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What is the name for how signals are transmitted from the outside of the cell to the inside, allowing cells to modify their behavior?
Signal Transduction
How are signals transmitted across the membrane?
1.) Hydrophobic signaling molecules can cross the membrane DIRECTLY (steroid hormones and dissolved gas like NO and CO)
2.) Hydrophilic signaling molecules CANNOT cross the membrane so we need to INDIRECTLY signal across the membrane by binding the the extracellular domain of transmembrane receptor proteins
Types of Signals
1.) Signaling via Chemical Messengers:
-Autocrine, paracrine, and endocrine signaling
-Cell surface receptor binds a molecule secreted by itself (autocrine), a nearby cell (paracrine), or a distant cell (endocrine)
2.) Contact dependent signaling:
-Cell surface receptor binds a signal on the surface of another cell or to the extracellular matrix
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