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What do all of these organisms cause?
Inflammatory diarrhea
Non-inflammatory diarrhea
What type of organisms are these?
Anaerobes
What is the definition of acute diarrhea?
Chronic diarrhea?
Acute = 3 or more loose stools per day lasting less than 2 weeks
Chronic = persists for greater than four weeks
What is inflammatory diarrhea? What cells will you see in the stool? Is fever common? Is the volume large or small? What part of the GI tract is commonly affected?
Contrast all of this with non-inflammatory diarrhea.
How many microbes in the gut?
Which group is a major contributor to the gut microbiome? Which two types specifically?
Where are these organisms also present?
What two enzymes do anaerobes lack (this is why the growth of anaerobes is inhibited by oxygen)? What are these enzymes used to eliminate?
Do anaerobic infections stink? Does lack of a smell rule out anaerobes?
Anaerobic flora cause disease (abscesses) when they are introduced into normally _____ sites or when the balance of organisms is upset and pathogenic organisms _____. Species found in _____ often reflect the normal flora in that site.Anaerobic infections are often _____ (mixed anaerobic and facultative aerobic bacteria)Environmental anaerobes also cause disease (tetanus, _____, gas gangrene)
Anaerobic flora cause disease (abscesses) when they are introduced into normally sterile sites or when the balance of organisms is upset and pathogenic organisms overgrowSpecies found in abscesses often reflect the normal flora in that site.Anaerobic infections are often polymicrobial (mixed anaerobic and facultative aerobic bacteria)Environmental anaerobes also cause disease (tetanus, botulism, gas gangrene).
Bacteriodies fragilis:
Gram negative or positive?
Predominant organism in what part of the GI tract?
Most common cause of what?
What do infections usually arise from?
What is an important virulence factor?
What plays an important role in abscess formation?
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