term1 Definition1term2 Definition2term3 Definition3
Please sign in to your Google account to access your documents:
What five types of different forms of metabolism are there?
-oxidation
-reduction
-Acetylation
-Hydrolysis
-Conjugation
What two phases of drug metabolism are there?
-Phase I is Oxidation/reduction/Hydrolysis
-Phase II is conjugation
What isoforms of CYP450 enzymes are there?
-CYP1A2
-CYP3A
-CYP2C9
-CYP2C19
-CYP2D6
How does the cytochrome P450 system nomenclature work e.g. for CYP2D6?
-CYP = cyctochrome P450
-2 = genetic family
-D= genetic sub-family
-6 = specific gene
-nomenclature is genetically based , it has no functional implication
What is the effect of any drug with regards to its metabolism?
-The route in which it is metabolised
-Whether the drug or its metabolite is "active"
-Whether its pathway is affected by the polymorphism
-Whether there is the route compensated by other enzymes
Need help typing ? See our FAQ (opens in new window)
Please sign in to create this set. We'll bring you back here when you are done.
Discard Changes Sign in
Please sign in to add to folders.
Sign in
Don't have an account? Sign Up »
You have created 2 folders. Please upgrade to Cram Premium to create hundreds of folders!