Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
53 Cards in this Set
- Front
- Back
|
Define the physiological process of cough. The three phases. |
|
|
|
Clinically define cough. |
|
|
Draw this. |
|
|
Draw this. |
q |
|
|
Define acute cough, subacute cough, and chronic cough. |
|
|
|
What are the two major types of cough? |
Productive and non-productive |
|
|
Define productive cough. What does each color of secretion imply? Clear, purulent, yellow, and malodorous |
|
|
|
Define non-productive cough. What are some possible causes of a non-productive cough? |
|
|
|
What are some complications of cough? |
|
|
|
What are some non-pharmacologic treatments for cough? |
|
|
|
ANTITUSSIVES: What are the drugs of choice of non productive coughs? Systemic agents (3) and topical agents (2)? |
|
|
|
EXPECTORANTS What is the drug of choice for productive cough with thick secretions? |
|
|
|
Dextromethorphan: Active ingredient in which cold medicine? What is the mechanism of action? Metabolized how? Opiod or nonopiod? Onset and duration? Is it safe? |
|
|
|
What are some side effects of dextromethorphan? |
General AEs |
|
|
Who's should not take dextromethorphan? |
Obvious stuff, be careful taking ANY drugs that raise serotonin levels |
|
|
Diphenhydramine: Drug type? Mechanism? Antitussive effects? Onset and duration? When used? |
|
|
|
Side effects and contraindications of diphenhydramine? |
|
|
|
Codeine (3-methylmorphine):
Drug type? Mechanism? Onset, duration? Metabolism? |
|
|
|
Side effects of codeine (3-methylmorphine): |
|
|
|
Contraindications of codeine (3-methylmorphine): |
|
|
|
How are the topical agents applied? Look over slide. |
|
|
|
Guaifenesin (Mucinex): What is it used for? Drug type? Used for chronic cough? How does it work? FDA approved? |
|
|
|
Side effects of guafenesin (mucinex)? Contraindications? |
Hypersensitivity |
|
|
|
|
What the hell? |
|
|
|
What are nasal decongestants? Do they affect release of histamine or any mediators involved in the allergic reaction? What are they commonly formulated with? |
|
|
|
What is the mechanism of action of nasal decongestants? What type of agonist? What do they stimulate? What three things does this decrease? |
|
|
|
Difference dosage forms of nasal decongestants?
Two different types of oral decongestants? |
|
|
|
How does pseudo ephedrine act primarily? What does it stimulate? What is it rapidly metabolized by? Where? |
|
|
|
What is PE metabolized to a minor extent by? Does it have a better bioavailability than phenylephrine? |
|
|
|
What are some of the major side effects of systemic decongestants (think about what they are acting on = alpha adrenergics)? |
|
|
|
What are some precautions and contraindications for PE? |
|
|
Look over. |
|
|
|
What are the three types of topical nasal decongestants? What is an example of a spray? When is it preferred? |
|
|
|
What is another spray type (don't give it to meth heads!)? |
|
|
|
Some advantages of sprays? Disadvantages? |
|
|
|
Some advantages of drops? Disadvantages? |
|
|
|
Two drugs types for inhalers? |
|
|
|
|
|
|
What do mucolytics promote? When are they used? Which diseases? |
|
|
|
What is mucus? What makes up backbone? What makes side chains? What holds it together? Intramolecular bond type and intermolecular bond type? |
|
|
Look over. |
|
|
|
How do you facilitate mucus clearance (goals)? water, causes, clearance, inflammation |
|
|
|
What do bland aerosols do? What are they also known as? What are some difference types (4)? |
|
|
|
What are the three types of expectorants? Function of each? |
|
|
|
Commonly used mucolystics: 1. N-acetyl cysteine. Mechanism? How given? Other effects? |
|
|
|
Side effects and precautions with N-acetyl cysteine? |
|
|
|
Additional side effects and precautions of n-acetyl cysteine? (mucus production, antibiotics, general, any smells, storage) |
|
|
|
Mucolytic: 2. Sodium bicarbonate Mechanism? How administered? What does pH increase do? Is it irritating? |
|
|
|
Mucolytic: 3. Dornase alfa (pulmozyme) Mechanism? Composition? Effects?
Indications? (diseases) Does it have an effect on non-infected sputum? |
|
|
|
Side effects of dornase alpha (pulmozyme)? Contraindications? |
Contra: In patients hypersensitive to Chinese Hamster Ovary cell products |
|
|
Mucolytics: 4. Amiloride
Mechanism? Drug type? When given? Why given for CF? Prevents what? Other uses? Administration? |
|
|
|
Mucolytics: 5. Denufosol Tetrasodium
Mechanism? What type of drug is it? |
|
