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214 Cards in this Set
- Front
- Back
List 3 drugs that may exacerbate Asthma
|
***BAN
Beta Blockers Aspirin NSAID's |
|
How do you get a patient's Peak Expiratory Flow?
|
Patient has to stand up straight, hold peak flow meter horizontally, and blow into the meter. Repeat 2x and RECORD THE HIGHEST OF THREE READINGS.
|
|
What should be done if an Asthma Px is at Red Zone?
|
Take up to 3 treatments of 4-6 puffs of beta2-agonist every 20 min.
Take oral steroids (40-60mg, 3-10days) Go to ER or call 911 |
|
What should be done if an Asthma Px is at Yellow Zone?
|
2-4 puffs of Beta2-agonist Q20 min x 3 doses.
After 1 hr: If at green: beta agonist & inhaled steroid for 7-10 days If at yellow: beta agonist & oral steroid |
|
What are the other names for Beclomethasone?
|
QVAR
Vancenase/Beconase (nasal) Vancenase AQ/Beconase AQ (double strength nasal) |
|
What's the age range for QVAR?
|
5-11 yo: 40mcg, 1-2 puffs BID
Adults: 80mcg, 1-2 puffs BID |
|
What are the different brands names for Budesonide?
|
Pulmicort (Turbuhaler & Flexhaler) - DPI
Rhinocort (allergic rhinitis) Entocort EC (caps for Crohn's) |
|
What is the difference between Pulmicort Turbuhaler and Flexhaler?
|
Flexhaler has a dose counter
|
|
What is Entocort EC?
|
Budesonide capsules used for Crohn's.
|
|
List the lactose-containing inhalers (4)
|
Flexhaler (Pulmicort)
Asmanex Foradil Advair Diskus |
|
What are the other names for Flunisolide?
|
AeroBid
AeroBid-M (with menthol) Aerospan - comes with a spacer |
|
What is the strength and how is Medrol Dose Pack given?
|
Methylprednisolone = 4mg
Dose: taper over 6 days (21 tabs total) |
|
What are the medications used to prevent premature delivery?
|
Terbutaline
Alternatives: MgSO4, Indomethacin, Makena (NEW!!!!) |
|
What are the different brands for Mometasone?
|
Asmanex: for >12 yo
Nasonex: nasal Elocon: topical |
|
What are the brands for Fluticasone?
|
Flonase
Veramyst - has fluticasone furoate instead of fluticasone propionate Flovent (MDI & DPI) |
|
What is Alvesco? Dosing?
|
Ciclesonide, for >12 yo BID
|
|
What is Omnaris?
|
Ciclesonide for allergic rhinitis
|
|
What is Intal? Dosing?
|
Cromolyn, for >2 yo, 2 puffs QID
|
|
What is Tilade? Dosing?
|
Neodocromil, for >6 yo, 2 puffs QID
|
|
What the Long Acting Beta2-Agonists (LABA)?
|
Salmeterol (Servent)
Formoterol (Foradil) |
|
What is Servent? How long is it good for after opening?
|
Salmeterol; good for 6 weeks after opening foil
|
|
Dosing for Servent?
|
For >4 yo, 2 puffs BID or 30-60 min prior to exercise
|
|
Advair is good for how long after opening the foil?
|
1 month; for >4 yo
|
|
Foradil dosing?
|
BID or 1 puffs 10 min prior to exercise.
For >5 yo |
|
What is Symbicort? Good for how long? Age range?
|
Formoterol with Budesonide; good for 90 days after opening; for >12 yo
|
|
Brand names for Theophylline?
|
Elixophyllin
Theo-24 Uniphyl |
|
Aminophylline quivalence of oral to IV theophylline?
|
IV aminophylline = 85% of theo
PO aminophylline = 80% of theo |
|
What is the max dose for Theophylline?
|
900mg/day
|
|
What is the target serum concentration of Theophylline?
|
5 - 15 mcg/mL
|
|
SE of theophylline?
|
>15mcg/mL - toxicity
>30mcg/mL - SVT >50mcg/mL - seizure |
|
What are the Anti-Leukotrienes used for Asthma?
