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What things will increase INR when on warfarin? (More bleeding)
Liver disease, cranberry juice, NSAIDs
P450 inhibitors: ciprofloxacin, erythromycin, isoniazid, cimetidine, omeprazole, amiodarone, allopurinol, fluconazole, SSRIs, alcohol, tamoxifen
Which things decrease INR? (More clotting)
Anti-epileptics (phenytoin, carbamazepine), rifampicin, St. John’s wort, chronic alcohol
PC BRAS
Phenytoin, Carbamazepine, Barbiturates, Rifampicin, Alcohol, Sulphonylureas
What does St. John’s wort affect?
Decreases levels of warfarin, ciclosporin, COCP
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