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55 Cards in this Set

  • Front
  • Back
what are the three layers of the blood vessels
intima
media
externa
What do you find in the intima
endothelium
what do you find in the media
SM cells
elastic
fenestrated
describe the externa
outer layer of loose CT
support and provision of sm blood vessels and nerves
the _____ _____ is contains vasvasorum
tunica externa
aorta, pul trunk, pulm artery, brachicephalic, common carotid, subclaivian, an common iliac are all
elastic arteries
how can you distinguish elastic arteries
abundant elastic alminae in tunica media
what is the difference between muscular arteries and elastic artieries
ability to control lumen diameter and control blood flow rates
arteries have 5+ layers of ____ in the _____ _____
SM in the tunica media
how many layers of SM in the tunica media do arterioles have?
1 to 4
where do you find internal elastic lamina? external?
internal is between intima and media
external is between media and adventitia
what is the main detemrinant of bp
total peripheral resistance to blood flow
HTN depends on constriction of the tunica _______ of _______
HTN depends on the constriction of the media of arterioles
what regulates vasoconstriction
sympathetic vasoconstrictors
nerve fibers
NE
vasopressin
angiotensin II
what regulates vasodilation
vasodilator nerves
epi
ANF
what is the funciton of the tunica adventitia
support and provision of small blood vessels and nerves
depending on the size of the vessel, the tunica meia has varying amounts of elastic membranes and type _____ collagen
III
why do you need elastic arteries near the heart
so that during systole, the elastic sheets stretch to accommodate the large volume of blood leaving the ventricles
true or false. In resting tissue, only a small fraction of the available capillaries are open at any given time
TRUE!
what does peripheral resistancew dpend on
degree of contriction of the tunica media
what can lead to thickening of the tunica intima and gradual obstuction of the essel lumen
endothelial injury
when ednothelium is damaged what enters the tunica intima
monocytes and LDL cholesterol
In addition to monocyte and LDL cholesterol, _______ ______ _____ can migrate into the intima to contribute to the atherosclerotic plaque
smooth muscle cells
secretion of _____ and _____ ____ promotes the growth of the plaque by stimulating proliferation of SM cells and macrophages
cytokines and growth factors
In the kidneys, lungs, and livers, the capillary beds are very elaborately branched... why/?
high metabolic activties
where do you find continuous capillaries and why?
BBB
tight control via tight junctions and transcytosis
where do you find fenestrated capillaries and why?
intestinal vili, kidneys, choroid plexus, liver, endocrine glands

present where free exchange is desirable with tight junctions and fenestrae
where do you find discontinuous capillaries and why
sinusoids--> liver, spleen, bone marrow
where minimal control is necessary and slowed blood allows macrophages to remove debris and worn out RBCS
lymphatic capillaries are similar to what kind of blood capillaries
discontuous
what is the primary funciton of the lympathic system
to return lymphocytes and proteins to the blood
what are five ways to cross endothelia
diffusion
vesicular transport
fenestrae
paracellular pathway
endothelial discontinuities
how do lipid insoluble items get across endothelia
pinocytosis
transcytosis
during immune reaction, mast cell secrete histamine which causes the _____ junctions of _____ and _______ to become more permeable
tight junctions
venules
capillaries
if it is traveling with an arteriole, call it a
venule
True or false. When a lot of connective tissue is present, lots of exchange occurs
false! no exchange occurs
The thickest layer in the wall of a vein is the
tunica adventitia
after blood has flowed through the capillary bed is the pressure low or high?
low-- that's why you need valves
T or F. Only veins have valves
TRUE!
What are AVAs?
convey blood directly from arterial system to the venos system by bypassing the capillary bed
what happens when you open a shunt
you decrease flow to capillaries
you decrease heat loss
and conserve heat
________ is the development of a new blood vessel from an ______ _______
angiogenesis
existing vessel!
new vessels always originate as ____ from small venules or other capillaries
capillaries
______ ________ is when blood vessels anastomose with other vessels of the same dimension allowing for multiples routes for some part of the body
collateral circulation
why do you care about collateral circulation
clamping during surgery
def. cross connection between blood vessels
anastomosis
what stimulates the kidenys to excrete salt and water. also relaxes vascular smooth muscle to reduce blood pressure
ANF
what do you call a lymphatic capillary found in the center of the intestinal villi
lacteal
def. a t tubules and associated SR at the Z line in cardiac muscle
diad
def. a protein structures that can be opened and closed to regulate the passage of substances through the perforations of a fenestrated capillary
diaphragm
def. a structure comprised of actin filament insertion on the PM of a cardiac myocyte at intercalated disks
fascia adherens
def. a structure composed of spot desmosomes and fascia adherens that hold cardicac myocytes together
intercalated disk
what holds cardiac myocytes together
intercalated disk = spot desmosomes and fascia adherens
def. small blood vessels in the tunica adventitia that supply the tunica media of large blood vessels
vasa vasorum
what is a major difference between vein and venule
venules lack tunica adventitia
is a venule larger or smaller than a capillary
venules are larger than capillaries