant |
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What are Carcinomas that form glandular configurations called? |
Adenocarcinomas. |
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What are cancers from soft tissue ? |
Sarcomas Generally large and composed of very pleomorphic spindle-shaped cells. |
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Example of metaplasia
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chronic irritation of cigarette smoke causing ciliated pseudostratifiedepithelium to be replaced by squamous epithelium more able to withstand theinsult |
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What is dysplasia? |
Icreasing degree of disordered growth or maturation of the tissue (often thought to precede neoplasia) such as cervical dysplasia as a result of human papillomavirus infection. Can be reversible before transformation to neoplasia has been made |
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normal cervical squamous epithelium stain features |
Thin and transparent cytoplasm - stains basophilic (stains with a basic dye - Haematoxylin) |
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What cells are collected in a Pap smear? What is the appearance of normal nuclei? |
Epithelia in uterine cervix Small nuclei and large amounts of cytoplasm. |
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What is a carcinoma called if the BM is still in tact? |
Carcinoma in situ
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What are sarcomas? |
Malignant neoplasms derived from connective tissue |
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What is the significance of mitotic figures in a neoplasm? I |
Higher rate of cellular proliferation. |
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What is anaplasia? |
Neoplasms with no differentiation |
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Sarcomas
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end to have a spindle cell pattern. Note that some of these neoplastic cells are much larger than others, and thus very pleomorphic. pleomorphic cells that vary markedly in size and shape. increased amounts of nuclear DNA, making them hyperchromatic. |