|
Montelukast (Singulair) - QHS
Zafirlukast (Accolate) - BID, empty stomach Zileuton (Zyflo) - BID |
|
What is the dosing for Singulair?
|
10 mg QHS > 15 yo
5 mg QHS : 6-14 yo 4 mg QHS : 2-5 yo |
|
Can you use Singulair to prevent exercise induced bronchospasm?
|
Yes; must be taken 2 hours prior to activity
|
|
What do you need to check with Zyflo?
|
LFT's
|
|
Zyflo can increase concentration of what medications?
|
Theophylline and Warfarin
|
|
What is Omalizumab? Dose?
|
Xolair (Omalizumab) is for >12 yo, 150-375mg SQ Q2-4 weeks
|
|
What is the blackbox warning for Xolair?
|
Anaphylaxis
|
|
Xopenex is good for how long after opening?
|
Open the foil, 2 weeks.
Open the vial, 1 week. |
|
What is Atrovent? Dose?
|
Ipratropium; 2-3 puffs QID
|
|
Atrovent is contraindicated in what allergy?
|
Soy and peanut allergy
|
|
What are the 2 brands for Ipratropium-Albuterol combination?
|
Combivent - inhaler
Douneb - nebulizer |
|
What is Tiotropium? Advantage over Atrovent?
|
Spiriva; once a day dosing compared to Atrovent which is QID
|
|
What is Brovana?
|
Aformoterol; an LABA nebulizer sol'n.
|
|
What is Performist? Storage?
|
Formoterol, an LABA nebulizer sol'n.; Fridge
|
|
What are the Dry Powder Inhalers?
|
Flexhaler (Pulmicort/Budesonide)
Advair Spiriva Foradil Flovent diskus Asmanex Serevent diskus |
|
Patient has hyperglycemia if fasting glucose is what? Post-prandial glucose of what?
|
FG >126 mg/dL
Post Prandial Glucose >200 |
|
A pregnant patient has hyperglycemia if FG is what?
|
FG >105
|
|
What are the two Diabetes meds for pregnant women?
|
Glyburide (Micronase, Diabeta)
Metformin (Glucophage) |
|
What are the 3 short acting insulins?
|
Lispro - Humalog
Aspart - Novolog Glulisine - Apidra |
|
What is Detemir? How long outside the fridge?
|
Levemir
Good for 42 days outside the fridge. |
|
What is Glargine? How long out of the fridge?
|
Lantus; good for 28 days out of the fridge.
|
|
What routes of injection can you give regular insulin?
|
IM, IV, SC
|
|
What routes of injection can you give Apidra?
|
IV and SQ
|
|
What is the insulin dosing for Type I & II Diabetes?
|
Type I: 0.5 - 0.8U/kg
Type II: 0.7 - 1.5U/kg |
|
What is Symlin? Dosing? #1 SE?
|
Pramlinitide (Symlin)
Type I: 15U TID AC Type II: 60U TID AC SE: Nausea |
|
Don't give Symlin to patients with?
|
A1C > 9%
Hypersensitivity to metacresol GI motility meds Alpha glucosidase inhibitors |
|
What are some of the symptoms for Diabetic Ketoacidosis?
|
***FAN
Fruity breat Abdominal pain N/V |
|
What is the DoC for renal patients with DM? Dose?
|
Glipizide, 30 min AC
Max: 20mg BID |
|
What are the other names for Glyburide? Max?
|
Diabeta & Micronase, max: 10mg BID
Glynase (micronized), max: 12mg |
|
What is Amaryl? Max?
|
Glimepiride
Max: 8mg |
|
What are the other names for Metformin? Max dose?
|
Glucophage, 2550mg
Glucophage ER & Glumetza, 2000mg Fortamet ER, 2500mg |
|
what is Glucovance?
|
Glyburide-Metformin
|
|
What is Avandamet?
|
Rosiglitazone-Metformin
|
|
What is Prandimet?
