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........... is the most prevalent form of arthritis in West Africa.
Osteoarthritis is the most prevalent form of arthritis in West Africa.
Symptoms occur earlier and appear to be more severe in ?
Symptoms occur earlier and appear to be more severe in women.
Epidemiology of Osteoarthritis
Drop 2 points
1. Osteoarthritis is the most prevalent form of arthritis in West Africa.
2. Symptoms occur earlier and appear to be more severe in women.
Osteoarthritis is A degenerative, non-inflammatory joint disease characterized by
1. destruction of articular cartilage and
2. formation of new bone at joint surfaces and margins.
Define Osteoarthritis
A degenerative, non-inflammatory joint disease characterized by destruction of articular cartilage and formation of new bone at joint surfaces and margins”
Osteoarthritis is purely a degenerative disorder.
True or false
False.
It is not a pure degenerative disorder but a dynamic phenomenon since it shows features of both destruction and repair
With Age, cartilage shows,
1. Diminished cellularity,
2. Reduced proteoglycans concentration,
3. loss of elasticity and
4. a decrease in breaking strength .
List the aetiology of osteoarthritis
1. Age; with age cartilage shows
a. diminished cellularity,
b. reduced proteoglycans concentration,
c. loss of elasticity and
d. a decrease in breaking strength .
2. Cartilage problems:
a. crystal deposition diseases,
3. Genetic defects in type 11 collagen
4. Previous inflammatory disorders
5. Destruction and reduced synthesis of proteoglycan: e.g.
a. synovial and leucocytes enzymes causing leaching, while
6. Deformities, joint incongruity and instability: increases mechanical stress due to abnormal loading in knee deformities and acetabular
7. Changes in subchondral bone: malunited fractures
8. Joint dysplasias
9. Occupation: Those which cause repetitive stress eg
a. knee bending activities
b. Footballers and athletes
10. Bone density- (genetic, hormonal & metabolic factors)
11. Obesity
12. Family history
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