term1 Definition1term2 Definition2term3 Definition3
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Resolution
-complete rstoration of normal structure and function of tissue
- mild injury with minimal tissue damage will
resolve eg. mild thermal burn
Abscess formation
- a pus filled cavity is an abscess - pimple
-suppurative exudate or pus = necrotic tissue neutrophils and pyogenic bacteria
-eg. acute lung abscesses due to staphylococcal infection
Repair ( healing)
-necrotic tissue is removed and replaced by :
regeneration = division of surviving
parenchymal cells eg. liver, bone, kidney may regenerate but not brain (organ doesn't
regeneration)
organizaton = fibroblasts recruit to necrotic, deposits collagen
-usual outcome, rapid replacement of
specialized cells by a collagen scar
Granulation tissue
-forms the scar and consists of fibroblasts producing collagen, new capillaries providing nutrients, and macrophages
-mature scar = collagen tissue
-healing is an energy dependent process (ATP) = need good oxygen supply
Chronic inflammation
-inflammation becomes long-standing
-injury persists leading to constant inflammation as well as constant attempts at healing
-immune system cells are recruited
-lymphocytes found in tissue and usually much scar eg. chronic peptic ulcer
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