|
Repaglinide-Metformin
|
|
Caution/contraindication for the use of Metformin
|
Males: SCr>1.5
Females: SCr>1.4 Liver disease, COPD, CHF |
|
MoA of Thiazolidinediones? SE?
|
MoA: insulin sensitizers (Pioglitazone, Rosiglitazone)
SE: ***DALE Decrease bone density Avoid in CHF patients Liver disease Edema |
|
Patient has LFT's of >2.5x normal. Is it okay to give a thiazolidinedione?
|
DO NOT start medication if LFT's are >2.5x normal
|
|
What is Glyset?
|
Miglitol, alpha-glucosidase inh
|
|
What is Precose? Dose?
|
Acarbose, 100mg TID with food
If patient is <50kg, 50mg TID max. |
|
What is Repaglinide? Dose?
|
Prandin (Repaglinide)
Max: 16mg, 15 min AC |
|
What is Starlix? Dose?
|
Nateglinide (Starlix)
Max: 60-120mg, 30 minutes AC |
|
What is Sitagliptin? Dosing?
|
Januvia (Sitagliptin)
-CrCl>50mL/min: 100mg QD -CrCl 30-49mL/min: 50mg QD -CrCl <30mL/min: 25mg QD |
|
What is Saxagliptin? Dose?
|
Onglyza (Saxagliptin)
Max: 2.5mg for renal pts or if taken with inhibitors. |
|
SE for Gliptins?
|
Pancreatitis
Abdominal pain, N/V HA (headache) Upper respiratory tract infection |
|
What is Byetta? Dose?
|
Exenatide (Byetta)
Dose: 5-10mcg SC BID 60 min before meals (6 hours apart) |
|
Can you use Byetta if patient has CrCl <30? Storage?
|
No.
Storage: Fridge or 30 days RT |
|
Black box warning for Byetta?
|
Pancreatitis and Renal failure
|
|
What is Victoza? Dosing?
|
Lariglutide (Victoza)
Dose: 6mg SC daily >18 yo |
|
Black box warning for Victoza?
|
thyroid tumors
|
|
List meds that can cause Osteoporosis
|
Steroids
Anti-epileptic Aromatase inhibitors Gonadotropin RH |
|
What is Evista? Indications?
|
Raloxifene (Evista)
Breast Cancer & Osteoporosis |
|
What is Aredia? Dose?
|
Pamidronate
30-90mg IV infusion over 2-24H |
|
What is Alendronate?
|
Fosamax
|
|
What is Risedronate?
|
Actonel
Atelvia DR - can be taken WITH FOOD |
|
What is Ibandronate? Strengths?
|
Boniva, 2.5 & 150mg tabs
|
|
What are the other names for Zolindronic Acid?
|
Reclast, a yearly IV infusion
Zometa, 4mg IV infusion Q3-4W |
|
What is Zometa?
|
Zolindronic Acid, 4mg given in a 15 minute IV infusion
Indications: bone metastases/tumors, hypercalcemia, multiple myeloma |
|
What are the names for Calcitonin? Storage?
|
Miacalcin - inj & nasal spray, 35 days RT
Fortical - nasal spray, 30 days RT |
|
What is the dose for Miacalcin injection?
|
100U SC/IM daily
|
|
How many days can Fortical be out of the fridge?
|
30 days
|
|
Calcitonin is contraindicated in what allergy?
|
Salmon allergy
|
|
What is Forteo? Dose? Storage?
|
Teriparatide (Forteo)
Dose: 20mcg SC QD Storage: 28 days even if pen is not empty |
|
Other names for Estradiol (patch)? Frequency of dosing?
|
Menostar - 1 patch QW
Alora - 1 patch 2x QW Climara - 1 patch QW Combipatch - 1 patch 2x QW Vivelle Dot - apply twice a week |
|
What is Rheumatrex? Max dose?
|
Methotrexate
Max: 20mg QW |
|
What is the antidote for Methotrexate toxicity?
|
Leucovorin (folinic acid)
|
|
What do you monitor at baseline when giving Methotrexate?
|
CBC
Chest X-ray LFT Renal fxn |
|
Methotrexate adverse effects?
