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Renin
An enzyme that acts as a catalyst for the conversion of angiotensinogen to angiotensin I
Released by the kidneys
Angiotensinogen
A plasma protein released by the liver
Angiotensin I
The protein angiotensinogen is split by the enzyme renin and converted into this.
Angiotensin II
The result of angiotensin I conversion
Stimulates the rise in blood pressure through action in the systemic arterioles, adrenal gland, and posterior pituitary gland
What action does angiotensin II take in the posterior pituitary gland?
Angiotensin II stimulates the release of antidiuretic hormone
This leads to an increase in water reabsorption in the kidneys, which increases blood volume
What action does angiotensin II take in the adrenal glands?
It stimulates the release of aldosterone, which increases sodium and potassium reabsorption. This in turn increases water reabsorption, which increases blood volume.
It also stimulates the release of cortisol, which increases blood pressure
What action does angiotensin II take in the systemic arterioles?
It causes peripheral vasoconstriction which increases blood pressure
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