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Hydralazine with isosorbide denigrate (BiDil)
Direct vasodilator
PO: 1-2 tablets tid (each tablet contain 20 mg isosorbide dinitrate and 37.5 mg Hydralazine) (max: 2 tablets/day)
Headaches, flushing of face, orthostatic hypotension, dizziness, reflex tachycardia
*fainting, severe headaches, severe hypotension with overdose, lupus like reaction (Hydralazine)
Nesiritide (Natrecor)
IV: 2 mcg/kg bolus followed by continuous infusion at 0.01 mcg/kg/min
Hypotension, increased serum creatinine, headache
*dysrhythmias
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