|
Mucocytosis
Pulmonary fibrosis Hepatotoxicity Renal toxicity Myelosuppression |
|
Absolute contraindications for the use of Methotrexate?
|
Pregnant & lactating women
SCr >1.5 Diarrhea or any infection Immuno-deficiency |
|
What is Arava? Dose?
|
Leflunomide
LD: 100mg PO QD x 3 MD: 10-20mg PO QD |
|
What is the half life of Arava? What can you use for a washout procedure?
|
2 weeks
Washout: Cholestyramine 8grams TID x 11 days |
|
What is Kineret? Dose? Storage?
|
Anakinra, interleukin-1 receptor blocker
100mg SC QD Fridge |
|
Kineret SE?
|
Neutropenia (monitor CBC)
|
|
What is Imuran?
|
Azathioprine
|
|
Imuran converts into what?
|
6-mercapto purine, which lowers the immune system
|
|
Cuprimine dosing?
|
Month 1: 250mg
Month 2: 500mg Month 3: 750mg Month 4: 1000mg Titrate slowly!!!!!! EMPTY STOMACH!!!! |
|
What is Hydroxychloroquine? Dose? SE?
|
Plaquenil (Hydroxychloroquine) is given 200mg BID.
SE: CNS effects and Retinopathy |
|
What is Azulfidine? Dose?
|
Sulfasalazine
500mg QD-BID after meals |
|
What allergy is Azulfidine contraindicated?
|
Sulfa
Salicylate |
|
What is Enbrel? Dose? Storage?
|
Etanercept (Enbrel) is a TNF blocker
Dose: 50mcg SQ weekly Storage: Fridge |
|
What is Remicade?
|
Infliximab (Remecade)
Dose: IV infusion 6x/year |
|
What is Humira? Dose?
|
Adalimumab (Humira)
Dose: 40mg Q2W on the front of the thighs or abdomen area |
|
What is Golimumab? Dose?
|
Simponi (Golimumab)
Dose: 50mg SC Qmonth |
|
What is the black box warning for Simponi?
|
Risk of TB invasive fungal infection
|
|
What is Cimzia?
|
Certolizumab
SQ 1-2x Qmonth |
|
What is Orencia? How is it given?
|
Abatacept
IV infusion Qmonth |
|
Orencia dosing?
|
<60kg 50mg
60 - 100kg 750 >100kg 1 gram |
|
What is Rituxan? Dose?
|
Rituximab
1 gram IV Q2 weeks (2 doses total) |
|
What do you premedicate with before using Rituxan?
|
Methylprednisolone, 100mg IV 30 minutes prior to infusion to prevent severe infusion reactions.
|
|
What is Aloxi? Half-life? Dose?
|
Palodosetron
Longest half-life (36 to 48H) Dose: 0.5mg 1H prior to chemo |
|
What is Dolasetron? Forms?
|
Anzemet comes in IV/PO
|
|
What is Zofran? Forms?
|
Ondansetron
IV/IM/PO/ODT |
|
What is Granisetron?
|
Kytril/
Sancuso (patch) - can be worn up to 7 days |
|
Are steroids good for N/V by themselves?
|
Yes, but also good when used with 5HT3 or Reglan
|
|
What is Decadron?
|
Dexamethasone
|
|
What is the prophylactic dose for Decadron?
|
8mg IV or 12mg PO prior to chemo
8mg PO QD for 2-4 days |
|
Treatment dose when using Decadron for N/V?
|
Dexamethasone (Decadron)
Dose: 10-20mg IV/PO Q4-6H |
|
What is Cesamet? What schedule does it belong?
|
Nabilone
Schedule II |
|
What is Marinol? What schedule does it belong?
|
Dronabinol
Schedule III |
|
What is the frequency of dosing for Marinol? Storage?
|
TID
Fridge |
|
What is the dosing frequency of Cesamet? Storage?
|
BID
Room temperature |
|
What is Emend? Dose?
|
Fosaprepitant
115 mg injection combined with 5HT3 blocker & steroid |
|
What is the dosing for Aprepitant?
