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A Nature Cleaning Mechanism of Epithelial Cells ...
High Turnover Rate
Biofilm =
Microbial + Matrix of Extracellular Polymeric Substances
The Species in Early colonization
-Actinomyces species
-Yellow Complex: Streptococcus
-Green Complex: Capnocy/ A.A./
E. corrodens/ Campylobacter consisus
-Purple Complex: V. parvula/ A. odontolytius
The Species in Late colonization
(Major etiology of perio. disease =>Gram - )
-Orange complex: Campylobacter gracillis,
C. rectus, P. intermedia, F periodonticum
-Red complex: T. forsythia, P. gingivalis,
Tr. denticola
Majority nutrients for biofilm come from ...
-Saliva
-Cervicular fluid
Non-Specific Plaque Hypothesis
-Quantity of plaque
-Gingivitis +Time = Periodontitis
Specific Plaque Hypothesis
-Not about the quantity but the TYPE of bacteria
-Gram - (Anaerobic bacteria)
Criteria of
Periodontal Pathogens
-Association between bacteria species and periodontal disease
-The elimination should release the disease
-The host response must be detectable
-The bacteria must have virulent factors which play a role in the disease process
-Reproducibility in animal model study
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