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Mechanism of action of cyanide poisoning?
Bind to cytochrome oxidase and inactivates and thus cell cannot produce ATP
Drug of choice for cyanide poisoning
Hydroxocobalamine(vit b12) on administration changes to cyanocobalamine(vit b12)
Another drug also can be given is?
Amyl nitrite ,sodium thio suphate -- --amylnitrate converts hemoglobin to methhemoglobim and then methhemoglobim combines with cyanide to form cyanomethhemoglobin (it is also harmful )and then convertin to sodium thio cyanide and excreted
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