|
1st day: 125mg PO
2nd & 3rd day: 80mg Use in combination with Decadron & Zofran |
|
What is the indication for Erythropoietin? Dose? Brands?
|
Anemia
SC 3x Qweek Procrit & Epogen |
|
What is Aranesp? Used for? Dosing?
|
Darbepoietin for chemo-induced anemia
2.25mg/kg SQ every week |
|
What is Neumega?
|
Oprelvekin, used for bleeding/thrombocytopenia
|
|
What do you need to monitor with Neumega?
|
Fluid & electrolytes
|
|
What is Filgrastim?
|
G-CSF, Neupogen
Used for Leukopenia (increase in infection) |
|
Points to remember for Neupogen & Neulesta?
|
Bone pain
Refrigerate (Neupogen: 24H RT; Neulesta: 48H RT) Protect from light. |
|
Filgrastim dosing? Storage?
|
Filgrastim (G-CSF, Neupogen)
5mcg/kg/day Fridge, use w/n 24H when room temp |
|
Neulesta dosing? Dosing?
|
6mg SC 1x each chemo cycle
Fridge |
|
What is the antidote for a high potassium level in the body?
|
Sodium polystyrene sulfonate (Kayexalate)
|
|
What is Herceptin?
|
Herceptin (Trastuzumab) is approved for the treatment of HER2 breast cancer in combination with Paclitaxel
|
|
What are the advantages of Aromatase Inhibitors over SERMs?
|
NO hypercalcemia
NO thromboembolism NO endometrial cancer |
|
Herceptin form? Dose?
|
Trastuzumab (Herceptin)
Form: IV infusion Dose: Initial - 4mg/kg over 90 minutes, then 2mg/kg over 30 minutes for 51 weeks. |
|
What is Tykerb? Dose?
|
Lapatinib (Tykerb)
Dose: 5 tabs daily x 21 days with XELODA (CAPECITABINE) |
|
What is Zolinza? Indicated for? Dose?
|
Vorinostat, for lymphoma
400mg QD with food |
|
What is Nolvadex?
|
Tamoxifen
|
|
Who is Tamoxifen indicated for?
|
Pre-menopausal women
|
|
What drugs should not be given with Tamoxifen?
|
Strong 2D6 inhibitors (Paxil, Prozac, Zoloft, Cymbalta, Amiodaron) bec. Nolvadex needs to be converted by CYP2D6 to its active metabolite
|
|
What is Evista?
|
Raloxifene
|
|
What is Anastrozole? Dose?
|
Arimidex (Anastrozole), 1mg QD
|
|
What is Letrozole? Dose?
|
Femara (Letrozole), 2.5mg QD
|
|
What is Exemestane? Dose?
|
Exemestane (Aromasin), 25mg QD
|
|
What is Ixabepilone? Dose?
|
Ixempra
40mg/m2 by IV infusion over 3 hours Q3 weeks |
|
Tykerb dosing?
|
Lapatinib, 5 tabs QD x 21 days with Capecitabine (Xeloda)
|
|
What is Megestrol?
|
Megace
|
|
What is Zoladex?
|
Goserelin
|
|
What is Lupron?
|
Leuprolide
|
|
What is Trelstar?
|
Triptorelin
|
|
What is Abarelix? Indication?
|
Plenaxis depot, for patients who can't have LHRH agonists
|
|
What is Eulixin?
|
Flutamide
|
|
What is Casodex?
|
Biclutamide
|
|
What is Nilandrone?
|
Nilutamide
|
|
What is Avodart?
|
Dutasteride
|
|
What is Finasteride?
|
Proscar, 5mg
Propecia, 1mg |
|
What do you give with Cisplatin? Why?
|
Amifostine (Ethyol), to protect the kidneys.
|
|
What do you give with Cyclophosphamide?
|
Mesna binds to acrolein, therefore works as prophylaxis against hemorrhagic cystitis
|
|
SE of Cyclophosphamide?
|
Hepatotoxicity
Nephrotoxic Hemorrhagic cystitis Agranulocytosis Alopecia Sterility problems |
|
What is Cytoxan?
|
Cyclophosphamide
|
|
What is Myleran?
|
Busulfan
|
|
What are the SE of Busulfan?
|
Increase in Uric Acid
Pulmonary fibrosis |
|
What is Treanda? Form?
|
Bendamustine, IV infusion
|
|
How do you reconstitute Treanda?
|
100mg in 20mL of Sterile H2O, transfer to a 500mL infusion bag of 0.9% NaCl
|
|
How long can you store Treanda?
|
24H if refrigerated or 3H at room temperature
|
|
Capecitabine is a pro-drug of what? Dosing?
|
5-Fluorouracil
2 weeks on, 1 week off (cyclical) Take 30 min PC in the AM & PM |
|
What is Cytostar?
|
Cytarabine
|
|
What is the antidote for cardiotoxicity due to Doxorubicin/Daunorubicin?
|
Dexrazoxane (Zinecard)
|
|
SE for Mitoxantrone?
|
Turns everything blue.
|
|
What do you premedicate with Docetaxel?
|
Decadron, 8mg BID x 3-5 days, start 1 day prior
|
|
What is Octreotide?
|
Sandostatin, unlabeled use for diarrhea
|
|
What are the brands for Formoterol?
|
Formoterol (Foradil) - DPI
Formoterol + Budesonide (Symbicort) >12 YO Formoterol + Mometasone (Dulera) >12 YO |
|
Asthma Management Stepwise Approach
|
Step 1: SABA (short acting Beta agonish) MDI PRN
Step 2: Low dose ICS Alt: Cromolyn or Leukotriene Inh Step 3: Low dose ICS + LABA Alt: Medium dose ICS Step 4: Medium ICS + LABA Alt: Medium dose ICS + LI, Theophylline or Zileutin Step 5: High dose ICS + LABA Step 6: High dose ICS + LABA AND ORAL STEROIDS |
|
What is Daliresp? Dose? SE/contraindication?
|
Daliresp (Roflumilast) is a phosphodiesterase 4 inh used for COPD.
Dose: 500mcg tabs PO SE: weight loss, liver impairment |
|
Daliresp drug interactions?
|
Daliresp (Roflumilast) is a CYP3A4 substrate
|
|
Symlin storage?
|
Unopened vials: Fridge
Opened: Fridge or RT for 28 days |
|
DKA Treatment
|
1. Hydrate with 0.9% NaCl
2. Give Insulin to transfer sugar from the blood to the cells 3. Give more glucose when levels drop below 250 |
|
What are the Oral DM agents?
|
Sulfonylureas: Glimepiride, Glipizide, Glyburide
Biguanides: Metformin Thiazolidinediones: Rosiglitazone, Pioglitazone Alpha-glucosidase inhibitors: Acarbose, Miglitol Meglitinides: Repaglinide, Nateglinide Bromocriptine |
|
What is the difference between Dawn Phenomenon and Somogyi Effect?
|
Somogyi Effect: body gets hypoglycemic (<60) therefore it tries to compensate which results to high glucose levels in the morning
Dawn Phenomenon: happens to everyone when the body releases cortisol, epi and other hormones to help regulate the body which in turn increases glucose levels; if the body doesn't have enough insulin, this results to high glucose levels in the morning |
|
Alpha glucosidase MoA? SE?
|
Alpha glucosidase: Acarbose & Miglitol
MoA: prevents breakdown of polysacchardies (sucrose) and DELAYS absorption SE: GI effects & elevated LFT's |
|
Meglitinides MoA? SE?
|
Meglitinides (Prandin, Starlix) stimulates insulin secretion.
MoA: weight gain & hypoglycemia |
|
What is Tradjenta? Dose? SE?
|
Tradjenta (Linagliptin) is given 5mg PO QD.
SE: same as other gliptins Don't give to patients with renal or hepatic impairment. |
|
What is Cycloset? Dose? Max?
|
Cycloset (Bromocriptine) is a dopamine receptor agonist used for DM.
Dose: 0.8mg tabs given within 2 hrs of waking up in the morning WITH FOOD Max: 6 tabs |
|
What is Xgeva?
|
Xgeva (Denosumab) is to prevent skeleta-related events in cancer patients with bone metastases from solid tumors
Form: SC 120mg/1.7mL Dose (postmenopausal osteoporosis): 60mg Q6 months |
|
Brands for Denosumab?
|
Xgeva
Prolia |
|
What is Prolia? Dose? Storage?
|
Prolia (Denosumab)
Dose: 60mg Q6 months Storage: Fridge, let stand @ RT for 15 minutes prior to use |
|
What is Actemra? Dose?
|
Actemra (Tocilizumab) is an interleukin-6 receptor inhibitor used for RA
Dose: 4-8mg/kg IV infusion (60 minutes) |
|
Monitoring parameters for Actemra?
|
Actemra ( Tocilizumab)
Don't start if: ANC <2000 Platelets <100,000/mm3 ALT/AST >1.5 x ULN |
|
List the Aromatase Inhibitors
|
***ALE
Anastrozole (Arimidex) Letrozole (Femara) Exemestane (Aromasin) |
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List the Tyrosine Kinase Inhibitors
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***NILE - all PO
Nilotinib (Tasigna) Imatinib (Gleevec) Lapatanib (Tykerb) Erlotinib (Tarceva) |
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List the anti androgens
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***No Boy Friend, No Crazy Experience
Nilutamide (Nilandrone) Biclutamide (Casodex) Flutamide (Eulixin) |
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What are the 5-HT3 inhibitors used to treat N/V?
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***PDOG
Palodosetron (Aloxi) - IV/PO Dolasetron (Anzemet) - IV/PO Ondansetron (Zofran) - IV/PO/IM/ODT Granisetron (Kytril, Sancuso) - IV/PO/patch |
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What is Sancuso? Dose?
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Granisetron (Kytril, Sancuso)
Dose: 1 patch Q7days, avoid the sun |
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Name the cannabinoids used for N/V
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Marinol (Dronabinol)
Cesamet (Nabilone) |
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Name the NK1 receptor antagonists used for N/V
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Aprepitant - PO
Fosaprepitant (Emend) - IV |
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Points to remember for Aranesp
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Aranesp (Darbepoietin)
1. Don't shake 2. Protect from light 3. Fridge 4. Clear and colorless |
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Medications used for chemo-induced neutropenia
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Filgrastim (G-CSF, Neupogen) given 5mcg/kg/day
Pegfligrastim (Neulesta) given 6mg SC 1x every chemo cycle. |
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List the Alkylating Agents for Chemo
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Cisplatin, Carboplatin, Oxaloplatin
Busulfan Cyclosphosphamide, Ifosphamide, Temozolomide Carmustine, Lomustine Streptozosin Melphalan, Mechlorethamine, Altretamine Dacarbazine, Procarbazine Bendamustine (Treanda) |
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List the Anti-metabolites for Chemo
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Methotrexate
Fluorouracil (5-FU) Mercaptopurine (6-MP) Cytarabine, Fludarabine, Capecitabine, Cladribine Pentostatin Thioguanine Hydroxyurea |
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List the Antibiotics for Chemo
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Bleomycin
Dactinomycin Daunorubicin, Valrubicin, Doxorubicin Epirubicin, Idarubicin Mitomycin, Plicamycin Mitoxantrone |
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What are the other names for a vertical flow hood?
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Type 2 Cabinet
Class 2 Cabinet |
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What is given with Platinol to prevent nephrotoxicity?
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Amifostine is given with Platinol (Cisplatin) to prevent nephrotoxicity.
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What is Faslodex? Form? Dose?
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Faslodex (fulvestrant) is an estrogen receptor antagonist (HER2)
Form: IM Dose: slow IM inj in each buttock on days 1, 15, 29 and then Qmonth thereafter. |
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SE for Faslodex?
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Faslodex (fulvestrant)
Bleeding hepatic impairment Pregnancy Cat. D |
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What is Halaven?
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Halaven (eribulin) is a microtubule inhibitor for late stage disease chemo
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